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Search Results for " cd137 "
Targets Recommended: TNF

6

抑制剂 & 化合物

26

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T76705 Utomilumab

PF 05082566,PF-2566

 TNF Apoptosis
Utomilumab (PF 05082566) 是一种人源化靶向T 细胞共刺激受体4-1BB/CD137的 IgG2 抗体，也是一种 4-1BB/CD137 激动剂。Utomilumab 具有抗肿瘤活性，可用于研究晚期恶性肿瘤患者。
T77367 Urelumab

BMS-663513,BMS-66513

 Others Others
Urelumab(BMS-66513) 是一种人源化的 IgG4 单克隆抗体，常被当作 CD137 激动剂使用。Urelumab 具有潜在的抗肿瘤活性，可增强 T 细胞和自然杀伤细胞对肿瘤细胞的杀伤作用，并增强 Rituximab 的细胞毒性。Urelumab 可用于研究弥漫性大B细胞淋巴瘤 (DLBCL)合滤泡性淋巴瘤 (FL) 等实体瘤相关疾病。
T76734 CTX-471

CTX-471 是 CD137 的全人源单克隆抗体。CTX-471 对重组人、食蟹猴 CD137 和小鼠 CD137 具有结合亲和力，Kd 值分别为 50 nM、61 nM 和 748 nM。CTX-471 可用于免疫调节和癌症的研究。
T74969 Phospholipid PL1

Phospholipid PL1 是一种磷脂衍生的纳米颗粒，能够向 T 细胞传递共刺激受体 mRNA (CD137 或 OX40)。Phospholipid PL1 可诱导多种免疫细胞的激活，包括T 细胞和树突状细胞 (DC)，以增强抗肿瘤免疫反应。
T80590 Cinrebafusp alfa

PRS 343

 EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Cinrebafusp alfa (PRS 343) 是高亲和力 CD137/HER2 双特异性抗体融合蛋白，能结合重组人 HER2 (Kd=0.3 nM) 及人单体 CD137 (4-1BB; Kd=5 nM)。通过 HER2 导向的 4-1BB 聚集激活，Cinrebafusp alfa 促进 T 细胞的共刺激作用，增强 T细胞受体介导的活性，从而有效打击 HER2+ 实体瘤。
T80583 Anti-Mouse 4-1BB Antibody (3H3)

Anti-Mouse4-1BBAntibody为针对小鼠4-1BB的IgG2a类抗体抑制剂，源自宿主Rat。

化合物

Utomilumab
Cat.No: T76705
Synonym: PF 05082566,PF-2566
Target: TNF
Urelumab
Cat.No: T77367
Synonym: BMS-663513,BMS-66513
Target: Others
CTX-471
Cat.No: T76734
Synonym:
Target:
Phospholipid PL1
Cat.No: T74969
Synonym:
Target:
Cinrebafusp alfa
Cat.No: T80590
Synonym: PRS 343
Target: EGFR
Anti-Mouse 4-1BB Antibody (3H3)
Cat.No: T80583
Synonym:
Target:
Species：
Human (10)
Mouse (8)
Cynomolgus (3)
Canine (2)
Cynomolgus,Rhesus (2)
Rhesus (1)
Expression System：
HEK293 Cells (26)
Tag：
C-His (9)
C-hFc (6)
C-hFc-Avi (3)
C-His-Avi (2)
C-6xHis (1)
C-6xHis-Avi (1)
C-Avi-6xHis (1)
C-hFc-6xHis (1)
C-rFc (1)
His, Avi (1)
Cat. No. Product Name Species Expression System
TMPY-01743 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His)

4-1BB,tumor necrosis factor receptor superfamily, member 9,<...

 Human HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.8 kDa and the accession number is Q07011.
TMPY-05376 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc)

4-1BB,tumor necrosis factor receptor superfamily, member 9,<...

 Human HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44 kDa and the accession number is Q07011.
TMPY-05767 4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His)

tumor necrosis factor receptor superfamily, member 9,AA40849...

 Mouse HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.00 kDa and the accession number is P20334.
TMPY-05594 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi), Biotinylated

CDw137,CD137,4-1BB,tumor...

 Human HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 45.8 kDa and the accession number is Q07011.
TMPY-06528 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (soluble CD137, His)

tumor necrosis factor receptor superfamily, member 9,4-1BB,<...

 Human HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (soluble CD137, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.70 kDa and the accession number is Q07011.
TMPJ-00145 4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (hFc)

Tumor necrosis factor receptor superfamily member 9,Tnfrsf9,...

 Mouse HEK293 Cells
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells...
TMPY-06382 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His & Avi), Biotinylated

tumor necrosis factor receptor superfamily, member 9,4-1BB,I...

 Human HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 20.54 kDa and the accession number is NP_001552.2.
TMPY-02330 4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, hFc)

Cd137,A930040I11Rik,tumor necrosis factor ...

 Mouse HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47 kDa and the accession number is Q8R037.
TMPY-06279 4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His), Biotinylated

Cd137,tumor necrosis factor receptor super...

