Prostaglandin Receptor

Prostaglandin receptors or prostanoid receptors represent a sub-class of cell surface membrane receptors that are regarded as the primary receptors for one or more of the classical, naturally occurring prostanoids viz., prostaglandin D2, , PGE2, PGF2alpha, prostacyclin (PGI2), thromboxane A2 (TXA2), and PGH2.[1] They are named based on the prostanoid to which they preferentially bind and respond, e.g. the receptor responsive to PGI2 at lower concentrations than any other prostanoid is named the Prostacyclin receptor (IP). One exception to this rule is the receptor for thromboxane A2 (TP) which binds and responds to PGH2 and TXA2 equally well.

Cat. No.	Product Name	CAS No.	Purity
T14842	BW 245C 化合物 BW 245C	72814-32-5	98%
T14842	BW 245C 是一种选择性的前列腺素类DP受体(DP1)激动剂，是一种前列腺素类似物，对胶原蛋白的聚集反应有抑制作用，可用于研究中风等疾病。
TN1171	6-Dehydrogingerdione 1-脱氢-6-姜酮	76060-35-0	98%
TN1171	1-Dehydro-6-gingerdione is a 5-HT1A receptor partial agonist.
T8993	BGC201531 化合物BGC201531	1186532-61-5	98%
T8993	BGC201531 (AP-1531) 是一种 EP4 拮抗剂，用于治疗急性偏头痛。
TN2169	Saikogenin D 皂苷元 D	5573-16-0	98%
TN2169	Saikogenin D possesses a dual effect: an inhibition of A23187-induced PGE2 production without a direct inhibition of cyclooxygenase activity; and an elevation of...
TN5017	Sideritoflavone 化合物 TN5017	70360-12-2	98%
TN5017	Sideritoflavone has anti-inflammatory effect, it is a selective inhibitor of lipoxygenase activity in vitro.
TN5011	Shizukaol B 化合物 TN5011	142279-40-1	98%
TN5011	Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl...
T12100	MPGES1-IN-3 化合物 T12100	1469976-70-2	98%
T12100	mPGES1-IN-3 is a potent and selective inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) .
TN4062	Flavidin 化合物 TN4062	83924-98-5	98%
TN4062	Flavidin shows very good antioxidant capacity. Flavidin can enhance fluorescent imaging, allowing more sensitive and specific cell labeling in tissues, it should...
T37991	15-keto Prostaglandin F2α 化合物15-keto Prostaglandin F2α	35850-13-6	98%
T37991	15-keto Prostaglandin F2α 是 Prostaglandin F2α 的代谢物，可降低兔眼压。
T14139	Aganepag 化合物 T14139	910562-18-4	98%
T14139	Aganepag, a potent Prostanoid EP2 receptor agonist, exhibits remarkable selectivity with an EC50 of 0.19 nM, demonstrating no activity at the EP4 receptor. Its a...
TN4748	Penduletin 化合物 TN4748	569-80-2	98%
TN4748	Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Pendule...
T17092	Tiaprost 化合物 T17092	71116-82-0	98%
T17092	Tiaprost is a analog of prostaglandin F2α .
T37326	Prostaglandin F2α 1,11-lactone 化合物T37326	62410-84-8	98%
T37326	Prostaglandin F2α 1,11-lactone (PGF2α 1,11-lactone) 是前列腺素 F2α 的脂溶性前药，可用于治疗青光眼的研究。 Prostaglandin F2α 1,11-lactone 作为抗生育剂具有活性，可大大降低血管活性。
TN1378	α-Viniferin α-葡萄素	62218-13-7	98%
TN1378	α-Viniferin 也称为2-芳基苯并呋喃类黄酮，是前列腺素H2合成酶抑制剂。具有抗阿尔茨海默病、抗结核、抗肿瘤、抗炎、抗糖尿病等多种药理活性
T15642	KAG-308 化合物 T15642	1215192-68-9	98%
T15642	KAG-308 is an effective selective and orally active agonist of the EP4 receptor (Ki: 2.57 nM and EC50: 17 nM for human EP4 receptor), more selective over EP1, EP...
TN1009	Epimagnolin B 表木兰脂素 B	1134188-26-3	98%
TN1009	Epimagnolin B 是一种双环氧木质素，分离自木兰中。它能够抑制 LPS 激活的小胶质细胞中 NO 的产生。它具有抗过敏以及抗炎作用。
TN4463	Lupeolic acid 化合物 TN4463	87355-32-6	98%
TN4463	Lupeolic acid has anti-inflammatory activity.
TN4064	Flavoglaucin 化合物 TN4064	523-73-9	98%
TN4064	Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannab...
T14146	AGN 210676 化合物 T14146	910562-15-1	98%
T14146	AGN 210676 is a selective agonist of prostaglandin EP2(EC50 : 5 nM).
TN4303	Isokaempferide 化合物 TN4303	1592-70-7	98%
TN4303	Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by red...