3
2
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T23228 |
(R,S)-Anatabine (tartrate) (2743-90-0 free base)
(R,S)-Anatabine (tartrate) |
Others | Others |
Anatabine is a minor tobacco alkaloid with a chemical structural similarity to nicotine. Anatabine is produced in plants of the Solanacea family including tobacco, green tomatoes, peppers, and eggplants. Anatabine is an Aβ inhibitor. (R,S)-Anatabine (tart | |||
T12636 |
(R)-(+)-Anatabine
|
Others | Others |
(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR. | |||
T10318 |
Anatabine dicitrate
|
NF-κB | NF-κB |
Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier. It is a potent α4β2 nAChR agonist and inhibits NF-κB activation lower amyloid-β (Aβ) production by preventing the β-cleavage of the amyloid precursor protein. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13857 |
(R,S)-Anatabine
|
Others | Others |
(R,S)-Anatabine 是一种茄科植物中发现的次要烟草生物碱,可用于烟草使用中特定标记物的检测。 | |||
TN3410 |
Anatabine
|
Beta Amyloid; IL Receptor; TNF; NF-κB; BACE; COX; STAT | Apoptosis; Immunology/Inflammation; JAK/STAT signaling; Neuroscience; NF-κB; Stem Cells |
Anatabine shows anti-inflammatory activity in vitro and in vivo, which is mediated in part via an inhibition of STAT3 phosphorylation.Anatabine has anti-Alzheimer's disease effects, it inhibits BACE-1 transcription and reduces BACE-1 protein levels in hum |