Cat. No. | Product Name | Target | Signaling Pathways |
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T24956 |
(18F)LBT 999
(18F)LBT999,LBT999 18F,LBT 999 18F,LBT-999 18F,(18F)LBT-999 |
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(18F)LBT 999 is a positron emission tomography (PET) tracer, used for the quantification of the dopamine transporter (DAT) in the healthy rat brain. | |||
T33493 |
Mppf F-18
J1.050.795B,P-18FMPPF,(18F) Mppf,(18F)Mppf,(18F)-Mppf |
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Mppf F-18, which has been used as a radioactive ligand for positron emission tomography, is a compound that binds to the serotonin-1A receptor. | |||
T31086 |
CPFPX
[18F]CPFPX |
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CPFPX is a highly selective radioactive ligand for the A1 adenosine receptor (A1AR). | |||
T31823 |
Fluorodopa F 18
Fluorodopa (18F),6-(18F)Fluoro-L-DOPA,F-DOPA,L-6-(18F)Fluoro-DOPA,6-(18F)Fluorodopamine |
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Fluorodopa F 18 can be used as radioactive agent. | |||
T31758 |
Fecnt F-18
J2.661.350G,18F-Fecnt,(18F)-Fecnt |
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[F-18] FECNT has been widely used to calculate dopamine transporter (DAT) occupancy rates in the brains of non-human primates and can distinguish DAT density differences between Parkinson's disease and healthy human controls. | |||
T31803 |
Florilglutamic acid (18F)
Florilglutamic acid f-18,Florilglutamic acid ((Sup 18)f),Florilglutamic acid (18-f) |
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Florilglutamic acid (18F) is a bioactive chemical. | |||
T24406 |
L-FMAC F-18
L-(18F)-FMAC |
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L-FMAC F-18 has potential diagnostic activity during positron emission tomography (PET) imaging. After phosphorylation by DCK, the 18F moiety can be visualized by PET imaging. | |||
T31787 |
Fet F-18
Fet F18,18F-Fluoroethyltyrosine,18F-FET |
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Fet F-18 is an amino acid analog radiolabeled with fluorine F-18, a positron-emitting isotope, can be used as a tracer in positron emission tomography (PET). | |||
T25294 |
DCFBC F-18
18F-DCFBC |
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DCFBC F-18 is a radioconjugate containing a low molecular weight tracer, DCFBC, specific for prostate-specific membrane antigen (PSMA) and labeled with the positron-emitting isotope F 18 with potential prostate tumor imaging upon positron emission tomogra | |||
T33277 |
Mefway F-18
18F-Mefway |
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Mefway F-18 is a PET radioligand specific to serotonin-1A receptors. | |||
T25295 |
Dcfpyl F-18
18F-DCFPyL |
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Dcfpyl F-18 is used as a PET imaging agent for prostate-specific membrane antigen (PSMA). | |||
T74180 |
[18F]-Labeled L-dopa precursor
|
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[18F]-Labeled L-dopa precursor 是用于合成 18F-labeled L-dopa 的前体。 | |||
T31040 |
CP-18 F-18
CP18 F-18,CP 18 F-18,(18F)-CP18 |
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CP-18 F-18 is a DEVD (the caspase 3 substrate recognition motif) that is an imaging tracer for caspase-3 activity in apoptotic cells. | |||
T70597 |
G-749 hydrochloride
|
