9
1
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0435 |
Sulfinpyrazone
(+/-)-Sulfinpyrazone,G-28315,苯磺保泰松,NSC 75925 |
COX | Immunology/Inflammation; Neuroscience |
Sulfinpyrazone (NSC-75925) 是一种口服有效的尿酸剂,具有抗血栓和血小板抑制作用。它可作用于慢性和间歇性痛风性关节炎。 | |||
T4509 |
Inositol nicotinate
Inositol niacinate,Hexanicotol,Myo-Inositol hexanicotinate,Mesotal,肌醇烟酸酯,Dilexpal,Inositol hexanicotinate |
Others | Others |
Inositol nicotinate (Mesotal) 是一种血管扩张剂,可用于研究外周动脉疾病。 | |||
T1182 |
Levocarnitine propionate hydrochloride
Propionyl-L-carnitine hydrochloride,L-Propionylcarnitine chloride,丙酰左旋肉碱盐酸盐,ST-261,丙酰肉碱盐酸盐 |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Levocarnitine propionate hydrochloride (ST-261) 可用于肾功能恶化,充血性心脏衰竭,间歇性跛行等疾病的研究。 | |||
T21460 |
Teriparatide acetate
hPTH 1-34 (acetate salt),Parathar acetate,Forteo,醋酸立特帕肽 |
Others | Others |
Teriparatide acetate (Forteo) 是一种 PHT 激动剂,在 HEK293 细胞中的 IC50 为 2 nM。Teriparatide acetate 是一种重组形式的甲状旁腺激素。它是一种有效的合成代谢(即骨骼生长)剂,用于治疗某些形式的骨质疏松症。间歇使用特立帕肽比破骨细胞更能激活成骨细胞,从而导致骨骼整体增加。 | |||
T28296 |
Parogrelil hydrochloride
INDI-702,NM-702,NT-702,NM702,INDI702 |
||
Parogrelil is a phosphodiesterase (PDE3/PDE5A) inhibitor potentially for the treatment of intermittent. Parogrelil suppress the asthmatic response in guinea pigs, with both bronchodilating and anti-inflammatory effects. Parogrelil improves reduced walking | |||
T39123 |
Givosiran
ALN-AS1,Givosiran |
||
Givosiran (ALN-AS1) is a small interfering RNA (siRNA) compound that specifically targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA (mRNA) to downregulate its expression. By doing so, Givosiran effectively inhibits the accumulation of neurotoxic δ-aminolevulinic acid and porphobilinogen levels. This compound holds significant potential for further research on acute intermittent porphyria. | |||
T36827 |
Acetoacetyl Coenzyme A (sodium salt hydrate)
Acetoacetyl-CoA |
||
Acetoacetyl-coenzyme A (acetoacetyl-CoA) is a precursor to HMG-CoA in the isoprenoid pathway.[1],[2] It is reversibly converted to acetyl-CoA by acetoacetyl-CoA thiolase in the mitochondria. Acetoacetyl-CoA thiolase (T2) deficiency results in a build-up of ketone bodies leading to intermittent ketoacidosis.[3],[4] Acetoacetyl-CoA is also an intermediate in the microbial biosynthesis of polyhydroxybutyrate.[5] | |||
T35445 |
1-Stearoyl-3-Oleoyl-rac-glycerol
|
||
1-Stearoyl-3-oleoyl-rac-glycerol is a diacylglycerol that contains stearic acid at the sn-1 position and oleic acid at the sn-3 position. Intermittent fasting decreases skeletal muscle and hepatic levels of 1-stearoyl-3-oleoyl-rac-glycerol in New Zealand obese (NZO) mice.1 The concentration of 1-stearoyl-3-oleoyl-rac-glycerol decreases from 4.59 to 1.88% during the dry-curing process of Iberian ham.2References1. Baumeier, C., Kaiser, D., Heeren, J., et al. Caloric restriction and intermittent fa... | |||
T71300 |
Pentoxifylline-d6
|
||
Pentoxifylline-d6 is intended for use as an internal standard for the quantification of pentoxifylline by GC- or LC-MS. Pentoxifylline is a hemorrheologic agent. It increases the deformability of washed isolated human erythrocytes when used at a concentration of 100 µM. Pentoxifylline (1, 2, and 3 mM) inhibits ADP-induced platelet aggregation in isolated human whole blood. It inhibits thrombus formation induced by ADP in a hamster cheek pouch model when administered at doses of 5, 10, and 20 mg/... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0070 |
Pentoxifylline
Oxpentifylline,PTX,己酮可可碱,BL-191 |
HIV Protease; PDE; Adenosine Receptor; Autophagy | Autophagy; GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome |
Pentoxifylline (PTX) 是一种具有口服活性的磷酸二酯酶非选择性抑制剂,具有免疫调节、抗炎、抗纤溶、抗增殖和血液流变学改善作用。它可研究周围血管疾病、脑血管疾病和其他一些涉及局部微循环缺陷的疾病。 |