肿瘤坏死因子家族

肿瘤坏死因子 (Tumor Necrosis Factor family, TNFs) 超家族是 II 型跨膜蛋白的蛋白质超家族，含有 TNF 同源结构域并形成三聚体。TNFs的成员可以通过细胞外蛋白水解裂解从细胞膜中释放出来，并作为细胞因子发挥作用。这些蛋白质主要由免疫细胞表达，它们调节多种细胞功能，包括免疫反应和炎症，以及增殖、分化、凋亡和胚胎发生。TNFs包含 19 个成员，与 TNF 受体超家族的 29 个成员结合。肿瘤坏死因子受体超家族（Tumor necrosis factor receptor superfamily, TNFRSF）是细胞因子受体的蛋白质超家族，其特征在于能够通过富含细胞外半胱氨酸的结构域结合TNF。TNFs的 PROSITE 模式位于蛋白质中央部分的 β 折叠中，该折叠在所有成员中都是保守的。

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Expression System：

Tag：

Cat. No.	Product Name / Synonyms	Species	Expression System
TMPK-00079	CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His) CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His)	Human	HEK293 Cells
TMPK-00079	CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a...
TMPK-00080	CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
TMPK-00080	CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a...
TMPK-00119	TNF alpha Protein, Cynomolgus, Recombinant (His) TNF alpha Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
TMPK-00119	TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 18.35 kDa and the acces...
TMPK-00120	TNF alpha Protein, Human, Recombinant (His & Avi) TNF alpha Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
TMPK-00120	TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 20.3 kDa and the a...
TMPK-00121	TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
TMPK-00121	TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 20.3...
TMPK-00122	CD30 Ligand/TNFSF8 Protein, Human, Recombinant (His) CD30 Ligand/TNFSF8 Protein, Human, Recombinant (His)	Human	HEK293 Cells
TMPK-00122	CD30 ligand (CD30L)/TNFSF8 is a type II membrane protein belonging to the TNF superfamily. CD30L is expressed on the cell surface of activated T cells, B cells, ...
TMPK-00130	LIGHT/TNFSF14 Trimer Protein, Human, Recombinant (His & Flag) LIGHT/TNFSF14 Trimer Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
TMPK-00130	LIGHT, also known as tumor necrosis factor superfamily member 14 (TNFSF14), is a secreted protein of the TNF superfamily. It is recognized by herpesvirus entry m...
TMPK-00140	APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Avi & Flag), Biotinylated APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Avi & Flag), Biotinylated	Human	HEK293 Cells
TMPK-00140	The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close r...
TMPK-00141	APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Flag) APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
TMPK-00141	The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close r...
TMPK-00142	APRIL/TNFSF13 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated APRIL/TNFSF13 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated	Human	HEK293 Cells
TMPK-00142	The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close r...
TMPK-00143	TL1A/TNFSF15 Trimer Protein, Human, Recombinant (His & Flag) TL1A/TNFSF15 Trimer Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
TMPK-00143	TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells,...
TMPK-00154	CD40 Ligand Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated CD40 Ligand Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated	Human	HEK293 Cells
TMPK-00154	CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It b...
TMPK-00171	TRAIL Trimer Protein, Human, Recombinant (His & Flag) TRAIL Trimer Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
TMPK-00171	Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can initiate the apoptosis pathway by binding to it...
TMPK-00174	BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Avi), Biotinylated BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
TMPK-00174	B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAF...
TMPK-00175	BAFF/TNFSF13B Protein, Human, Recombinant (monomeric hFc, Flag) BAFF/TNFSF13B Protein, Human, Recombinant (monomeric hFc, Flag)	Human	HEK293 Cells
TMPK-00175	B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAF...
TMPK-00176	BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag) BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
TMPK-00176	B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAF...
TMPK-00489	TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)	Cynomolgus,Rhesus	HEK293 Cells
TMPK-00489	TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells,...
TMPK-00510	BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi, Flag), Biotinylated BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi, Flag), Biotinylated	Cynomolgus	HEK293 Cells
TMPK-00510	B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAF...
TMPK-00511	BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi) BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi)	Cynomolgus	HEK293 Cells
TMPK-00511	B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAF...
TMPK-00583	TNF alpha Protein, Ferret, Recombinant (His) TNF alpha Protein, Ferret, Recombinant (His)	Ferret	E. coli
TMPK-00583	TNF alpha Protein, Ferret, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 18.88 kDa and the access...