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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T78248 |
Nesvacumab
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Nesvacumab为全人源IgG1型单克隆抗体,具有高亲和力,可特异性结合并灭活Tie2受体配体Angiopoietin-2(Ang2),与Ang1无结合作用。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN3139 |
5α-Hydroxycostic acid
5alpha-Hydroxycostic acid |
ERK; FAK; Phospholipase; NOS; Akt; Src | Angiogenesis; Cytoskeletal Signaling; Immunology/Inflammation; MAPK; Metabolism; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors |
5alpha-Hydroxycostic acid possesses anti-angiogenic ability by interfering the VEGF- and Ang2-related pathways, and it may be a good drug candidate. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02474 |
ANGPT2/Angiopoietin-2 Protein, Mouse, Recombinant (His)
angiopoietin 2,Agpt2,Ang... |
Mouse | HEK293 Cells |
ANGPT2/Angiopoietin-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.5 kDa and the accession number is B9EHQ4. | |||
TMPY-00664 |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)
Angiopoietin-2,AGPT2,ang... |
Human | HEK293 Cells |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 81.6 kDa and the accession number is O15123-1. | |||
TMPJ-00303 |
ANG2 Protein, Mouse, Recombinant (hFc)
angiopoietin 2,Angiopoietin-2... |
Mouse | HEK293 Cells |
ANG2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is O35608. | |||
TMPJ-01435 |
ANG2 Protein, Rhesus macaque, Recombinant (hFc)
ANG-2,Angiopoietin-2,AGP... |
Rhesus | HEK293 Cells |
ANG2 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is XM_001097949. | |||
TMPY-05360 |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (mFc)
ANG2,AGPT2,Angiopoietin-... |
Human | HEK293 Cells |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 80.3 kDa and the accession number is O15123-1. | |||
TMPY-00083 |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His)
ANG2,angiopoietin 2,AGPT... |
Human | HEK293 Cells |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.8 kDa and the accession number is O15123-1. | |||
TMPY-05259 |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His), Biotinylated
angiopoietin 2,Angiopoietin-2... |
Human | CHO Cells |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His), Biotinylated is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 56.4 kDa and the accession number is O15123-1. | |||
TMPY-06613 |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His & Avi), Biotinylated
ANG2,angiopoietin 2,... |
Human | HEK293 Cells |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.72 kDa and the accession number is NP_001138.1. | |||
TMPK-00303 |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His & Avi)
angiopoietin 2,angiopoietin-2... |
Human | HEK293 Cells |
Angiopoietin-2 (Ang-2; also ANGPT2) is a secreted glycoprotein that plays a complex role in angiogenesis and inflammation. Mature Ang-2 is 478 amino acids in length.Ang2 is widely expressed during development, but it is restricted postnatally to highly angiogenic tissues such as the placenta, ovaries, and uterus. It is particularly abundant in vascular endothelial cells (EC) where it is stored in intracellular Weibel Palade bodies.. | |||
TMPJ-00240 |
CAMK1 Protein, Human, Recombinant (His)
CaM Kinase I Alpha,CaMKI-α,CaM Kinase I,CAMK1,Calcium/Calmod... |
Human | HEK293 Cells |
Calcium/Calmodulin-Dependent Protein Kinase Type 1 (CAMK1) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and CaMK subfamily. CAMK1 contains one protein kinase domain and widely expressed. CAMK1 is phosphorylated by CaMKK1 and CaMKK2 on Thr-177. CAMK1 regulates transcription activators activity, cell cycle, hormone production, cell differentiation, actin filament organization, and neurite outgrowth. CAMK1 plays a role in K+ and ANG2-mediated regulation of the aldo... | |||
TMPY-01217 |
ANGPTL5 Protein, Human, Recombinant (GST)
angiopoietin like 5,ANGPTL5 |
Human | Baculovirus Insect Cells |
The angiopoietins are protein growth factors that promote angiogenesis, the formation of blood vessels from pre-existing blood vessels. There are now four identified angiopoietins: Ang1, Ang2, Ang3, Ang4. In addition, there are a number of proteins that are closely related to angiopoietins (ANGPTL2, ANGPTL3, ANGPTL4, ANGPTL5, ANGPTL6, ANGPTL7). Angiopoietin-like 5 (ANGPTL5) is mainly expressed in adult heart. Like other members of the angiopoietin family, ANGPTL5-deduced protein also has an N-te... |