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Search Results for " acetylcholine bromide "

33

抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T20344	Acetylcholine bromide	Others	Others
	Acetylcholine bromide 是乙酰胆碱的溴化物盐。它是一种神经递质，存在于神经肌肉接头、自主神经节、副交感神经效应器接头、交感神经效应器接头的一个子集以及中枢神经系统的许多部位。
T14345	Atropine methyl bromide 甲溴阿托品,Methylatropine bromide	AChR	Neuroscience
	Atropine methyl bromide (Methylatropine bromide) is a quaternary ammonium salt of atropine, characterized as a muscarinic receptor (mAChR) antagonist. It functions as a mydriatic to dilate the pupil during ophthalmic examination. Compared to atropine, it demonstrates reduced penetration into the central nervous system[1][2]. Its high polarity makes it particularly effective in relieving pyloric spasm in infants.
T9420	prifinium bromide	Others	Others
	Prifinium bromide 是抗胆碱能试剂，能够改善痉挛，具有止吐效果。
T2387	Glycopyrrolate Gastrodyn,Glycopyrronium bromide,Robinul,Glycopyrrolate bromide,格隆溴铵	AChR	Neuroscience
	Glycopyrrolate (Glycopyrrolate bromide) 是一种毒蕈碱拮抗剂，在某些胃肠道疾病中用作解痉剂，并与某些麻醉剂一起减少唾液分泌。
T4997	Umeclidinium bromide 芜地溴铵,GSK573719A	AChR	Neuroscience
	Umeclidinium bromide (GSK573719A) 是mAChR 拮抗剂，作用于克隆的人 M1-M5 mAChRs，Ki 为 0.05 到 0.16 nM。
T6744	Methylbenactyzium Bromide Noinarin,Paragone,Methylbenactyzine Bromide,溴甲贝那替秦,Semulgin,Gastrimade	AChR	Neuroscience
	Methylbenactyzium Bromide (Semulgin) 是毒蕈碱性乙酰胆碱受体抑制剂，是一种抗惊厥药。
T1474	Otilonium bromide Octylonium bromide,奥替溴铵,SP63	Calcium Channel; AChR	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Otilonium bromide (SP63) 是一种抗毒蕈碱药，用作解痉剂。
T0098	Ipratropium bromide monohydrate Ipratropium bromide hydrate,溴化异丙托品单水合物	AChR	Neuroscience
	Ipratropium bromide monohydrate (Ipratropium bromide hydrate) 是一种毒蕈碱拮抗剂，结构上与阿托品相关，但它通常被认为对吸入使用更安全、更有效。它用于各种支气管疾病、鼻炎和抗心律失常。
T0166	Pancuronium dibromide Pancuronium bromide,Pavulon,泮库溴铵	AChR	Neuroscience
	Pancuronium dibromide (Pavulon) 是一种双季基类固醇，是一种神经肌肉松弛剂。它通过与乙酰胆碱竞争 nACh 受体上的结合位点来抑制神经肌肉传递。它还可抑制心脏毒蕈碱受体并具有拟交感神经作用。
T1179	Tiotropium bromide Tiopropium,噻托溴铵,BA679 BR	AChR	Neuroscience
	Tiotropium bromide (BA679 BR) 是一种毒蕈碱乙酰胆碱受体拮抗剂，可阻断乙酰胆碱配体的结合。
T0818	Decamethonium bromide 十烃溴铵,Decacuran,溴化十烃季胺,Syncurine	AChR; AChE	Neuroscience
	Decamethonium bromide (Syncurine) 是神经肌肉阻滞剂和烟碱型 AChR 部分激动剂。
T28827	Sofpironium bromide BBI4000,BBI 4000,BBI-4000	Others; AChR	Neuroscience; Others
