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Search Results for " clu "

Targets Recommended: HBV

14

抑制剂 & 化合物

2

天然产物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T35373L	Bulevirtide (Myrcludex B) acetate	HBV	Microbiology/Virology
	Bulevirtide (Myrcludex B) acetate 是一种病毒粒子进入抑制剂，可阻断病毒粒子的肝细胞进入途径，即肝钠/牛磺胆酸盐协同转运多肽 (NTCP) 受体。它可用于 HBV 和 HDV 感染研究。
T15030	CycLuc1	Others	Others
	CycLuc1 是一种荧光素酶底物，具有血脑屏障渗透性。
T31145	CycLuc3 Cyc Luc 3,Cyc-Luc-3
	CycLuc3 is a type of mutant firefly luciferase variant with enhanced light emission.
T29611	Acluracil
	Acluracil is a biochemical.
T31143	CycLuc12 CycLuc-12,CycLuc 12
	CycLuc12 is a cyclic alkylaminoluciferin substrate for firefly luciferase.
T130746	Clusiacyclol A

T31146	CycLuc7 CycLuc 7,CycLuc-7
	CycLuc7 is a cyclic alkylaminoluciferin substrate for firefly luciferase.
T80065	Calcicludine	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Calcicludine是Dendroaspis angusticeps产毒蛋白，针对高电压激活的calcium channel（特别是L型）有抑制作用，IC50为88 nM，影响兴奋性突触传递。
T76695	Oleclumab
	Oleclumab (MEDI9447) 是一种人 IgG1λ 抗CD73单克隆抗体，可抑制CD73功能。Oleclumab 具有抗肿瘤活性。
T31144	CycLuc2 CycLuc 2,CycLuc-2
	CycLuc2 is a cyclic alkylaminoluciferin substrate for firefly luciferase. CycLuc2 emits 4.7-fold more light than aminoluciferin, and 2.6-fold more light than D-luciferin.
T35373	Bulevirtide (Myrcludex B) Bulevirtide (Myrcludex B),MyrB	Others	Others
	Bulevirtide (Myrcludex B) 是一种牛磺胆酸钠共转运多肽 (sodium-taurocholate co-transporting polypeptide, NTCP) 受体抑制剂，IC50 为 80 pM 左右，能在远低于阻断胆盐转运所需的浓度时使 NTCP 功能失活。
T80614	Serclutamab DC-1630423,PR-1594407	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Serclutamab是一种针对EGFR的IgG1-κ型人源化嵌合抗体，主要通过CHO（中国仓鼠卵巢）细胞进行表达。
T26607	AM-0687 AM 0687
	AM-0687 is a potent and selective PI3Kδ inhibitor. AM-0687 has Cellular potency: pAKT IC50 = 0.7 nM; HWB, u (pAKT) IC 50 = 4.6 nM. Rat KLH: IgG ED50 -= 0.026 mg/kg; IgM ED50 = 0.016 mg/kg. Rat PK Clu = 2.3 L/hr/kg.
T26608	AM-1430 AM1430
	AM-1430 is a potent and selective PI3Kδ inhibitor. AM-1430 has cellular potency: pAKT IC50 = 0.8 nM; HWB,u (pAKT) IC 50 = 7.7 nM. Rat KLH: IgG ED50 -= 0.016 mg/kg; IhM ED50 = 0.015 mg/kg. Rat PK Clu = 1.7 L/hr/kg.

化合物

Bulevirtide (Myrcludex B) acetate

Cat.No: T35373L

Target: HBV

Cat.No: T15030

Target: Others

Cat.No: T31145

Synonym: Cyc Luc 3,Cyc-Luc-3

Cat.No: T29611

Cat.No: T31143

Synonym: CycLuc-12,CycLuc 12

Clusiacyclol A

Cat.No: T130746

Cat.No: T31146

Synonym: CycLuc 7,CycLuc-7

Cat.No: T80065

Target: Calcium Channel

Cat.No: T76695

Cat.No: T31144

Synonym: CycLuc 2,CycLuc-2

Bulevirtide (Myrcludex B)