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G-749 hydrochloride is a novel FLT3 inhibitor that showed potent and sustained inhibition of the FLT3 wild type and mutants including FLT3-ITD, FLT3-D835Y, FLT3-ITD/N676D, and FLT3-ITD/F691L in cellular assays. | |||
T4683 |
Alovudine
3'-Deoxy-3'-fluorothymidine,3'-脱氧-3-氟胸苷 |
Antiviral | Immunology/Inflammation |
Alovudine (3'-Deoxy-3'-fluorothymidine) 是一种 DNA 合成的标志物。与18F-Fluorodeoxyglucose (FDG) 相比,它不易受炎症变化的影响,在胰腺癌中,它是更好的生物标志物。 | |||
T3187 |
Fluoroclebopride
|
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Fluoroclebopride 能够与多巴胺受体可逆结合,用18F 标记后可用作 PET 探针,能够标记多种猴子模型中的 D2/D3 多巴胺受体。 | |||
T8637 |
DMNB
6-Nitroveratraldehyde,6-硝基藜芦醛 |
DNA-PK | DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling |
DMNB (6-Nitroveratraldehyde) 可用于合成no-carrier-added 6-[18F]fluoro-L-DOPA (6-FDOPA)。它可用于研究多巴胺能系统的PET。 | |||
T15162 |
DPA-714
|
Others | Others |
DPA-714 是高亲和力的移位蛋白配体 (Ki=7 nM),它结构中有一个氟原子,能够被氟 -18 进行标记,并可通过正电子发射断层成像进行活体成像。它可在各种神经炎症模型及脑肿瘤模型中成功评估炎症的特异性成像。 | |||
T31410 |
D-Fluoromethyltyrosine F-18
BAY 86 9596,BAY 869596,BAY 86-9596,J2.566.882K,BAY-86-9596 F-18 |
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Fluoroethyl-l-tyrosine (18F) or 18F-FET is a neuro-oncology PET tracer. | |||
T39119 |
Fluoroethylnormemantine hydrochloride
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Fluoroethylnormemantine hydrochloride, a Memantine derivative, functions as an antagonist for the N-methyl-D-aspartate (NMDA) receptor. It can also serve as a positron emission tomography (PET) tracer, specifically as [18F]-Fluoroethylnormemantine hydrochloride. Notably, this compound displays a range of effects, including anti-amnesic, neuroprotective, antidepressant-like, and fear-attenuating properties. | |||
T33448 |
ML 10
ML-10,ML10 |
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ML 10 is is a [18F] positron emission tomography (PET) radiotracer that accumulates in cells presenting apoptosis-specific membrane alterations. [18F]ML-10 allows for the detection of apoptotic cells located in atherosclerotic plaques. | |||
T74143 |
AZD4694 Precursor
|
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AZD4694 Precursor (AZ13040214) 为[18F] AZD4694合成前体,专用于[18F] AZD4694的合成。该前体作为淀粉样蛋白-β成像配体,展现对淀粉样蛋白-β斑块的高亲和性。 | |||
T30216 |
AV-105
AV105,AV 105 |
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Av-105 is the precursor of florbetapir (18F). It is a radiopharmaceutical compound scanned by pet, which can be used as a diagnostic tool for Alzheimer's disease. | |||
T27840 |
LMI-1195
LMI 1195 |
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LMI-1195 is a 18F-labeled ligand for the norepinephrine transporter. LMI-1195 is used for mapping cardiac nerve terminals in vivo using positron emission tomography (PET). | |||
T19550 |
ROS tracer precursor
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Others | Others |
ROS tracer precursor, the synthesis precursor for [18F]ROStrace, serves in the production of ROStrace. This compound is instrumental in disease diagnosis. | |||
T79577 |
CB2 PET Radioligand 1
|
Cannabinoid Receptor | GPCR/G Protein |
CB2PET Radioligand 1 (compound [18F]9) 作为hCB2靶向的PET Radioligand (Ki=7.7 nM),采用Cu介导的18F-氟化方法制备,并在小鼠神经炎症模型中展现了高脑摄取率。 | |||
T18488 |
NH2-MPAA-NODA
|
Others | Others |
