Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13177L |
Tocainide
|
Sodium Channel | Membrane transporter/Ion channel |
Tocainide 是口服有活性的 sodium channel 阻滞剂,阻断产生疼痛的病灶中(神经膜上)的钠通道。它是利多卡因 (lignocaine) 的伯胺类似物,可用于研究心律不齐。 | |||
T9133 |
Caroverine hydrochloride
Caroverine HCL |
GluR; NMDAR; iGluR | Membrane transporter/Ion channel; Neuroscience |
Caroverine hydrochloride (Caroverine HCL) 是竞争性可逆的NMDA 和AMPA 谷氨酸受体拮抗剂。它也是抗氧化和钙阻滞剂,具有血管舒张作用,可用于内耳耳鸣的研究。 | |||
T27397 |
Gacyclidine
GK 11,OTO311,OTO-311,OTO 311,GK-11 |
NMDAR | Neuroscience |
Gacyclidine (OTO311) 是一种小分子 N-甲基-D-天冬氨酸(NMDA)受体拮抗剂。在耳蜗局部注射加西环定可抑制水杨酸盐引起的耳鸣,可用于治疗脑损伤、脊髓损伤和耳鸣。 | |||
T34609 |
Selurampanel
BGG-492,BGG 492,BGG492 |
iGluR | Membrane transporter/Ion channel; Neuroscience |
Selurampanel (BGG492) 是一种具有口服活性和选择性的竞争性 AMPA 谷氨酸受体拮抗剂,是一种喹唑啉二酮磺酰胺。Selurampanel 可用于研究癫痫、偏头痛和耳鸣。 | |||
T69814 |
Neramexane Free Base
|
||
Neramexane Free Base is a drug related to memantine, which acts as an NMDA antagonist and has neuroprotective effects. It is being developed for various possible applications, including treatment of tinnitus, Alzheimer's disease, drug addiction and as an analgesic. | |||
T70982 |
Gacyclidine hydrochloride
|
||
Gacyclidine hydrochloride is a N-methyl-D-aspartate (NMDA) receptor antagonist potentially for the treatment of tinnitus. | |||
T20962 |
(S)-Baclofen
(+)-Baclofen,(L)-Baclofen |
||
(S)-Baclofen has effects on excitation in the ascending auditory pathway leading to it a potential reagent for the treatment of hyperactive auditory disorders such as hyperacusis and tinnitus. | |||
T72224 | NK1 receptor antagonist 2 | ||
NK1receptor antagonist 2 是一种 NK1受体拮抗剂。NK1receptor antagonist 2 可用于耳鸣和听力损失的研究。 | |||
T69144 | Hexylcaine HCl | ||
Hexylcaine HCl also called cyclaine or osmocaine, is a short-acting local anesthetic. It acts by inhibiting sodium channel conduction. Overdose can lead to headache, tinnitus, numbness and tingling around the mouth and tongue, convulsions, inability to breathe, and decreased heart function. |