 Mouse HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.00 kDa and the accession number is P20334.
TMPY-05105 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His), Biotinylated

CDw137,ILA,4-1BB,CD137,t...

 Human HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.7 kDa and the accession number is Q07011.
TMPY-04995 4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, rFc)

A930040I11Rik,tumor necrosis factor receptor superfamily, me...

 Mouse HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 46.1 kDa.
TMPY-05031 4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, His)

CDw137,4-1BB,AI325004,A930040I11Rik,Cd...

 Mouse HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.5 kDa and the accession number is Q8R037.
TMPK-00147 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi)

T cell antigen ILA,ILA,4-1BB ligand receptor,FLJ43501,TNFRSF...

 Human HEK293 Cells
4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with...
TMPJ-00142 4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His)

CDw137,ILA,4-1BB ligand receptor,T-cell an...

 Cynomolgus HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 26-35 KDa and the accession number is A9YYE7.
TMPJ-00141 4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc)

4-1BB ligand receptor,CD137,CDw

Cynomolgus HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60 KDa and the accession number is A9YYE7.
TMPJ-00140 4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated

CD137,CDw137,4-1BB ligan...

 Cynomolgus HEK293 Cells
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation. 4-1BB/CD137/TNFRSF9 Pro...
TMPY-06794 4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-187, His & Avi), Biotinylated

tumor necrosis factor receptor superfamily, member 9,AA40849...

 Mouse HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-187, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 20.81 kDa and the accession number is NP_001070977.1.
TMPY-05504 4-1BB/CD137/TNFRSF9 Protein, Rhesus, Recombinant (His), Biotinylated

tumor necrosis factor receptor superfamily, member 9

 Rhesus HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Rhesus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.7 kDa and the accession number is XP_005544945.1&NP_001253057.1.
TMPJ-00143 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, His & Avi), Biotinylated

ILA,4-1BB ligand receptor,T-cell antigen 4-1BB homolog,C...

 Human HEK293 Cells
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation. 4-1BB/CD137/TNFRSF9 Pro...
TMPY-06329 4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-211, His&AVI), Biotinylated

CDw137,AI325004,Cd137,Ly...

 Mouse HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-211, His&AVI), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.32 kDa and the accession number is NP_001070976.1.
TMPJ-00144 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His)

CD137,4-1BB ligand receptor,T-cell antigen...

 Human HEK293 Cells
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation. 4-1BB/CD137/TNFRSF9 Pro...
TMPK-00148 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, hFc & Avi), Biotinylated

TNFRSF9,FLJ43501,4-1BB,4-1BB ligand receptor,ILA,CD...

 Human HEK293 Cells
4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, hFc & Avi), Biotinylated is expressed in HE...
TMPY-00230 4-1BB/CD137/TNFRSF9 Protein, Canine, Recombinant (hFc)

tumor necrosis factor receptor superfamily, member 9

 Canine HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.9 kDa and the accession number is XP_850336.1.
TMPY-03773 4-1BB/CD137/TNFRSF9 Protein, Canine, Recombinant (His)

tumor necrosis factor receptor superfamily, member 9

 Canine HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.4 kDa and the accession number is XP_850336.1.
TMPY-04719 4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Rhesus, Recombinant (hFc)

tumor necrosis factor receptor superfamily, member 9

 Cynomolgus,Rhesus HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44 kDa and the accession number is XP_005544945.1&NP_001253057.1.
TMPY-04720 4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Rhesus, Recombinant (His)

tumor necrosis factor receptor superfamily, member 9

 Cynomolgus,Rhesus HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.7 kDa and the accession number is XP_005544945.1&NP_001253057.1.

重组蛋白

4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His)
Cat.No: TMPY-01743
Species: Human
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05376
Species: Human
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05767
Species: Mouse
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05594
Species: Human
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (soluble CD137, His)
Cat.No: TMPY-06528
Species: Human
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00145
Species: Mouse
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06382
Species: Human
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, hFc)
Cat.No: TMPY-02330
Species: Mouse
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-06279
Species: Mouse
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05105
Species: Human
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, rFc)
Cat.No: TMPY-04995
Species: Mouse
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, His)
Cat.No: TMPY-05031
Species: Mouse
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi)
Cat.No: TMPK-00147
Species: Human
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00142
Species: Cynomolgus
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-00141
Species: Cynomolgus
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00140
Species: Cynomolgus
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-187, His & Avi), Biotinylated
Cat.No: TMPY-06794
Species: Mouse
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Rhesus, Recombinant (His), Biotinylated
Cat.No: TMPY-05504
Species: Rhesus
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, His & Avi), Biotinylated
Cat.No: TMPJ-00143
Species: Human
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-211, His&AVI), Biotinylated
Cat.No: TMPY-06329
Species: Mouse
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00144
Species: Human
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, hFc & Avi), Biotinylated
Cat.No: TMPK-00148
Species: Human
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-00230
Species: Canine
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Canine, Recombinant (His)
Cat.No: TMPY-03773
Species: Canine
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Rhesus, Recombinant (hFc)
Cat.No: TMPY-04719
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Rhesus, Recombinant (His)
Cat.No: TMPY-04720
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
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