Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Benzyldodecyldimethylammonium chloride dihydrate 可以用作杀虫试剂,可以靶向耐药性细菌,如耐甲氧西林金黄色葡萄球菌、耐多药铜绿假单胞菌等,且具有浓度依赖性。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
500 mg | ¥ 413 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 455 | 现货 |
产品描述 | Benzyldodecyldimethylammonium chloride dihydrate can be used as an insecticide reagent. It can target drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, multidrug-resistant Pseudomonas aeruginosa, etc., in a concentration-dependent manner. |
靶点活性 | P. fluorescens:20 mg/L(MIC) |
体外活性 | Benzyldodecyldimethylammonium chloride dihydrate interacts strongly with cell surfaces in a concentration-dependent manner, and binds by ionic and hydrophobic interactions to microbial membrane surfaces, as manifested by phenomena such as membrane disruption and loss of membrane integrity with consequent leakage of essential intracellular constituents, which promote significant and irreversible changes in the cell structure[2]. Benzyldodecyldimethylammonium chloride dihydrate (0-40 mg/L; 0-24 hours) inhibits P. fluorescens with a MIC of 20 mg/L. At 5 mg/L, cells have the same growth behaviour as the control. At concentrations of 10 and 15 mg/L the growth profile is different from the control, and the cells start to grow only after 8 h of adaptation. At concentrations of ≥20 mg/L, BDMDAC inhibits cell growth[2]. |
体内活性 | Benzyldodecyldimethylammonium chloride dihydrate (1-10 μM; 2 hours) results in a dose-dependent changes in the percent population of dead rat thymocyte cells[1]. |
分子量 | 376.02 |
分子式 | C21H42ClNO2 |
CAS No. | 147228-80-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 99 mg/mL (263.28 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.6594 mL | 13.2972 mL | 26.5943 mL | 66.4858 mL |
5 mM | 0.5319 mL | 2.6594 mL | 5.3189 mL | 13.2972 mL | |
10 mM | 0.2659 mL | 1.3297 mL | 2.6594 mL | 6.6486 mL | |
20 mM | 0.133 mL | 0.6649 mL | 1.3297 mL | 3.3243 mL | |
50 mM | 0.0532 mL | 0.2659 mL | 0.5319 mL | 1.3297 mL | |
100 mM | 0.0266 mL | 0.133 mL | 0.2659 mL | 0.6649 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Benzyldodecyldimethylammonium Chloride Dihydrate 147228-80-6 Microbiology/Virology Antibacterial MRSA inhibit S. aureus thymocyte E. coli Inhibitor Disinfection,?QAC,?Biocide Benzyldodecyldimethylammonium Chloride Pseudomonas fluorescens MDR Bacterial antimicrobial inhibitor