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6

抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T20539 Pirimiphos-methyl

R 33986,甲基嘧啶磷,AI3-27699,Caswell No. 334B,PP511,Actelic

AChE; Parasite Microbiology/Virology; Neuroscience
Pirimiphos-methyl (AI3-27699) 是一种速效有机磷杀虫剂和杀螨剂,对目标生物的乙酰胆碱酯酶有抑制作用。甲基嘧啶磷常用于农粮贮藏过程中甲虫、鼻甲虫、飞蛾和蝽蛄的防治。
T35502 δ7-Avenasterol

δ7-Avenasterol is a phytosterol that has been found in a variety of plant oils and grains, including olive and soybean oils and wheat, oats, and rye, and has antioxidant activities.1,2It reduces temperature-induced oxidation of safflower oil.3
T75392 Lichenase

Lichenase (endo-1,3:1,4-β-D-Glucanase) 是一种特异性内切-(1-3),(1-4)-β-D-葡聚糖 4-葡聚糖水解酶。Lichenase 溶解谷物中的 β-葡聚糖并产生低聚糖 (GOS)。Lichenase 可用于降解细胞壁中的多糖。
T37458 C18 Phytoceramide (t18:0/18:0)

C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in S. cerevisiae, wheat grains, and the stratum corneum layer of mammalian epidermis. Cer(t18:0/18:0) is composed of a phytosphingosine backbone amine-linked to a C18 fatty acid chain. Cer(t18:0/18:0) has a role in regulation of apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain. It also inhibits expression of the allergic cytokines IL-4, TN...
T35517 4-deoxy Nivalenol-13C15

4-deoxy Nivalenol-13C15

4-deoxy Nivalenol-13C15is intended for use as an internal standard for the quantification of 4-deoxy nivalenol by GC- or LC-MS. 4-deoxy Nivalenol is a trichothecene mycotoxin that has been found inFusarium.1It binds to eukaryotic ribosomes and inhibits protein synthesis in mice when administered at doses ranging from 5 to 25 mg/kg. 4-deoxy Nivalenol (0.1 and 0.2 mg/kg) induces emesis in pigs and decreases feed consumption in pigs when administered at a dose of 40 ppb in the diet.2It induces leth...
T35775 HT-2 Toxin-13C22

HT-2 Toxin-13C22

HT-2 toxin-13C22is intended for use as an internal standard for the quantification of HT-2 toxin by GC- or LC-MS. HT-2 toxin is a type A trichothecene mycotoxin and an active, deacetylated metabolite of the trichothecene mycotoxin T-2 toxin .1,2Like T-2 toxin, HT-2 toxin inhibits protein synthesis and cell proliferation in plants.2HT-2 toxin also reduces viability of HepG2, A549, HEp-2, Caco-2, A-204, U937, Jurkat, and RPMI-8226 cancer cells with IC50values ranging from 3.1 to 23 ng/ml and human...

化合物

Pirimiphos-methyl
Cat.No: T20539
Synonym: R 33986,甲基嘧啶磷,AI3-27699,Caswell No. 334B,PP511,Actelic
Target: AChE, Parasite
δ7-Avenasterol
Cat.No: T35502
Synonym:
Target:
Lichenase
Cat.No: T75392
Synonym:
Target:
C18 Phytoceramide (t18:0/18:0)
Cat.No: T37458
Synonym:
Target:
4-deoxy Nivalenol-13C15
Cat.No: T35517
Synonym: 4-deoxy Nivalenol-13C15
Target:
HT-2 Toxin-13C22
Cat.No: T35775
Synonym: HT-2 Toxin-13C22
Target:
Cat. No. Product Name Target Signaling Pathways
T16527 Phytic acid dodecasodium salt hydrate

植酸十二钠盐,myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate,Inositol hexaphosphate dodecasodium salt hydrate

Others; Xanthine Oxidase; Endogenous Metabolite Metabolism; Others
Phytic acid dodecasodium salt hydrate (myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate) 是种子和谷物的磷储存化合物。 Phytic acid dodecasodium salt hydrate 抑制酶促超氧化物源黄嘌呤氧化酶,IC50 为 6 mM,并具有抗氧化、神经保护和抗炎作用。
T2803 Monocrotaline

