肿瘤坏死因子家族

肿瘤坏死因子 (Tumor Necrosis Factor family, TNFs) 超家族是 II 型跨膜蛋白的蛋白质超家族，含有 TNF 同源结构域并形成三聚体。TNFs的成员可以通过细胞外蛋白水解裂解从细胞膜中释放出来，并作为细胞因子发挥作用。这些蛋白质主要由免疫细胞表达，它们调节多种细胞功能，包括免疫反应和炎症，以及增殖、分化、凋亡和胚胎发生。TNFs包含 19 个成员，与 TNF 受体超家族的 29 个成员结合。肿瘤坏死因子受体超家族（Tumor necrosis factor receptor superfamily, TNFRSF）是细胞因子受体的蛋白质超家族，其特征在于能够通过富含细胞外半胱氨酸的结构域结合TNF。TNFs的 PROSITE 模式位于蛋白质中央部分的 β 折叠中，该折叠在所有成员中都是保守的。

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Cat. No.	Product Name / Synonyms	Species	Expression System
TMPK-00591	RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His) RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His)	Mouse	HEK293 Cells
TMPK-00591	Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune s...
TMPK-00666	CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His) CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
TMPK-00666	CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a...
TMPK-00716	RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244) RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244)	Human	HEK293 Cells
TMPK-00716	Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune s...
TMPK-00717	RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag) RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
TMPK-00717	Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune s...
TMPK-00727	TNFSF12/TWEAK Protein, Human, Recombinant (hFc) TNFSF12/TWEAK Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPK-00727	Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a well known multifunctional cytokine extensively distributed in cell types and tissues. Accumula...
TMPK-00860	CD40 Ligand Protein, Mouse, Recombinant (monomeric hFc) CD40 Ligand Protein, Mouse, Recombinant (monomeric hFc)	Mouse	HEK293 Cells
TMPK-00860	CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It b...
TMPK-01011	TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi) TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi)	Mouse	HEK293 Cells
TMPK-01011	TNFSF15 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.40 kDa and the ac...
TMPK-01012	TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi), Biotinylated TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
TMPK-01012	TNFSF15 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.40 ...
TMPK-01013	TL1A/TNFSF15 Protein, Mouse, Recombinant (hFc) TL1A/TNFSF15 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
TMPK-01013	TNFSF15 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 48.8 kDa and the accession num...
TMPK-01064	GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc) GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
TMPK-01064	Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, pro...
TMPK-01163	APRIL/TNFSF13 Protein, Mouse, Recombinant (His & Flag) APRIL/TNFSF13 Protein, Mouse, Recombinant (His & Flag)	Mouse	HEK293 Cells
TMPK-01163	The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close r...
TMPK-01349	APRIL/TNFSF13 Trimer Protein, Cynomolgus, Recombinant (His & Avi, Flag) APRIL/TNFSF13 Trimer Protein, Cynomolgus, Recombinant (His & Avi, Flag)	Cynomolgus	HEK293 Cells
TMPK-01349	The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close r...
TMPJ-01472	RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His) RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His)	Mouse	HEK293 Cells
TMPJ-01472	RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 23-2...
TMPK-01398	CD40 Ligand Trimer Protein, Human, Recombinant (hFc) CD40 Ligand Trimer Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPK-01398	CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It b...
TMPY-00248	Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His) Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Baculovirus Insect Cells
TMPY-00248	LTB (Lymphotoxin Beta) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. Lymphotoxin beta is a type II membrane protein of the...
TMPY-00537	RANKL/TNFSF11/CD254 Protein, Cynomolgus, Recombinant (hFc) RANKL/TNFSF11/CD254 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
TMPY-00537	RANKL/TNFSF11/CD254 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.9 kDa and th...
TMPY-00584	TWEAK/TNFSF12 Protein, Mouse, Recombinant (hFc) TWEAK/TNFSF12 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
TMPY-00584	TWEAK/TNFSF12 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.4 kDa and the accession...
TMPY-00618	BAFF/TNFSF13B Protein, Canine, Recombinant (hFc) BAFF/TNFSF13B Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells
TMPY-00618	BAFF/TNFSF13B Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.5 kDa and the accessio...
TMPY-00959	4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (His) 4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
TMPY-00959	4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the acces...
TMPY-01239	BAFF/TNFSF13B Protein, Human, Recombinant (hFc) BAFF/TNFSF13B Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPY-01239	BAFF/TNFSF13B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.7 kDa and the accession...

RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His)