肿瘤坏死因子家族

肿瘤坏死因子 (Tumor Necrosis Factor family, TNFs) 超家族是 II 型跨膜蛋白的蛋白质超家族，含有 TNF 同源结构域并形成三聚体。TNFs的成员可以通过细胞外蛋白水解裂解从细胞膜中释放出来，并作为细胞因子发挥作用。这些蛋白质主要由免疫细胞表达，它们调节多种细胞功能，包括免疫反应和炎症，以及增殖、分化、凋亡和胚胎发生。TNFs包含 19 个成员，与 TNF 受体超家族的 29 个成员结合。肿瘤坏死因子受体超家族（Tumor necrosis factor receptor superfamily, TNFRSF）是细胞因子受体的蛋白质超家族，其特征在于能够通过富含细胞外半胱氨酸的结构域结合TNF。TNFs的 PROSITE 模式位于蛋白质中央部分的 β 折叠中，该折叠在所有成员中都是保守的。

Cat. No.	Product Name / Synonyms	Species	Expression System
TMPY-04146	TNF alpha Protein, Human, Recombinant (hFc) TNF alpha Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPY-04146	TNF alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.8 kDa and the accession num...
TMPY-04832	OX40L/TNFSF4 Protein, Human, Recombinant (hFc) OX40L/TNFSF4 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPY-04832	OX40L/TNFSF4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.6 kDa.
TMPY-02153	TNF beta Protein, Human, Recombinant TNF beta Protein, Human, Recombinant	Human	E. coli
TMPY-02153	Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs ...
TMPY-01920	BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)	Human	HEK293 Cells
TMPY-01920	BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q...
TMPY-05365	BAFF/TNFSF13B Protein, Human, Recombinant (Avi & Fc), Biotinylated BAFF/TNFSF13B Protein, Human, Recombinant (Avi & Fc), Biotinylated	Human	HEK293 Cells
TMPY-05365	BAFF/TNFSF13B Protein, Human, Recombinant (Avi & Fc), Biotinylated is expressed in HEK293 mammalian cells with AVI and Fc tag. The predicted molecular weight is ...
TMPY-03956	Fas Ligand Protein, Human, Recombinant (His) Fas Ligand Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
TMPY-03956	Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is...
TMPY-00033	4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc) 4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPY-00033	4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.9 kDa and the acc...
TMPY-03364	RANKL/TNFSF11/CD254 Protein, Human, Recombinant RANKL/TNFSF11/CD254 Protein, Human, Recombinant	Human	HEK293 Cells
TMPY-03364	RANKL/TNFSF11/CD254 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.5 kDa and the accession number is AA...
TMPJ-00137	APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His) APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
TMPJ-00137	APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa...
TMPJ-00139	4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His) 4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His)	Human	E. coli
TMPJ-00139	4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 16-20 KDa and...
TMPJ-00603	TL1A/TNFSF15 Protein, Mouse, Recombinant TL1A/TNFSF15 Protein, Mouse, Recombinant	Mouse	E. coli
TMPJ-00603	Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-sp...
TMPJ-00607	RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
TMPJ-00607	RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 30-35 KDa and th...
TMPJ-00662	RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli) RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)	Human	E. coli
TMPJ-00662	CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune s...
TMPJ-00779	TNF alpha Protein, Rabbit, Recombinant TNF alpha Protein, Rabbit, Recombinant	Rabbit	E. coli
TMPJ-00779	Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TN...
TMPJ-01391	BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc) BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)	Mouse	HEK293 Cells
TMPJ-01391	BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with N-mFc tag. The predicted molecular weight is 45-60 KDa and the access...
TMPY-01294	TNF alpha Protein, Mouse, Recombinant TNF alpha Protein, Mouse, Recombinant	Mouse	E. coli
TMPY-01294	TNF alpha Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.39 kDa and the accession number is P06804.
TMPY-02202	TNF alpha Protein, Rat, Recombinant TNF alpha Protein, Rat, Recombinant	Rat	E. coli
TMPY-02202	TNF alpha Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession number is P16599.