	Sofpironium bromide (BBI4000) 是一种抗胆碱能剂，用于研究原发性腋窝多汗症。它对 M1、M2、M4 和 M5 亚型也有很高的亲和力。它通过抑制应用部位外分泌腺中的M3毒蕈碱受体来减少出汗。
T0786	Clidinium bromide 克利溴铵,Ro 2-3773	AChR	Neuroscience
	Clidinium bromide (Ro 2-3773) 是季胺抗毒蕈碱剂，可通过减少胃酸和减慢肠道速度，缓解痉挛和腹部疼痛的症状。
T1006	Propantheline bromide Neopepulsan,溴丙胺太林,Pro-Banthine,Neometantyl	AChR	Neuroscience
	Propantheline bromide (Pro-Banthine) 是一种抗毒蕈碱剂，用于研究多汗症，遗尿，胃肠和膀胱痉挛。
T1594	Vecuronium bromide ORG NC 45,维库溴铵	AChR	Neuroscience
	Vecuronium bromide (ORG NC 45) 是一种合成的中效单季铵盐类固醇和非去极化神经肌肉阻滞剂，具有肌肉松弛活性。
T0287	Hexamethonium Bromide Gangliostat,溴化六甲铵,Simpatoblock,六甲溴铵,Hexamethonium Dibromide	Apoptosis; Dopamine Receptor; AChR	Apoptosis; GPCR/G Protein; Neuroscience
	Hexamethonium Bromide (Hexamethonium Dibromide) 是神经节中神经元型烟碱型 AChR 的特异性拮抗剂。在自发性高血压动物模型中，它能降低其交感神经活动和血压。
T6547	Ipratropium Bromide Sch 1000,异丙托溴铵,Itrop,Atrovent	AChR	Neuroscience
	Ipratropium Bromide (Sch 1000) 是毒蕈碱的受体的拮抗剂，可用于 COPD 和哮喘等研究，对 M1、M2 和 M3 受体的结合的IC50值分别为 2.9、2 和 1.7 nM。
T2555	Aclidinium bromide LAS 34273,LAS-W 330,阿地溴铵	AChR	Neuroscience
	Aclidinium bromide (LAS-W 330) 是长效可吸入型的毒蕈碱拮抗剂，有用于慢性阻塞性肺病 (COPD) 的研究潜力。
T0794	Mepenzolate Bromide Colibantil,Cantil,溴美喷酯,Cantilaque	AChR	Neuroscience
	Mepenzolate Bromide (Colibantil) 是一种可口服的毒蕈碱受体拮抗剂，对hM2R 和hM3R 的Ki 分别为 0.68 和 2.6 nM。它是GPR109A 抑制剂，可用于抑制与肠易激综合征相关的胃肠道过度运动。
T0253	Methscopolamine Methscopolamine bromide,甲溴东莨菪碱,Hyoscine methyl bromide,(-)-Scopolamine methyl bromide	AChR	Neuroscience
	Methscopolamine (Hyoscine methyl bromide) 作为一种天然植物生物碱，是一种毒蕈碱乙酰胆碱受体阻滞剂。
T1220	Ethidium bromide EtBr,Homidium bromide,EB,溴化乙啶	AChR	Neuroscience
	Ethidium bromide (EB) 是一种可用作分子生物实验学中的荧光标记(核酸染色)，如琼脂糖凝胶电泳。Ethidium bromide 的λEx 为300-360 nm,λEm为590 nm。
T12690	Rapacuronium bromide Org 9487	Others	Others
	Rapacuronium bromide is an allosteric muscarinic acetylcholine receptor (mAChR) modulator.
T14206	Ambutonium bromide BL700	Others	Others
	Ambutonium bromide is an antagonist of acetylcholine.
T24057	Fazadinium bromide
	Fazadinium bromide is a muscle relaxant. It acts as a nicotinic acetylcholine receptor antagonist through the neuromuscular blockade.
T19640	Flutropium Bromide Ba598,Ba 598,Flubron,Ba-598
	Flutropium Bromide is a competitive antagonist of acetylcholine. It is used to treat asthma and chronic obstructive pulmonary.
