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Cat. No.	Product Name	Target	Signaling Pathways
T38161	STING Agonist C11 STING Agonist C11
	STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway.1 It induces secretion of type I IFN from THF and MM6 cells when used at a concentration of 50 μM. STING agonist C11 induces phosphorylation of IFN regulatory factor 3 (IRF3) and increases expression of IFIT1 and viperin, but not IL-1β, IL-6, or IL-8 in THF cells in a STING-dependent manner. It reduces viral titers of chikungunya, Venezuelan equine encephalitis, o'nyong-nyong, Mayaro, and Ross River viruses gro...
T40419	IRES-C11 IRES-C11	c-Myc	Cell Cycle/Checkpoint
	IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction between heterogeneous nuclear ribonucleoprotein A1, a trans-acting factor required for c-MYC IRES activity, and its corresponding IRES. Notably, IRES-C11 does not inhibit the IRES activity of BAG-1, XIAP, and p53.
T39652	BODIPY 581/591 C11 BODIPY 581/591 C11
	C11-BODIPY581/591 is a fluorescent ratio-probe of lipid oxidation . C11-BODIPY581/591 is often used for indexing lipid peroxidation and antioxidant efficacy in model membrane systems and living cells. C11-BODIPY581/591 is applied in the quantitation of ferroptosis.
T13773	Mito-apocynin (C11)	Others	Others
	Mito-apocynin (C11)是一种线粒体靶向抗氧化剂，通过靶向和中和细胞呼吸过程中产生的活性氧（ROS）发挥作用。三苯基溴化鏻已被发现能有效预防线粒体功能障碍，线粒体功能障碍是衰老过程和各种疾病的主要原因。它具有抗炎、抗凋亡和抗氧化活性。
T77971	Pomalidomide-C11-NH2 hydrochloride
	Pomalidomide-C11-NH2 hydrochloride 是一款以 Pomalidomide 为基础的 E3 泛素连接酶 cereblon (CRBN) 配体，主要应用于募集 cereblon 蛋白。该化合物能够借助 linker 结构与蛋白质配体相连，从而构建 PROTAC 分子。
T77981	Pomalidomide-5-C11-NH2 hydrochloride
	Pomalidomide-5-C11-NH2 hydrochloride 是一款基于 Pomalidomide 的 cereblon (CRBN) E3 泛素连接酶配体，能够招募 cereblon 蛋白。通过 linker 结构，该化合物可用于构建 PROTAC，实现其与蛋白质配体的连接。
T77958	Thalidomide-5-O-C11-NH2 hydrochloride
	Thalidomide-5-O-C11-NH2 hydrochloride是一款基于Thalidomide的cereblon配体，能够招募CRBN蛋白。该化合物通过linker与靶向蛋白配体结合，用于构建PROTAC分子，如THAL-SNS-032。
T77962	Thalidomide-4-O-C11-NH2 hydrochloride
	Thalidomide-4-O-C11-NH2 hydrochloride是Thalidomide衍生的cereblon配体，能够募集CRBN蛋白。该化合物能够利用linker与目标蛋白配体结合，进而形成PROTAC分子，如THAL-SNS-032。
T10640	C-11	Others	Others
	C-11 is a tubulin inhibitor and acts as an ADC cytotoxin with cytotoxicity for carcinoma cell lines.
T32696	Levetimide C-11
	Levetimide C-11 is a radiotracer.
T32289	jhu-75528c-11 JHU75528 C-11,11c-Omar,JHU 75528 C-11
	JHU-75528 C-11 can be used as a Radiotracer for PET Imaging of CB1 Cannabinoid Receptors.
T84314	BFC1108