野百合碱,Crotaline

TGF-beta/Smad Stem Cells
Monocrotaline (Crotaline) 是一种吡咯里西啶生物碱,从猪屎豆植物的种子中提取得到,可诱导啮齿动物产生肺动脉高血压。
TN6714 Geranylgeraniol

FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,香叶基香叶醇,CJ-24095

Apoptosis Apoptosis
Geranylgeraniol (FT0626663) 是一种类异戊二烯,存在于水果、蔬菜和谷物中,包括大米。 Geranylgeraniol (FT0626663) 抑制生长并诱导各种肿瘤细胞的凋亡。 Geranylgeraniol (FT0626663) 保护单核细胞免受他汀类药物诱导的细胞毒性并抑制分枝杆菌的生长。
T9675 α-Tocotrienol

Endogenous Metabolite Metabolism
α-Tocotrienol 是维生素 E 的一种亚型,存在于蔬菜、水果、种子、坚果、谷物和油脂中。α-Tocotrienol 是抗氧化剂,可以降低胆固醇和其他脂类,也是神经保护和抗癌剂,在心血管疾病的保护中发挥作用。
T0019 Betaine chloride

Betaine hydrochloride,盐酸甜菜碱

Others; Chloride channel; Endogenous Metabolite Membrane transporter/Ion channel; Metabolism; Others
Betaine chloride (Betaine hydrochloride) 是一种天然化合物,在许多食物中能够发现,也是能够维持正常 DNA 甲基化模式的特性甲基供体。
T3S0309 D(+)-Raffinose pentahydrate

D-Raffinose pentahydrate,Raffinose,D(+)-五水棉子糖,五水棉子糖

Others; Endogenous Metabolite Metabolism; Others
D(+)-Raffinose pentahydrate (D-Raffinose pentahydrate) 是果糖,半乳糖和葡萄糖组成的三糖,天然存在于各种蔬菜和谷物中。D(+)-Raffinose pentahydrate 是一种功能性低聚糖。
T13391 Zearalanone

Others Others
Zearalenone is a nonsteroidal estrogenic mycotoxin produced by Fusarium species, which colonizes several grains.
T15357 Fumonisin B2

伏马菌素B2

Others Others
Fumonisin B2 is a mycotoxin produced by Fusarium moniliforme in various grains. It also is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase). Which disrupts de novo sphingolipid biosynthesis.
T80718 Z-Pro-Ala

Z-Pro-Ala是从小麦(Triticum aestivum L)的谷物和叶子中分离得到的酸性羧肽酶。
T13053 T-​2 Toxin

T-2 Mycotoxin

Others Others
T- 2 Toxin is a toxic trichothecene mycotoxin produced by various Fusarium species in feedstuffs and cereal grains,( LD50 are 5.2 and 1.5 mg/kg BWa in mice and rats,respectively ).

天然产物

Phytic acid dodecasodium salt hydrate
Cat.No: T16527
Synonym: 植酸十二钠盐,myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate,Inositol hexaphosphate dodecasodium salt hydrate
Target: Others, Xanthine Oxidase, Endogenous Metabolite
Monocrotaline
Cat.No: T2803
Synonym: 野百合碱,Crotaline
Target: TGF-beta/Smad
Geranylgeraniol
Cat.No: TN6714
Synonym: FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,香叶基香叶醇,CJ-24095
Target: Apoptosis
α-Tocotrienol
Cat.No: T9675
Synonym:
Target: Endogenous Metabolite
Betaine chloride
Cat.No: T0019
Synonym: Betaine hydrochloride,盐酸甜菜碱
Target: Others, Chloride channel, Endogenous Metabolite
D(+)-Raffinose pentahydrate
Cat.No: T3S0309
Synonym: D-Raffinose pentahydrate,Raffinose,D(+)-五水棉子糖,五水棉子糖
Target: Others, Endogenous Metabolite
Zearalanone
Cat.No: T13391
Synonym:
Target: Others
Fumonisin B2
Cat.No: T15357
Synonym: 伏马菌素B2
Target: Others
Z-Pro-Ala
Cat.No: T80718
Synonym:
Target:
T-​2 Toxin
Cat.No: T13053
Synonym: T-2 Mycotoxin
Target: Others
TargetMol Loading
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