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6

抑制剂 & 化合物

2

天然产物

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Cat. No. Product Name Target Signaling Pathways
T2411 Luliconazole

NND 502,卢立康唑

Antibiotic; Antifungal Microbiology/Virology
Luliconazole (NND 502) 是一种咪唑类抗生素,具有广谱抗真菌活性。它可研究皮肤感染。
T27710 K6PC-5

K6PC5,K6PC 5

S1P Receptor GPCR/G Protein
K6PC-5 is a ceramide derivative that acts as an activator of sphingosine kinase 1 (SPHK1), inducing a swift and temporary rise in intracellular calcium levels. With its potential applications in skin diseases associated with abnormal keratinocyte function, as well as in studies on neurodegeneration and virus infection, K6PC-5 presents a promising compound for research purposes.
T15095 Dehydroemetine

Others; Parasite Microbiology/Virology; Others
Dehydroemetine 是一种有效的抗原虫剂,是二盐酸艾美汀的合成类似物,可用于预防和治疗阿米巴感染和疾病,具有治疗伴有皮肤损伤的利什曼原虫感染和耐甲硝唑阿米巴病的作用。
T15734 Lenampicillin hydrochloride

盐酸仑氨苄西林,KBT 1585 hydrochloride

Antibacterial Microbiology/Virology
Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skin
T71860 Ambuic acid

Ambuic acid is a cyclohexanone that has phytopathogenic antifungal, quorum sensing inhibitory, and antibacterial activities. Ambuic acid inhibits the biosynthesis of cyclic peptides involved in quorum sensing, including gelatinase biosynthesis-activating pheromone (GBAP) in E. faecalis, autoinducing peptide I (AIP-I) in S. aureus, and LsrD698 and LsrD826 in L. innocua. It suppresses abcess formation in a mouse model of skin infection induced by methicillin-resistant S. aureus (MRSA) when adminis...
T64692 AMY-101 acetate

Complement component C3 plays a particularly versatile role in this process by keeping the cascade alert, acting as a point of convergence of activation pathways, fueling the amplification of the complement response, exerting direct effector functions, and helping to coordinate downstream immune responses[3]. In C3-/- mice alcohol-induced liver steatosis is absent or strongly reduced after chronic or acute alcohol exposure. This suggests that the complement system and its component C3 contribute...

化合物

Luliconazole
Cat.No: T2411
Synonym: NND 502,卢立康唑
Target: Antibiotic, Antifungal
K6PC-5
Cat.No: T27710
Synonym: K6PC5,K6PC 5
Target: S1P Receptor
Dehydroemetine
Cat.No: T15095
Synonym:
Target: Others, Parasite
Lenampicillin hydrochloride
Cat.No: T15734
Synonym: 盐酸仑氨苄西林,KBT 1585 hydrochloride
Target: Antibacterial
Ambuic acid
Cat.No: T71860
Synonym:
Target:
AMY-101 acetate
Cat.No: T64692
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T0729 Benzyl benzoate

Ascabiol,Novoscabin,Scabitox,苯甲酸苄酯,Benzoic acid benzyl ester

Parasite Microbiology/Virology
Benzyl benzoate (Benzoic acid benzyl ester) 是化妆品中的香料成分,可研究疥疮和蠕形螨相关的炎症性皮肤病。
T6S1572 Sauchinone

ERK; p38 MAPK; NF-κB MAPK; NF-κB
Sauchinone 是一种从Saururus chinensis 中获得的非对映异构的木脂素。它通过抑制I-κBα磷酸化和p65核易位来抑制 LPS 诱导的 iNOS,TNF-α 和 COX-2 表达。它具有抗炎和抗氧化活性。

天然产物

Benzyl benzoate
Cat.No: T0729
Synonym: Ascabiol,Novoscabin,Scabitox,苯甲酸苄酯,Benzoic acid benzyl ester
Target: Parasite
Sauchinone
Cat.No: T6S1572
Synonym:
Target: ERK, p38 MAPK, NF-κB
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