T9083	TC11 CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11	BCL; Caspase; CDK	Apoptosis; Cell Cycle/Checkpoint; Proteases/Proteasome
	TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) 是一种有效的肿瘤细胞增殖抑制剂，并通过激活 caspase-3、8 和 9 诱导细胞凋亡。在长时间有丝分裂阻滞期间，它诱导 MCL1降解导致凋亡。它作为苯酞酰亚胺衍生物在结构上与免疫调节药物相关。
T23601	ABC1183 ABC 1183,ABC-1183	GSK-3; CDK	Cell Cycle/Checkpoint; PI3K/Akt/mTOR signaling; Stem Cells
	ABC1183是一种抑制GSK3α， GSK3β和CDK9的新型二氨基噻唑。ABC1183通过诱导G2/M 阻滞和改变GSK3、糖原合成酶、β-catenin 磷酸化和MCL1表达降低细胞存活率来抑制多种癌细胞株的生长，并具有口服活性。
T74400	TC113
	TC113是一种与c(RGDyK)偶联的Gemcitabine。它通过整合素αvβ3可被A549细胞内化。此外，TC113对WM266.4和A549细胞表现出显著的抗增殖效果。
T78179	NH2-UAMC1110 TFA
	NH2-UAMC1110 TFA 是 UAMC1110 的一个衍生物，用于合成 FAPI-QS。UAMC1110 是成纤维细胞激活蛋白（FAP）的抑制剂，而 FAPI-QS 作为螯合剂，用于制备特异性高、剂量大的放射性示踪剂，适用于肿瘤的诊断与治疗。
T73591	C11237
	C11237 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T73591，CAS号为 1806-98-0。
T61177	NSC114126
	NSC114126 is a highly effective and orally bioavailable inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR-TK). This compound exhibits robust antiproliferative properties, making it a promising candidate for further investigation in the field of cancer research [1].
T25855	NC1153 CN-1153,NC-1153,NC 1153,CN 1153,CN1153
	NC1153 is a blocker of IL-2-induced activation of JAK3 and its downstream substrates STAT5a/b. It promotes long-term allograft survival and sparing the recipient from multiple toxicities.
T69853	AR-C117977
	AR-C117977 is a potent MCT1 inhibitor, which can reduce vimmune responses both in vitro and in vivo, maintains long-term graft survival, and induces operational tolerance.
T41061	Histone H3 (116-136), C116-136 Histone H3 (116-136), C116-136
	Histone H3 (116-136), C116-136 is a peptide consisting of amino acids 116 to 136, which spans the C-terminus of histone H3.
T77815	EC1167 hydrochloride
	EC1167 hydrochloride为EC1169的linker，后者是针对前列腺特异性膜抗原的小管溶解蛋白偶联物。EC1169 hydrochloride展现了对治疗复发性转移性去势性前列腺癌（MCRPC）的研究潜力。
T24434	MCC1189 MCC 1189,MCC-1189
	MCC1189 is a first-in-class MFS efflux pump CaMdr1p inhibitor.
TP2375	C112 Peptide Ile-arg-pro-val-gln
	C112 Peptide is a novel peptide.
T29261	(S)-Desmethyl-NNC112 (+)-Desmethyl-NNC112
	(S)-Desmethyl-NNC112 is a PET precursor for NNC112.
T70821	FC11409B
	FC11409B is a CAIX inhibitor, inhibiting breast cancer invasion and metastasis.
T24549	NSC114792 NSC-114792,NSC 114792
	NSC114792 is a selective JAK3 inhibitor.
T12260	NSC117079	Others	Others
	NSC117079 is an inhibitor of PHLPP.
TP2374	C111 Peptide Gly-val-tyr-pro-his-lys
	C111 Peptide is a peptide.
T17930	EC1167	Others	Others
	EC1169 is a targeted tubulysin conjugate that utilizes EC1167 as its linker. This compound shows promise in the treatment of recurrent metastatic, castration-resistant prostate cancer (MCRPC)[1].
T62835	Antitumor agent-54
	Antitumor agent-54 (Compound C11) 是一种 14-3-3η 蛋白抑制剂 (KD: 35 μM)。Antitumor agent-54 能够抑制几种典型的人肝癌细胞系。Antitumor agent-54 可以将细胞周期阻滞在 G1-S 期，并诱导细胞凋亡，表现出良好的代谢稳定性。
T37879	N-undecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gener...
T36384	DL-Tyrosine-13C9,15N L-Tyrosine-13C9,15N
	L-Tyrosine-13C9,15N is intended for use as an internal standard for the quantification of L-tyrosine by GC- or LC-MS. L-Tyrosine is a non-essential amino acid.1It is produced by hydroxylation of phenylalanine by phenylalanine hydroxylase but can also be obtained from dietary sources or degradation of endogenous proteins, resulting in L-tyrosine release.1,2L-Tyrosine is a precursor in the biosynthesis of catecholamine neurotransmitters, melanins, and thyroid hormones.3Plasma, skeletal muscle, and...

化合物

STING Agonist C11

Cat.No: T38161

Synonym: STING Agonist C11

Cat.No: T40419

Synonym: IRES-C11

Target: c-Myc

BODIPY 581/591 C11

Cat.No: T39652

Synonym: BODIPY 581/591 C11

Mito-apocynin (C11)

Cat.No: T13773

Target: Others

Pomalidomide-C11-NH2 hydrochloride

Cat.No: T77971

Pomalidomide-5-C11-NH2 hydrochloride

Cat.No: T77981

Thalidomide-5-O-C11-NH2 hydrochloride

Cat.No: T77958

Thalidomide-4-O-C11-NH2 hydrochloride

Cat.No: T77962

Cat.No: T10640

Target: Others

Levetimide C-11

Cat.No: T32696

Cat.No: T32289

Synonym: JHU75528 C-11,11c-Omar,JHU 75528 C-11

Cat.No: T84314

Cat.No: T9083

Synonym: CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11

Target: BCL, Caspase, CDK

Cat.No: T23601

Synonym: ABC 1183,ABC-1183

Target: GSK-3, CDK

Cat.No: T74400

NH2-UAMC1110 TFA

Cat.No: T78179

Cat.No: T73591

Cat.No: T61177

Cat.No: T25855

Synonym: CN-1153,NC-1153,NC 1153,CN 1153,CN1153

Cat.No: T69853

Histone H3 (116-136), C116-136

Cat.No: T41061

Synonym: Histone H3 (116-136), C116-136

EC1167 hydrochloride

Cat.No: T77815

Cat.No: T24434

Synonym: MCC 1189,MCC-1189

Cat.No: TP2375

Synonym: Ile-arg-pro-val-gln

(S)-Desmethyl-NNC112

Cat.No: T29261

Synonym: (+)-Desmethyl-NNC112

Cat.No: T70821

Cat.No: T24549

Synonym: NSC-114792,NSC 114792

Cat.No: T12260

Target: Others

Cat.No: TP2374

Synonym: Gly-val-tyr-pro-his-lys

Cat.No: T17930

Target: Others

Antitumor agent-54

Cat.No: T62835

N-undecanoyl-L-Homoserine lactone

Cat.No: T37879

DL-Tyrosine-13C9,15N

Cat.No: T36384

Synonym: L-Tyrosine-13C9,15N

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