Cat.No: T35373

Synonym: Bulevirtide (Myrcludex B),MyrB

Target: Others

Cat.No: T80614

Synonym: DC-1630423,PR-1594407

Target: EGFR

Cat.No: T26607

Synonym: AM 0687

Cat.No: T26608

Synonym: AM1430

Cat. No.	Product Name	Target	Signaling Pathways
T20578	Maclurin Fustic extract,Morintannic acid,NSC 83240	Free radical scavengers; Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
	Maclurin (NSC-83240) 是桑枝的酚类成分，具有抗转移作用。 Maclurin 可有效防止 OH 诱导的 DNA 和 MSCs 损伤，可用于预防多种疾病或 MSCs 移植的研究。
TN5912	Macluraxanthone 3-Hydroxyblancoxanthone	Antioxidant; TNF	Apoptosis; oxidation-reduction
	Macluraxanthone (3-Hydroxyblancoxanthone) 具有许多生物活性，包括抗胆碱酯酶、抗氧化、抗癌、抗疟疾、抗炎和免疫调节作用。Macluraxanthone 通过增加表达CD86的巨噬细胞的百分比，同时减少其CD14、CD11b 和CD80的表达，来促进M1类促炎症巨噬细胞的极化。Macluraxanthone 在促炎症刺激物脂多糖的存在下明显减少了TNF-α和IL-10细胞因子的产生。

天然产物

Cat.No: T20578

Synonym: Fustic extract,Morintannic acid,NSC 83240

Target: Free radical scavengers, Reactive Oxygen Species

Macluraxanthone

Cat.No: TN5912

Synonym: 3-Hydroxyblancoxanthone

Target: Antioxidant, TNF

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01691	Clusterin Protein, Human, Recombinant (CLU34, His) SGP-2,AAG4,KUB1,CLI,CLU2,TRPM2,APO-J,SP-40,CLU<...	Human	HEK293 Cells
	Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.
TMPJ-00279	Clusterin Protein, Human, Recombinant (His) Clusterin,Ku70-Binding Protein 1,Apo-J,Testosterone...	Human	HEK293 Cells
	Clusterin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-40 KDa and the accession number is P10909.
TMPY-06908	Clusterin Protein, Human, Recombinant (sCLU, His) KUB1,SP-40,TRPM-2,SGP2,CLI,TRPM2,APOJ,NA1/NA2,CLU1,...	Human	HEK293 Cells
	Clusterin Protein, Human, Recombinant (sCLU, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.51 kDa and the accession number is NP_001822.3.
TMPJ-00278	Clusterin Protein, Human, Recombinant (hFc & His) CLU,NA1/NA2,TRPM-2,40,Apo-J,Clusterin,Comp...	Human	HEK293 Cells
	Clusterin Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is (33-45) and (60-85) KDa and the accession number is P10909.
TMPY-01694	Clusterin Protein, Mouse, Recombinant (His) SP-40,AI893575,Sgp-2,clusterin,Sugp-2,Cli,ApoJ,D14U...	Mouse	HEK293 Cells
	Clusterin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.8 kDa and the accession number is Q06890.
TMPJ-01134	CLUL1 Protein, Human, Recombinant (His) CLUL1,Clusterin-Like Protein 1,Retinal-Spe...	Human	HEK293 Cells
	Clusterin-Like Protein 1 (CLUL1) is a secreted protein that belongs to the clusterin family. CLUL1 is synthesized as a 466 amino acid precursor that contains a 20 amino acid signal sequence, and a 446 amino acid mature chain. CLUL1 is expressed predominantly by cone photoreceptors of the retina. It has been shown that CLUL1 expression is down-regulated in some forms of retinal disease.
TMPY-06211	Clusterin Protein, Chinese hamster, Recombinant (His) clusterin	Chinese hamster	CHO Cells
	Clusterin Protein, Chinese hamster, Recombinant (His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 50.9 kDa and the accession number is G3HNJ3-1.

重组蛋白

Clusterin Protein, Human, Recombinant (CLU34, His)

Cat.No: TMPY-01691

Species: Human

Expression System: HEK293 Cells

Clusterin Protein, Human, Recombinant (His)

Cat.No: TMPJ-00279

Species: Human

Expression System: HEK293 Cells

Clusterin Protein, Human, Recombinant (sCLU, His)

Cat.No: TMPY-06908

Species: Human

Expression System: HEK293 Cells

Clusterin Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00278

Species: Human

Expression System: HEK293 Cells

Clusterin Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01694

Species: Mouse

Expression System: HEK293 Cells

CLUL1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01134

Species: Human

Expression System: HEK293 Cells

Clusterin Protein, Chinese hamster, Recombinant (His)

Cat.No: TMPY-06211

Species: Chinese hamster

Expression System: CHO Cells

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