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Search Results for " sedative-hypnotic "

22

抑制剂 & 化合物

4

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T3563	Lvguidingan	Others	Others
	Lvguidingan 是一种抗惊厥药。
T0370	Pheniramine maleate Daneral,Inhiston,Trimetose,马来酸非尼拉敏	5-HT Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Pheniramine maleate (Trimetose) 是一种具有抗组胺和血管扩张特性的烷基胺衍生物，可与组胺 H1 受体结合，从而抑制磷脂酶 A2 和内皮源性松弛因子一氧化氮的产生。
T30248	AZD 3043 AZD-3043,THRX 918661,AZD3043
	AZD 3043 is a propofol derivative which acts as a sedative-hypnotic agent.
T0227	Bromisoval 2-Bromo-N-carbamoyl-3-methylbutanamide,Isobromyl,溴米那,BRN 1773255,Bromovalerylurea,溴米索伐,Bromaral	Others	Others
	Bromisoval (Isobromyl) 具有抗炎活性。
T14314	Apronal Apronalide,Allylisopropylacetylurea,丙戊酰脲	Others	Others
	Apronal (Apronalide) 具有催眠和镇静作用，可用于神经精神疾病的相关研究。
T31724	Etoxybamide	Others	Others
	Etoxybamide 是镇静剂（催眠药）的候选药物。
T10002	(E)-Crotylbarbital Kalypnon	Others	Others
	(E)-Crotylbarbital (Kalypnon) 是Crotylbarbital 的异构体，是一种巴比妥酸衍生物，具有镇静、催眠和抗惊厥的作用。(E)-Crotylbarbital 可用于促进精神安定和睡眠的研究。
T3282	Alimemazine hemitartrate Alimemazine Tartrate,Methylpromazine Tartrate,酒石酸异丁嗪,Trimeprazine tartrate,Trimeprazine hemitartrate	Others	Others
	Alimemazine hemitartrate (Trimeprazine hemitartrate) 是血凝素 (HA)-受体的拮抗剂，也是一种吩噻嗪衍生物，常用作止痒剂。
T0901	Chlorobutanol Chlortran,Chloretone,YM-57158,三氯叔丁醇,Chlorbutol,Chloreton	Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Chlorobutanol (Chlortran) 是一种药物防腐剂，对多种革兰氏阳性和革兰氏阴性细菌以及几种霉菌孢子和真菌具有抗性。它广泛用于食品和化妆品工业，有促进安定、睡眠的作用。
T26948	Capuride NSC-27178,NSC27178,NSC-27690,NSC 27178,NSC27690
	Capuride is a sedative with hypnotic properties and possible anticonvulsant activity.
T26061	Reposal WT-161,Reposamal,Reposal novo,WT161,WT 161
	Reposal is a barbiturate derivative invented in the 1960s in Denmark. It has hypnotic, sedative, and anticonvulsant properties, and was used primarily for the therapy of insomnia.
T13682	Epipregnanolone	Others	Others
	Epipregnanolone is an endogenous neurosteroid with hypnotic and sedative effects.
T34771	Taglutimide
	Taglutimide is a sedative-hypnotic derivative of glutarimide.
T24201	JM-1232 JM 1232,MR 04A3,MR-04A3,MR04A3
	JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic.
T30945	Cinolazepam Gerodorm,OX-373
	Cinolazepam is a benzodiazepine derivative drug.It has a powerful sedative effect, so it is mainly used as a hypnotic.
T27007	Chlormethiazole edisylate Clomethiazole ethanedisulfonate,Clomethiazole edisylate,Heminevrin,Hemithiamine,Distraneurin
	Chlormethiazole edisylate is a positive allosteric modulator of the GABAA receptor. Chlormethiazole edisylate is a sedative and hypnotic.
T28378	PF-0713 PF 0713,PF713
	PF 0713, a GABAA receptor agonist, is used as an intravenous sedative-hypnotic for general anaesthesia, ICU sedation, procedural sedation, chemotherapy.
T40205	Posovolone Co 134444
	Posovolone (Co 134444), an orally active neuroactive steroid with sedative-hypnotic properties, exhibits anticonvulsant and anxiolytic-like activities, alongside ataxic effects.
T23604	Acebrochol
	Acebrochol is a neuroactive steroid. It may act as a sedative and hypnotic, by the mechanism of altering ligand-gated ion channels and cell surface receptors.
T69434	Methapyrilene fumarate
	Methapyrilene fumarate is a histamine H1 antagonist with sedative action used as a hypnotic and in allergies. It is a hepatocarcinogen in sufficiently high doses, inducing mutations through an indirect genotoxic mechanism; e.g., via an oxidative mechanism or interaction with chromosomal proteins.
T68111	nabitan
	Nabitan 是δ -9-四氢大麻酚的类似物，根据其在动物中的镇静、催眠和镇痛特性而被选择。
T78111	NCS-382 sodium	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	NCS-382 (sodium) 为一种高效GABA受体拮抗剂，具备抗镇静及抗催眠特性，适用于神经系统疾病研究。