T23961	Dacuronium bromide NB 68,ORG 6368,NB68,Dacuronii bromidum
	Dacuronium bromide is an aminosteroid neuromuscular blocking agent Pancuronium. It acts as a competitive antagonist of the nicotinic acetylcholine receptor.
T32066	Hexafluronium Bromide Mylaxen,Hexafluorenium bromide,Milaxen,Hexafluorenium dibromide,Esafluronio bromuro
	Hexafluronium bromide is a neuromuscular blocker and nicotinic acetylcholine receptor antagonist used in anesthesiology to prolong and enhance the skeletal muscle relaxation of succinylcholine during surgery.
T69024	Homidium Cl
	Homidium Chloride is the chloride salt of ethidium (a fluorochrome), Ethidium Chloride intercalates within double-stranded nucleic acids, particularly DNA. In molecular biology, the bromide salt of ethidium is used to detect and visualize DNA after electrophoresis or in cytochemical preparations. In veterinary pharmacology, it is used as a trypanosomicide. Ethidium bromide and chloride are toxic substances and potent noncompetitive antagonists of the nicotinic acetylcholine receptor.
T25912	Oxypyrronium bromide L.D. 3055,Immetropan,LD 3055,LD3055,LD-3055
	Oxypyrronium bromide 一种含有季铵的抗胆碱能和解痉剂。在动物模型中，它抑制胃运动、迷走神经刺激或乙酰胆碱静脉注射引起的低血压；鼓索神经刺激引起的流涎和节前颈交感神经刺激引起收缩。
T69378	Homidium Free Base
	Homidium Free Base is a trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.
TMIH-0163	Clidinium Bromide-d5
	Clidinium Bromide-d5 是 Clidinium Bromide 的氘代化合物。Clidinium Bromide 的 CAS 号为 3485-62-9。Clidinium bromide 是季胺抗毒蕈碱剂，可通过减少胃酸和减慢肠道速度，缓解痉挛和腹部疼痛的症状。
T60332	Methacholine bromide
	Methacholine (Acetyl-β-methylcholine) bromide 是一种有效的muscarinic-3 (M3)激动剂。Methacholine bromide 直接作用于平滑肌上的乙酰胆碱受体，导致支气管收缩和气道变窄。Methacholine bromide 对识别支气管高反应性 (BHR) 显示出高灵敏度，BHR 是哮喘的重要特征。Methacholine bromide 可用于测量气道高反应性 (AHR)，作为评估具有哮喘样症状和正常静息呼气流速的个体的诊断辅助[2]。
T37702	Pancuronium (bromide hydrate)
	Pancuronium is an aminosteroid antagonist of muscle-type nicotinic acetylcholine receptors (nAChRs) with an IC50value of 14.8 nM using patch clamp electrophysiology in BOSC23 cells expressing mouse nAChRs.1It acts as a non-depolarizing neuromuscular blocking agent.2Pancuronium enhances anesthesia induced by isoflurane , reducing immobilization with an ED50value of 1.62 μg/kg.3 1.Liu, M., and Dilger, J.P.Site selectivity of competitive antagonists for the mouse adult muscle nicotinic acetylcholin...