NH2-MPAA-NODA, a nitroveratryl-based photocleavable linker featuring a NODA motif and a methyl phenyl acetic acid (MPAA) backbone, serves as a radiolabel when labeled with 18F-fluoride. | |||
T41082 |
Flobetapir
AV-45,Flobetapir |
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Flobetapir (AV-45) is a well-tolerated imaging compound used in PET scanning. It is synthesized to create Florbetapir (18F), which is a radiopharmaceutical compound containing fluorine-18 radionuclide. | |||
T38855 | Melanin probe-1 | ||
Melanin probe-1, an 18F-picolinamide-based PET probe, is utilized for PET imaging of malignant melanoma. It demonstrates remarkable tumor targeting efficacy, superior tumor imaging contrasts, favorable biodistribution profiles, and robust in vivo stability. | |||
T79199 |
F-CRI1
|
STING | Immunology/Inflammation |
F-CRI1为高效STING激动剂,Kd值达40.62 nM。该化合物通过18F标记成为放射性探针,适用于肿瘤微环境中STING可视化的研究。 | |||
T62783 |
RIPK2-IN-1
|
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RIPK2-IN-1 (compound 18f) 是一种 RIPK2 的有效抑制剂 (IC50: 51 nM),也能够抑制 ALK2 (IC50: 5 nM)。RIPK2-IN-1 在细胞试验中对 RIPK2/NOD2 的 IC50 为 390 nM。 | |||
T39120 |
Fluoroethylnormemantine
|
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Fluoroethylnormemantine, a derivative of Memantine, acts as an N-methyl-D-aspartate (NMDA) receptor antagonist. It can function as a positron emission tomography (PET) tracer, known as [18F]-fluoroethylnormemantine. This compound displays anti-amnesic, neuroprotective, antidepressant-like, and fear-attenuating properties. | |||
T78927 |
PSMA-IN-3
|
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PSMA-IN-3(compound 17)是一种高亲和力的新型PSMA抑制剂,IC50为13 nM。该化合物可作为开发18F标记的放射性配体的基础,用于前列腺癌PSMA的PET成像。 | |||
T75022 | JZP-MA-11 | ||
JZP-MA-11是一种用于正电子发射断层扫描(PET)的配体,专一性靶向内源性大麻素α/β-水解酶结构域6(ABHD6)酶,并具有126 nM的IC50值,表明其对ABHD6有选择性抑制作用。JZP-MA-11能有效穿过血脑屏障(BBB)。[18F]JZP-MA-11展现出在靶向小鼠及非人灵长类(NHP)大脑ABHD6方面的临床前评估潜力。 | |||
T79716 |
c-ABL-IN-5
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Bcr-Abl | Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
c-ABL-IN-5是一种选择性c-Abl抑制剂,具有神经保护功能。该化合物显示出血脑屏障渗透性、代谢稳定性和优良的药物动力学特性。经[18F]标记的c-ABL-IN-5(化合物[18F]3)可用作PET示踪剂,以评估疾病改善的功效。此外,c-ABL-IN-5适用于帕金森病(PD)等神经退行性疾病的研究。 | |||
T61087 |
THK-5105
|
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THK-5105为芳基喹啉衍生物,具备与tau原纤维高度结合的亲和力。它对tau蛋白聚集体及含tau的阿尔茨海默病(AD)脑匀浆显示出显著的结合能力。18F-THK-5105展现出作为tau成像PET探针的潜能。 | |||
T74786 | BIBD-124 | ||
BIBD-124 通过与淀粉样蛋白 (Aβ) 斑块结合,展现出优异的亲和力,其 IC50 值达到了 9.51 nM。作为一种放射性示踪剂,[18F]BIBD-124 能够针对 Aβ 斑块进行高效的标记。 | |||
T64640 | Melanin probe-2 | ||
Melanoma is a lethal skin cancer. The early detection of melanoma using positron emission tomography (PET) probes is critical for improving the survival of melanoma patients. Melanin probe-2 is a non-radioactive bromo-picolinamide precursor that has been used for the synthesis of18F-picolinamides based PET probe (melanin probe-1). The tumor-targeting efficacy and imaging property of three melanin probes were evaluated in B16F10 tumor-bearing mice.18F-1 and18F-3 had much lower tumor uptake compar... | |||
T60543 |
THK-523
|
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THK-523 在体内外都显示出对tau 的选择性和高亲和力。18F-THK-523 是一种有效的 tau 成像放射性示踪剂,它是用于研究阿尔茨海默病的有效体内 tau 成像配体。 | |||
T74974 | SQ-3 | ||
SQ-3为一种喹啉类似物,对α-syn聚合体(Ki=39.3 nM)显示中等选择性,其选择性高于对β-淀粉样蛋白(Aβ)聚合体(Ki=230 nM)。[18F]SQ3展现出作为α-syn成像探针的先导化合物的基本属性。 |