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Search Results for " antidiarrheal "

10

抑制剂 & 化合物

3

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T1176	Racecadotril Acetorphan,消旋卡多曲	Neprilysin; Proteasome	Metabolism; Proteases/Proteasome; Ubiquitination
	Racecadotril (Acetorphan) 是一种中性内肽酶 (NEP) 抑制剂，具有止泻作用。Racecadotril 及其活性代谢物 Thiorphan 抑制小鼠脑中纯化的NEP 活性，Ki 分别为 4500 和 6.1 nM。
T25719	Lidamidine Lidamidina,Lidamidinum,利达脒	Others	Others
	Lidamidine (Lidamidinum) 是一种临床有效的止泻化合物，可抑制肠道分泌，减少肠道转运，并抑制平滑肌收缩。
T1563	Nifuroxazide Diarlidan,硝呋齐特,Nifuroxazid,Dicoferin,硝呋酚酰肼	Antibacterial; Antibiotic; STAT	JAK/STAT signaling; Microbiology/Virology; Stem Cells
	Nifuroxazide (Diarlidan) 是STAT3抑制剂，具有抗转移和抗癌活性。
T0209	Loperamide hydrochloride Loperamide HCl,R-18553 (hydrochloride),ADL 2-1294,盐酸洛哌丁胺	Opioid Receptor; Autophagy	Autophagy; Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Loperamide hydrochloride (ADL 2-1294) 是一种合成的哌啶衍生物和阿片样物质激动剂，具有止泻活性。
T25430	Fluperamide R18910,R 18910,R-18910
	Fluperamide is an antidiarrheal.
T30915	CI 750 CI750
	CI-750 is a novel antidiarrheal agent.
T25753	Loperamide oxide R 58425,R58425,R-58425
	Loperamide oxide is a prodrug of loperamide, the effective antidiarrheal.
T30964	Clamoxyquin hydrochloride Clamoxyquin HCl,Clamoxyquin dihydrochloride,CN-17,900-2B,Clamoxyquine hydrochloride,CN 17900-2 B
	Clamoxyquin hydrochloride is an anti ameba and antidiarrheal drug. It has been used as a veterinary drug to treat salmon infected with brain armyworm.
T71161	Thiorphan disulfide
	Thiorphan disulfide is an impurity of Racecadotril -- an antidiarrheal and enkephalinase inhibitor that reduces the amount of water and electrolytes absorbed into the intestine.
T25206	Casokefamide beta Casomorphin 4027
	Casokefamide is a peripherally-specific, synthetic opioid pentapeptide. It was derived from the β-casomorphin sequence and designed with the intention of improving resistance to digestive enzymes so that it could be used as an antidiarrheal medicine.

化合物

Cat.No: T1176

Synonym: Acetorphan,消旋卡多曲

Target: Neprilysin, Proteasome

Cat.No: T25719

Synonym: Lidamidina,Lidamidinum,利达脒

Target: Others

Cat.No: T1563

Synonym: Diarlidan,硝呋齐特,Nifuroxazid,Dicoferin,硝呋酚酰肼

Target: Antibacterial, Antibiotic, STAT

Loperamide hydrochloride

Cat.No: T0209

Synonym: Loperamide HCl,R-18553 (hydrochloride),ADL 2-1294,盐酸洛哌丁胺

Target: Opioid Receptor, Autophagy

Cat.No: T25430

Synonym: R18910,R 18910,R-18910

Cat.No: T30915

Synonym: CI750

Loperamide oxide

Cat.No: T25753

Synonym: R 58425,R58425,R-58425

Clamoxyquin hydrochloride

Cat.No: T30964

Synonym: Clamoxyquin HCl,Clamoxyquin dihydrochloride,CN-17,900-2B,Clamoxyquine hydrochloride,CN 17900-2 B

Thiorphan disulfide

Cat.No: T71161

Cat.No: T25206

Synonym: beta Casomorphin 4027

Cat. No.	Product Name	Target	Signaling Pathways
TN5369	Dehydroleucodine Dehydroleucodin
	Dehydroleucodine has antidiarrheal, anti-inflammatory, anti-microbial, embryotoxicity, gastric cytoprotective, anti-cancer activities. Dehydroleucodine has an important inhibitory effect in cellular pathways regulating adipocyte differentiation by modulat
TN5147	Tilifodiolide	IL Receptor; TNF; GABA Receptor	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience
	Tilifodiolide exerts in vitro and in vivo anti-inflammatory activity and in vivo antinociceptive effects. Tilifodiolide exerted antidiarrheal activity by decreasing the intestinal fluid accumulation and vasorelaxant effects mediated by nitric oxide and cyclic guanosine monophosphate, it also showed anxiolytic and antidepressant effects by the partial involvement of gamma-Aminobutyric acid (GABA) receptors and the possible participation of α2-adrenoreceptors, respectively.
TN1641	(-)-Fenchone	Others; Antioxidant; Antifungal	Microbiology/Virology; Others; oxidation-reduction
	(-)-Fenchone 是一种双环单萜类化合物，广泛分布于植物中，可从Foeniculum vulgare 和Peumus boldus 中提取。(-)-Fenchone 具有广泛的生物活性，包括抗氧化，伤口愈合，止泻，抗真菌，抗伤害感受和支气管扩张剂活性。(-)-Fenchone 是一种潜在的抗肿瘤化合物。

天然产物

Dehydroleucodine

Cat.No: TN5369

Synonym: Dehydroleucodin

Cat.No: TN5147

Target: IL Receptor, TNF, GABA Receptor

Cat.No: TN1641

Target: Others, Antioxidant, Antifungal

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