化合物

Acetylcholine bromide

Cat.No: T20344

Target: Others

Atropine methyl bromide

Cat.No: T14345

Synonym: 甲溴阿托品,Methylatropine bromide

Target: AChR

prifinium bromide

Cat.No: T9420

Target: Others

Cat.No: T2387

Synonym: Gastrodyn,Glycopyrronium bromide,Robinul,Glycopyrrolate bromide,格隆溴铵

Target: AChR

Umeclidinium bromide

Cat.No: T4997

Synonym: 芜地溴铵,GSK573719A

Target: AChR

Methylbenactyzium Bromide

Cat.No: T6744

Synonym: Noinarin,Paragone,Methylbenactyzine Bromide,溴甲贝那替秦,Semulgin,Gastrimade

Target: AChR

Otilonium bromide

Cat.No: T1474

Synonym: Octylonium bromide,奥替溴铵,SP63

Target: Calcium Channel, AChR

Ipratropium bromide monohydrate

Cat.No: T0098

Synonym: Ipratropium bromide hydrate,溴化异丙托品单水合物

Target: AChR

Pancuronium dibromide

Cat.No: T0166

Synonym: Pancuronium bromide,Pavulon,泮库溴铵

Target: AChR

Tiotropium bromide

Cat.No: T1179

Synonym: Tiopropium,噻托溴铵,BA679 BR

Target: AChR

Decamethonium bromide

Cat.No: T0818

Synonym: 十烃溴铵,Decacuran,溴化十烃季胺,Syncurine

Target: AChR, AChE

Sofpironium bromide

Cat.No: T28827

Synonym: BBI4000,BBI 4000,BBI-4000

Target: Others, AChR

Clidinium bromide

Cat.No: T0786

Synonym: 克利溴铵,Ro 2-3773

Target: AChR

Propantheline bromide

Cat.No: T1006

Synonym: Neopepulsan,溴丙胺太林,Pro-Banthine,Neometantyl

Target: AChR

Vecuronium bromide

Cat.No: T1594

Synonym: ORG NC 45,维库溴铵

Target: AChR

Hexamethonium Bromide

Cat.No: T0287

Synonym: Gangliostat,溴化六甲铵,Simpatoblock,六甲溴铵,Hexamethonium Dibromide

Target: Apoptosis, Dopamine Receptor, AChR

Ipratropium Bromide

Cat.No: T6547

Synonym: Sch 1000,异丙托溴铵,Itrop,Atrovent

Target: AChR

Aclidinium bromide

Cat.No: T2555

Synonym: LAS 34273,LAS-W 330,阿地溴铵

Target: AChR

Mepenzolate Bromide

Cat.No: T0794

Synonym: Colibantil,Cantil,溴美喷酯,Cantilaque

Target: AChR

Methscopolamine

Cat.No: T0253

Synonym: Methscopolamine bromide,甲溴东莨菪碱,Hyoscine methyl bromide,(-)-Scopolamine methyl bromide

Target: AChR

Ethidium bromide

Cat.No: T1220

Synonym: EtBr,Homidium bromide,EB,溴化乙啶

Target: AChR

Rapacuronium bromide

Cat.No: T12690

Synonym: Org 9487

Target: Others

Ambutonium bromide

Cat.No: T14206

Synonym: BL700

Target: Others

Fazadinium bromide

Cat.No: T24057

Flutropium Bromide

Cat.No: T19640

Synonym: Ba598,Ba 598,Flubron,Ba-598

Dacuronium bromide

Cat.No: T23961

Synonym: NB 68,ORG 6368,NB68,Dacuronii bromidum

Hexafluronium Bromide

Cat.No: T32066

Synonym: Mylaxen,Hexafluorenium bromide,Milaxen,Hexafluorenium dibromide,Esafluronio bromuro

Cat.No: T69024

Oxypyrronium bromide

Cat.No: T25912

Synonym: L.D. 3055,Immetropan,LD 3055,LD3055,LD-3055

Homidium Free Base

Cat.No: T69378

Clidinium Bromide-d5

Cat.No: TMIH-0163

Methacholine bromide

Cat.No: T60332

Pancuronium (bromide hydrate)

Cat.No: T37702

Cat. No.	Product Name	Target	Signaling Pathways
T2198	Arecoline hydrobromide Arecoline HBr,氢溴酸槟榔碱,Arecoline bromide	AChR	Neuroscience
	Arecoline hydrobromide (Arecoline HBr) 是从槟榔中得到的一种生物碱，具有刺激、警觉、抗焦虑和抗寄生虫作用。它是烟碱和毒蕈碱乙酰胆碱受体的部分激动剂，可诱导氧化应激。

天然产物

Arecoline hydrobromide

Cat.No: T2198

Synonym: Arecoline HBr,氢溴酸槟榔碱,Arecoline bromide

Target: AChR

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