3
3
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10809 |
CHPG
|
Others | Others |
CHPG is a selective agonist of mGluR5. In BV2 microglial cells, it attenuates SO2-induced oxidative stress and inflammation through the TSG-6/NF-κB pathway. | |||
T10809L |
CHPG hydrochloride
CHPG hydrochloride(170846-74-9 Free base) |
ERK; NF-κB; GluR | MAPK; Neuroscience; NF-κB |
CHPG hydrochloride 是 mGluR5 的选择性激动剂。 | |||
T10808 |
CHPG sodium salt
|
NF-κB; GluR | Neuroscience; NF-κB |
CHPG sodium salt 是 mGluR5 的选择性激动剂,可激活 ERK 和 Akt 信号通路。 CHPG 钠盐可用于创伤性脑损伤的研究。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN6714 |
Geranylgeraniol
FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,香叶基香叶醇,CJ-24095 |
Apoptosis | Apoptosis |
Geranylgeraniol (FT0626663) 是一种类异戊二烯,存在于水果、蔬菜和谷物中,包括大米。 Geranylgeraniol (FT0626663) 抑制生长并诱导各种肿瘤细胞的凋亡。 Geranylgeraniol (FT0626663) 保护单核细胞免受他汀类药物诱导的细胞毒性并抑制分枝杆菌的生长。 | |||
T82211 |
Herpotrichone B
|
||
Herpotrichone B exhibits potent anti-neuroinflammatory activity in BV-2 microglial cells induced by lipopolysaccharide (LPS), with a half-maximal inhibitory concentration (IC50) of 0.11μM. | |||
TN5248 |
Voleneol
|
NOS; COX; Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
1β,6α-Dihydroxyeudesm-4(15)-ene (Voleneol,DE) can attenuate the lipopolysaccharide (LPS)-induced inflammation in BV2 microglial cells, it also can dose-dependently suppress the protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenas |