Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bruceine A (NSC-31616) 是一种从鸦胆子 (L.) 的干果中提取的天然类苦素化合物,有治疗犬巴贝斯虫病的潜力。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 338 | 现货 | ||
5 mg | ¥ 788 | 现货 | ||
10 mg | ¥ 1,150 | 现货 | ||
25 mg | ¥ 1,930 | 现货 | ||
50 mg | ¥ 2,880 | 现货 | ||
100 mg | ¥ 4,270 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 1,230 | 现货 |
产品描述 | Bruceine A (NSC-31616)(NSC-310616; Dihydrobrusatol) is a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.); are potential candidates for the treatment of canine babesiosis. |
体外活性 | Bruceine A inhibited the in vitro growth of Babesia gibsoni in canine erythrocytes at lower concentration compared with the standard antibabesial drug diminazene aceturate and killed the parasites within 24 hr at a concentration of 25 nM. |
体内活性 | Oral administration of bruceine A at a dosage of 6.4 mg/kg/day for 5 days resulted in no clinical findings in a dog with normal ranges of hematological and biochemical values in the blood. Three dogs were infected with B. gibsoni and two of them were treated with bruceine A at a dosage of 6.4 mg/kg/day for 6 days from day 5 post-infection. |
别名 | Dihydrobrusatol, 鸦胆子素 A, NSC31616 |
分子量 | 522.54 |
分子式 | C26H34O11 |
CAS No. | 25514-31-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 12 mg/mL (22.96 mM ), Heating is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 1.9137 mL | 9.5686 mL | 19.1373 mL | 47.8432 mL |
5 mM | 0.3827 mL | 1.9137 mL | 3.8275 mL | 9.5686 mL | |
10 mM | 0.1914 mL | 0.9569 mL | 1.9137 mL | 4.7843 mL | |
20 mM | 0.0957 mL | 0.4784 mL | 0.9569 mL | 2.3922 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Bruceine A 25514-31-2 Microbiology/Virology Antibiotic Parasite NSC 310616 NSC-310616 NSC 31616 inhibit Dihydrobrusatol Inhibitor 鸦胆子素 A NSC-31616 NSC31616 NSC310616 inhibitor