Akt

Protein kinase B (PKB), also known as Akt, is a serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration.

Cat. No.	Product Name	CAS No.	Purity
TN3726	Cudraflavone B 化合物 TN3726	19275-49-1	98%
TN3726	Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mo...
TN4046	Excisanin A 化合物 TN4046	78536-37-5	98%
TN4046	ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a pote...
TN1728	Hellebrigenin 蟾蜍它里定	465-90-7	98%
TN1728	Hellebrigenin has anti-hepatoma activities, it induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. H...
TN3517	Bisacurone 化合物 TN3517	120681-81-4	98%
TN3517	Bisacurone has anti-oxidant, anti-inflammatory, and anti-metastatic activities, it may have a protective effect against ethanol-induced liver injury by suppressi...
T10275	AKT-IN-3 化合物 T10275	2374740-21-1	98%
T10275	AKT-IN-3 is a potent, orally active low hERG blocking Akt inhibitor (IC50: 1.4 nM, 1.2 nM, and 1.7 nM for Akt1, Akt2, and Akt3). AKT-IN-3 (compound E22) also exh...
TN1379	Alphitolic acid 化合物Alphitolic acid	19533-92-7	98%
TN1379	Alphitolic acid is a potent Hh/GLI signaling inhibitor, it shows an important relationship between Hh/GLI signaling inhibition, the decrease of BCL2, and cytotox...
TN3655	Cimiside E 化合物 TN3655	154822-57-8	98%
TN3655	Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2,...
T16155	MSN-125 化合物 T16155	1592908-16-1	98%
T16155	MSN-125 effectively inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons protect primary neurons against glutamate excitotoxic...
TN3486	Bakkenolide IIIa 化合物 TN3486	915289-60-0	98%
TN3486	Bakkenolide IIIa has antioxidant, and neuroprotective effects, it protects against cerebral damage by inhibiting AKT and ERK1/2 activation and inactivated NF-ÎºB...
TN3806	Dehydroglyasperin C 化合物 TN3806	199331-35-6	98%
TN3806	Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemop...
TN1462	Cajanin 2',4',5-三羟基-7-甲氧基异黄酮	32884-36-9	98%
TN1462	Cajanin has potential hypolipidemic effects,possibly via up-regulating the ABCA1 protein expression,subsequently resulting in increased macrophage cholesterol ef...
T11960	MBM-55 化合物MBM-55	2083622-09-5	99.98%
T11960	MBM-55 是一种有效的中心体相关激酶 2 (NEK2) 抑制剂，IC50 为 1 nM。 MBM-55 通过诱导细胞周期停滞和凋亡有效抑制癌细胞的增殖。
T3881	Vaccarin 王不留行黄酮苷	53452-16-7	99.97%
T3881	Vaccarin 是从王不留行中提取的一种黄酮糖苷，可显著促进伤口愈合以及伤口部位的内皮和成纤维细胞增殖。它通过激活 AMPK 信号通路改善胰岛素抵抗和脂肪变性。
T6S0525	Farrerol 杜鹃素	24211-30-1	99.96%
T6S0525	Farrerol 是一种杜鹃花的生物活性成分，具有抗氧化、抗肿瘤、抗炎、神经保护和肝保护等多种功能。
T4A2399	Cinobufotalin 华蟾毒它灵	1108-68-5	99.94%
T4A2399	Cinobufotalin 是一种从蟾蜍的皮肤分泌物中提取的强心类固醇或丁二烯内酯。它已被用作强心药，利尿药和止血药，也是潜在的抗肺癌药物。
T2492	Perifosine 哌立福新	157716-52-4	99.94%
T2492	Perifosine (KRX-0401) 是一种具有口服活性的烷基磷酸胆碱 Akt 抑制剂，具有抗肿瘤活性。
T6S0781	Phellodendrine 黄柏碱	6873-13-8	99.94%
T6S0781	Phellodendrine (Phallodendrin) 是异喹啉生物碱，是黄柏皮层中的重要特征成分之一。它具有良好的抗氧化，抗炎作用。它通过调节AKT/NF-κB 途径抵抗 AAPH 诱导的氧化应激。
T2P2806	Hederacolchiside A1 革叶常春藤皂苷 A1	106577-39-3	99.92%
T2P2806	Hederacolchiside A1 (Raddeanoside R13) 是从白头翁中分离的一种有抗利什曼原虫和抗肿瘤增殖活性的天然产物。
T13803	N-Oleoyl glycine 化合物N-Oleoyl glycine	2601-90-3	99.92%
T13803	N-Oleoyl glycine 是一种脂氨酸。在 3T3-L1 脂肪细胞中，N-Oleoyl glycine 通过激活CB1受体和Akt 信号通路来刺激脂肪形成。
T6S0619	Pachymic acid 茯苓酸	29070-92-6	99.91%
T6S0619	Pachymic acid (3-O-Acetyltumulosic acid) 是来自茯苓的一种三萜，可抑制Akt 和ERK 信号传导途径。