Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T4480 | Vardenafil dihydrochloride
二盐酸伐地那非
|
224789-15-5 | 99.77% |
|
Vardenafil dihydrochloride (Levitra) 是一种新型 PDE 抑制剂,对 PDE5 和 PDE1 的 IC50 分别为 0.7 和 180 nM。 | ||||
TN2217 | Sophoflavescenol
槐苦参醇
|
216450-65-6 | 99.65% |
|
Sophoflavescenol 是异戊烯基黄酮类化合物,能够抑制PDE5的活性,IC50=0.013 μM。它也抑制 RLAR,HRAR,BACE1,AChE 和 BChE,IC50值分别为 0.30 µM,0.17 µM,10.98 µM,8.37 µM 和 8.21 µM。 | ||||
T60608 | FPFT-2216
化合物FPFT-2216
|
2367619-87-0 | 99.35% |
|
FPFT-2216 是一种分子胶,可降解 IKZF6、IKZF1、DE1D 和 CK3α。FPFT-2216 具有潜在的抗肿瘤活性,可用于研究免疫系统疾病。 | ||||
T19706 | Ro 20-1724
化合物Ro20-1724
|
29925-17-5 | 98.82% |
|
Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) 是 cAMP 特异性磷酸二酯酶抑制剂 b>(PDE4/PDE IV),其 Ki=1930 nM,具有神经保护作用。 | ||||
T22491 | PDE7-IN-2
化合物 PDE7-IN-2
|
107522-19-0 | 98% |
|
PDE7-IN-2 是磷酸二酯酶 7 (IC50 = 2.1 µM) 的抑制剂,可用于帕金森病研究。 | ||||
T10994 | Deltasonamide 2
化合物 T10994
|
2088485-34-9 | 98% |
|
Deltasonamide 2 is a competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM. | ||||
T12394 | PDE5-IN-2
化合物 T12394
|
2244517-61-9 | 98% |
|
PDE5-IN-2 is a potent, highly selective, and orally active inhibitor of PDE5(IC50 of 0.31 nM) | ||||
T16484 | PF-05180999
化合物 T16484
|
1394033-54-5 | 98% |
|
PF-05180999 is an inhibitor of phosphodiesterase 2A (IC50: 1.6 nM). | ||||
TN2095 | Pomiferin
橙桑黄酮
|
572-03-2 | 98% |
|
Pomiferin is a natural product inhibitor of carbonic anhydrase I and II isoenzymes. It has anticancer, antibacterial and antidiabetic properties. Pomiferin has a... | ||||
T16434 | PAT-048
化合物 T16434
|
1359983-15-5 | 98% |
|
PAT-048 is an effective and selective autotaxin inhibitor. PAT-048 reduces dermal fibrosis in vivo. PAT-048 also inhibits IL-6 mRNA expression but displays no ef... | ||||
TN2974 | 3-O-Methylquercetin tetraacetate
化合物 TN2974
|
1486-69-7 | 98% |
|
Quercetin 3-O-methyl ether is a potent phosphodiesterase (PDE)3/4 inhibitor, it has potential for treating asthma against ovalbumin-induced airway hyperresponsiv... | ||||
T10994L | Deltasonamide 2 hydrochloride
化合物 T10994L
|
T10994L | 98% |
|
Deltasonamide 2 hydrochloride is a competitive high-affinity PDEδ inhibitor with a Kd of approximately 385 pM. | ||||
TN4317 | Isopedicin
化合物 TN4317
|
4431-42-9 | 98% |
|
Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation of cellular cAMP and activation of PKA thr... | ||||
T14962 | CI-1044
化合物 T14962
|
197894-84-1 | 98% |
|
CI-1044 is an inhibitor of PDE4 (IC50s: 0.29, 0.08, 0.56, 0.09 μM for PDE4A5, PDE4B2, PDE4C2 and PDE4D3). | ||||
TN4397 | Kuraridine
次苦参素
|
34981-25-4 | 98% |
|
Kuraridine is measured against cGMP PDE5 to identify potent cGMP specific phosphodiesterase type 5 inhibitory constituents. | ||||
T11483 | GSK256066 Trifluoroacetate
化合物 T11483
|
1415560-64-3 | 98% |
|
GSK 256066 Trifluoroacetate is a selective and high-affinity phosphodiesterase 4 (PDE) inhibitor (IC50: 3.2 pM for PDE4B). It can be used for the treatment of ch... | ||||
T11206 | Ent-Tadalafil
化合物 T11206
|
629652-72-8 | 98% |
|
ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS). | ||||
T16482 | PF-05085727
化合物 T16482
|
1415637-72-7 | 98% |
|
PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11. PF-05085727 is an effective, selective and brain penetrant inhibitor of cGMP-dependent ... | ||||
T10418 | Autotaxin modulator 1
化合物 T10418
|
1548743-69-6 | 98% |
|
Autotaxin modulator 1 is a new modulator of Autotaxin. | ||||
TN4665 | Norbraylin
化合物 TN4665
|
60796-64-7 | 98% |
|
Norbraylin is a natural product from Toddalia asiatica. |