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抑制剂 & 化合物

19

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T78292 Ifinatamab

Anti-Human B7-H3

Ifinatamab为一抗人B7同源3蛋白(HumanB7-H3)的单克隆免疫球蛋白G1-kappa,属于糖型α免疫调节剂类。
T9901A-002 Enoblituzumab

MGA271,TJ-271

Others Others
Enoblituzumab 是一种人源化 IgG1κ 单克隆抗体,可以识别人 B7-H3 蛋白 ,可用于研究非小细胞肺癌 (NSCLC)等实体肿瘤。
T78274 Omburtamab

Omburtamab是一款针对CD276(亦称为B7-H3)的单克隆抗体,后者为在人类实体肿瘤中表达的B7/CD28免疫球蛋白家族成员。此抗体能够结合肿瘤组织,被应用于多种癌症的研究中。
T77909 Mirzotamab

Mirzotamab clezutoclax(ABBV-155)是一种IgG1κ型靶向CD276/B7-H3的抗体偶联物(ADC),通过与BCL抑制剂Clezutoclax结合而构成。该化合物用于参与针对复发/难治性实体瘤的紫杉烷相关研究。
T77104 Obrindatamab

Obrindatamab 是一种人源化抗 B7-H3/CD3双特异性抗体。Obrindatamab 结合 B7-H3和 CD3,从而介导针对表达 B7-H3的癌细胞的重定向细胞毒性 T 淋巴细胞 (CTL) 活性。Obrindatamab 可用于癌症研究。
T77905 Vobramitamab

AEX-4089

Vobramitamab为针对人源B7-H3的单克隆抗体(mAb)。该抗体通过一个可切割的连接物与前药seco-DUBA相结合,构成一种抗体-药物偶联物(ADC)名为MGC018。

化合物

Ifinatamab
Cat.No: T78292
Synonym: Anti-Human B7-H3
Target:
Enoblituzumab
Cat.No: T9901A-002
Synonym: MGA271,TJ-271
Target: Others
Omburtamab
Cat.No: T78274
Synonym:
Target:
Mirzotamab
Cat.No: T77909
Synonym:
Target:
Obrindatamab
Cat.No: T77104
Synonym:
Target:
Vobramitamab
Cat.No: T77905
Synonym: AEX-4089
Target:
Cat. No. Product Name Species Expression System
TMPY-02031 B7-H3 Protein, Human, Recombinant (His)

CD276 molecule,B7-H3,4Ig-B7-H...

Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q5ZPR3-1.
TMPY-04262 B7-H3 Protein, Human, Recombinant (His), Biotinylated

B7H3,4Ig-B7-H3,CD276 mol...

Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q5ZPR3-1.
TMPY-05641 B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated

4Ig-B7-H3,B7-H3,B7

Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 49.8 kDa and the accession number is Q5ZPR3.
TMPY-00643 B7-H3 Protein, Human, Recombinant (hFc)

B7RP-2,B7H3,B7-H3

Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.3 kDa and the accession number is Q5ZPR3-1.
TMPK-00314 B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)

B7-H3,PSEC0249,PRO352, 4Ig-B7-

Human HEK293 Cells
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted m...
TMPY-05279 B7-H3 Protein, Human, Recombinant (hFc), Biotinylated

B7RP-2,B7-H3,CD276 molecule,B...

Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q5ZPR3-1.
TMPY-06581 B7-H3 Protein, Human, Recombinant (isoform 2, His)

CD276 molecule,B7H3,B7RP-2,4Ig-

Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (isoform 2, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.52 kDa and the accession number is Q5ZPR3-2.
TMPK-00315 B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated

 4Ig-B7-H3,CD276,UNQ309,B7-H3...

Human HEK293 Cells
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. T...
TMPK-01017 B7-H3 Protein, Human, Recombinant (aa 29-245, hFc)

B7H3,B7-H3,B7 h...

Human HEK293 Cells
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (aa 29-245, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weig...
TMPK-01016 B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled

B7H3, UNQ309,PRO352,PSEC0249,B7 h...

Human HEK293 Cells
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular w...
TMPK-01018 B7-H3 Protein, Human, Recombinant (aa 29-245, His)

PRO352,B7H3, UNQ309,PSEC0249,CD276,B7<...

Human HEK293 Cells
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (aa 29-245, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weig...
TMPY-04064 B7-H3 Protein, Mouse, Recombinant (His)

6030411F23Rik,B7RP-2,B7h3,CD276 m...

Mouse HEK293 Cells
B7-H3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.9 kDa and the accession number is A6MDC5.
TMPY-03914 B7-H3 Protein, Rat, Recombinant (hFc)

CD276 molecule

Rat HEK293 Cells
B7-H3 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.6 kDa and the accession number is Q7TPB4.
TMPY-00268 B7-H3 Protein, Cynomolgus, Recombinant (hFc)

CD276 molecule

Cynomolgus HEK293 Cells
B7-H3 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.8 kDa and the accession number is A0A7N9CYV2.
TMPY-04284 B7-H3 Protein, Rat, Recombinant (His)

CD276 molecule

Rat HEK293 Cells
B7-H3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is Q7TPB4.
TMPY-04585 B7-H3 Protein, Cynomolgus, Recombinant (His)

CD276 molecule

Cynomolgus HEK293 Cells
B7-H3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.5 kDa and the accession number is A0A7N9CYV2.
TMPY-05433 B7-H3 Protein, Mouse, Recombinant (hFc)

AU016588,CD276 molecule,B7RP-2,B7h3

Mouse HEK293 Cells
B7-H3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.5 kDa and the accession number is A6MDC5.
TMPY-04279 B7-H3 Protein, Mouse, Recombinant (His), Biotinylated

AU016588,B7RP-2,6030411F23Rik,B7h3

Mouse HEK293 Cells
B7-H3 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.9 kDa and the accession number is A6MDC5.
TMPY-01648 TREML2 Protein, Human, Recombinant (His)

TLT2,dJ238O23.1,triggering receptor expressed on myeloid cel...

Human HEK293 Cells
Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like) domain. TREML2 is detected in cultured B cells, T cell leukemia and monocyte leukemia. TREML2 is expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation. TREML2 is a cell surface receptor that may play a role in the innate and adaptive immune respons...

重组蛋白

B7-H3 Protein, Human, Recombinant (His)
Cat.No: TMPY-02031
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-04262
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05641
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00643
Species: Human
Expression System: HEK293 Cells
B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00314
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05279
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (isoform 2, His)
Cat.No: TMPY-06581
Species: Human
Expression System: HEK293 Cells
B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00315
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (aa 29-245, hFc)
Cat.No: TMPK-01017
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled
Cat.No: TMPK-01016
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (aa 29-245, His)
Cat.No: TMPK-01018
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04064
Species: Mouse
Expression System: HEK293 Cells
B7-H3 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03914
Species: Rat
Expression System: HEK293 Cells
B7-H3 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-00268
Species: Cynomolgus
Expression System: HEK293 Cells
B7-H3 Protein, Rat, Recombinant (His)
Cat.No: TMPY-04284
Species: Rat
Expression System: HEK293 Cells
B7-H3 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-04585
Species: Cynomolgus
Expression System: HEK293 Cells
B7-H3 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05433
Species: Mouse
Expression System: HEK293 Cells
B7-H3 Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-04279
Species: Mouse
Expression System: HEK293 Cells
TREML2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01648
Species: Human
Expression System: HEK293 Cells
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