Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T16390 | Omtriptolide
昂曲托来
|
195883-06-8 | 98% |
|
Omtriptolide, triptolide purified from the Chinese herb, is a water-soluble derivative prodrug. | ||||
TN5011 | Shizukaol B
化合物 TN5011
|
142279-40-1 | 98% |
|
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl... | ||||
TN1889 | Lupalbigenin
化合物Lupalbigenin
|
76754-24-0 | 98% |
|
Lupalbigenin sensitizes detachment-induced cell death in human lung cancer cell through down-regulation of pro-survival proteins. | ||||
TN4774 | Physalin A
化合物 TN4774
|
23027-91-0 | 98% |
|
Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate canc... | ||||
TN1062 | Peonidin chloride
氯化芍药素
|
134-01-0 | 98% |
|
Peonidin chloride has antioxidant activity. Peonidin has show potent inhibitory and apoptotic effects on cancer cells in vitro, notably metastatic human breast c... | ||||
TN3139 | 5α-Hydroxycostic acid
化合物 TN3139
|
132185-83-2 | 98% |
|
5alpha-Hydroxycostic acid possesses anti-angiogenic ability by interfering the VEGF- and Ang2-related pathways, and it may be a good drug candidate. | ||||
TN1751 | Hydroxycitric acid
2-羟基柠檬酸
|
6205-14-7 | 98% |
|
(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of action of HCA appears to be related to its ability to ac... | ||||
TN1775 | Isocryptotanshinone
异隐丹参酮
|
22550-15-8 | 98% |
|
Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 μM, PTP1B acts as a negative r... | ||||
T15377 | Ravoxertinib hydrochloride
化合物 T15377
|
2070009-58-2 | 98% |
|
Ravoxertinib hydrochloride is an orally bioavailable and selective inhibitor for ERK kinase activity (IC50: 6.1 nM and 3.1 nM for ERK1 and ERK2, respectively). | ||||
TMA1743 | Ergosterol peroxide
过氧麦角甾醇
|
2061-64-5 | 98% |
|
Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Fox... | ||||
TN2328 | Zeylenone
山椒子烯酮
|
193410-84-3 | 98% |
|
Zeylenone 是一种来自 Uvaria grandiflora的环己烯氧化物,具有抗肿瘤和抗癌细胞增殖活性,通过 PI3K/AKT/mTOR 和 MAPK/ERK 信号通路抑制宫颈癌细胞增殖,诱导细胞凋亡 (apoptosis)。 | ||||
T10299 | AMG PERK 44
化合物 T10299
|
1883548-84-2 | 98% |
|
AMG PERK 44 is an orally active and selective PERK inhibitor (IC50: 6 nM) and induces autophagy. It has 1000-fold and 160-fold selectivity over GCN2 (IC50: 7300 ... | ||||
T13679 | Enniatin B
恩镰孢菌素 B
|
917-13-5 | 98% |
|
Enniatins B decreases the activation of ERK (p44/p42). Enniatin B is a Fusarium mycotoxin. Enniatin B inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activ... | ||||
TN4683 | Nyasol
化合物 TN4683
|
96895-25-9 | 98% |
|
Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory ... | ||||
TN1211 | 2-Hydroxy-3-methylanthraquinone
化合物2-Hydroxy-3-methylanthraquinone
|
17241-40-6 | 98% |
|
2-Hydroxy-3-methylanthraquinone enhances apoptosis of U937 cells,in part,through activation of p-p38MAPK and downregulation of p-ERK1/2; triggers caspase-3 activ... | ||||
T11228 | ERK2 IN-1
化合物 T11228
|
1093061-47-2 | 98% |
|
ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM. | ||||
TN4166 | Griffipavixanthone
化合物 TN4166
|
219649-95-3 | 98% |
|
Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, it induces cell apoptosis through mito... | ||||
TN3711 | Corylifol C
化合物 TN3711
|
775351-91-2 | 98% |
|
Corylifol C and, to a lesser extent, xanthoangelol are potent protein kinase inhibitors (inhibitory concentration 50% values for epidermal growth factor receptor... | ||||
TN4179 | Haginin A
化合物 TN4179
|
74174-29-1 | 98% |
|
Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB activ... | ||||
TL0014 | Pinusolide
化合物 TL0014
|
31685-80-0 | 98% |
|
Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, a... |