化合物

Cat.No: T3563

Target: Others

Pheniramine maleate

Cat.No: T0370

Synonym: Daneral,Inhiston,Trimetose,马来酸非尼拉敏

Target: 5-HT Receptor, Histamine Receptor

Cat.No: T30248

Synonym: AZD-3043,THRX 918661,AZD3043

Cat.No: T0227

Synonym: 2-Bromo-N-carbamoyl-3-methylbutanamide,Isobromyl,溴米那,BRN 1773255,Bromovalerylurea,溴米索伐,Bromaral

Target: Others

Cat.No: T14314

Synonym: Apronalide,Allylisopropylacetylurea,丙戊酰脲

Target: Others

Cat.No: T31724

Target: Others

(E)-Crotylbarbital

Cat.No: T10002

Synonym: Kalypnon

Target: Others

Alimemazine hemitartrate

Cat.No: T3282

Synonym: Alimemazine Tartrate,Methylpromazine Tartrate,酒石酸异丁嗪,Trimeprazine tartrate,Trimeprazine hemitartrate

Target: Others

Cat.No: T0901

Synonym: Chlortran,Chloretone,YM-57158,三氯叔丁醇,Chlorbutol,Chloreton

Target: Antibacterial, Antibiotic, Antifungal

Cat.No: T26948

Synonym: NSC-27178,NSC27178,NSC-27690,NSC 27178,NSC27690

Cat.No: T26061

Synonym: WT-161,Reposamal,Reposal novo,WT161,WT 161

Epipregnanolone

Cat.No: T13682

Target: Others

Cat.No: T34771

Cat.No: T24201

Synonym: JM 1232,MR 04A3,MR-04A3,MR04A3

Cat.No: T30945

Synonym: Gerodorm,OX-373

Chlormethiazole edisylate

Cat.No: T27007

Synonym: Clomethiazole ethanedisulfonate,Clomethiazole edisylate,Heminevrin,Hemithiamine,Distraneurin

Cat.No: T28378

Synonym: PF 0713,PF713

Cat.No: T40205

Synonym: Co 134444

Cat.No: T23604

Methapyrilene fumarate

Cat.No: T69434

Cat.No: T68111

Cat.No: T78111

Target: GABA Receptor

Cat. No.	Product Name	Target	Signaling Pathways
T4S0675	Polygalasaponin V 瓜子金皂苷V,瓜子金皂苷 V	Others	Others
	Polygalasaponin V 是一种三萜皂苷，分离自Polygala japonica 的地上部分。其中Polygala japonica 是民间的药用植物，在中国南方用作祛痰、抗菌、抗炎、抗抑郁药。
T7646	Alloepipregnanolone	Endogenous Metabolite	Metabolism
	Alloepipregnanolone 是具有促进安定和睡眠的孕酮，可干扰乙醇抗焦虑作用的快速耐受。
T8297	Gomisin N	Apoptosis	Apoptosis
	Gomisin N 是从五味子中分离得到的一种天然产物，有镇静和催眠生物活性。它具有用于治疗过敏和抑制癌症增殖和诱导细胞凋亡的潜力。
T37709	2,2,2-Trichloroethanol	Potassium Channel; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism
	2,2,2-Trichloroethanol 是非经典的 K2P 通道 TREK-1和 TRAAK 的激动剂。

天然产物

Polygalasaponin V

Cat.No: T4S0675

Synonym: 瓜子金皂苷V,瓜子金皂苷 V

Target: Others

Alloepipregnanolone

Cat.No: T7646

Target: Endogenous Metabolite

Cat.No: T8297

Target: Apoptosis

2,2,2-Trichloroethanol

Cat.No: T37709

Target: Potassium Channel, Endogenous Metabolite

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