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631

抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T39629 BRD4 ligand-Linker Conjugate 1

BRD4 ligand-Linker Conjugate 1

BRD4 Ligand-Linker Conjugate 1 is a compound consisting of a ligand and a linker, specifically designed to bind to the target protein BRD4. This conjugate serves as a valuable tool for synthesizing PROTACs, molecules utilized for targeted protein degradation.
T40140 Zanamivir-Cholesterol Conjugate

Zanamivir-cholesterol conjugate is an extended-duration neuraminidase inhibitor highly effective against drug-resistant influenza strains.
T37797 Coumarin-Quinone Conjugate

Coumarin-quinone conjugate is a fluorescent substrate for NADH:ubiquinone oxidoreductases.1It is comprised of a coumarin fluorophore conjugated to a ubiquinone analog that can be reduced by NADH:ubiquinone oxidoreductases. It has been used to measure the kinetic parameters of apoptosis-inducing factor mitochondria-associated 2/ferroptosis suppressor protein 1 (AIFM2/FSP1). 1.Doll, S., Freitas, F.P., Shah, R., et al.FSP1 is a glutathione-independent ferroptosis suppressorNature575(7784)693-698(20...
T36314 Wortmannin-Rapamycin Conjugate

Phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) act synergistically in promoting cancer. Wortmannin is a potent inhibitor of PI3K enzymes, while rapamycin blocks mTOR Complex 1 TORC1. Wortmannin-rapamycin conjugate consists of analogs of 17-hydroxy wortmannin and rapamycin conjugated via a prodrug linker. Hydrolysis of the prodrug linker in vivo releases the inhibitors. The wortmannin-rapamycin conjugate inhibits the growth of HT-29 colon tumors and A498 renal tumors in...
T11079 NMI 8739

n-docosahexaenoyl dopamine,Dha-DA conjugate

Dopamine Receptor GPCR/G Protein; Neuroscience
NMI 8739 (n-docosahexaenoyl dopamine) 是 D2 自身受体的激动剂。 NMI 8739 减少 NO 的产生并引起 CCL-20、MCP-1 和 IL-6 释放的浓度依赖性抑制。
T36853 Phalloidin-Tetramethylrhodamine Conjugate

Phalloidin-retramethylrhodamine conjugate is an orange fluorescent probe (ex/em = 546/575 nm) that selectively binds to F-actin. It can be used to localize actin filaments in living or fixed cells, as well as for visualizing individual actin filaments in vitro.
T36852 Phalloidin-AMCA Conjugate

Phalloidin-AMCA conjugate is a blue fluorophore that specifically labels filamentous actin (F-actin). It consists of aminomethylcoumarin (AMCA; ex/em max = 350/450 nm) conjugated with phalloidin , a mycotoxin that binds F-actin. Phalloidin-AMCA conjugate is used in fixed and permeabilized tissue sections, cell cultures, or cell-free experiments.
T35980 Bilirubin Conjugate (sodium salt)

Bilirubin conjugate is a stable, water-soluble ditaurate derivative of bilirubin meant to mimic endogenous bilirubin glucuronide derivatives. In vivo, bilirubin circulates in the plasma and is taken up by hepatocytes and conjugated to one or two glucuronic acids in a reaction catalyzed by UDP glucuronidase to form bilirubin mono or diglucuronide. This water-soluble form is then excreted from the liver in bile in the feces or is converted to urobilinogen and excreted in the urine. In addition to ...
T77496L AZD 1775 Linker Conjugate 1 TFA

AZD 1775 Linker Conjugate 1 TFA( 2101954-45-2 Free base)

AZD 1775 Linker Conjugate 1 TFA 是一种参与泛素酶靶向嵌合体实验的化合物。
T17943 FAK ligand-Linker Conjugate 1

Others Others
FAK ligand-Linker Conjugate 1 is a chemical compound designed to facilitate PROTAC-mediated protein degradation. This compound consists of a ligand specifically targeting FAK and a PROTAC linker module, which acts as a recruitment agent for E3 ligases including VHL, CRBN, MDM2, and IAP[1].
T18054 K-Ras ligand-Linker Conjugate 1

Others Others
K-Ras ligand-Linker Conjugate 1 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker, facilitating the recruitment of E3 ligases VHL, CRBN, MDM2, and IAP. It can be utilized in the synthesis of PROTAC K-Ras Degrader-1, a highly effective K-Ras degrader that achieves ≥70% degradation efficacy in SW1573 cells[1].
T18059 K-Ras ligand-Linker Conjugate 6

Others Others
K-Ras ligand-Linker Conjugate 6 is a chemical compound that combines a ligand for K-Ras recruiting moiety and a PROTAC linker. This compound can recruit E3 ligases, including VHL, CRBN, MDM2, and IAP. K-Ras ligand-Linker Conjugate 6 is particularly useful in the synthesis of PROTAC K-Ras Degrader-1, a highly effective K-Ras degrader that achieves ≥70% degradation efficacy in SW1573 cells[1].
T18058 K-Ras ligand-Linker Conjugate 5

Others Others
K-Ras ligand-Linker Conjugate 5 is a chemical compound that combines a ligand for the K-Ras recruiting moiety with a PROTAC linker. This linker is responsible for recruiting E3 ligases such as VHL, CRBN, MDM2, and IAP. The K-Ras ligand-Linker Conjugate 5 plays a crucial role in the synthesis of PROTAC K-Ras Degrader-1, a highly potent K-Ras degrader. In SW1573 cells, this degrader exhibits an impressive degradation efficacy of ≥70% [1].
T18056 K-Ras ligand-Linker Conjugate 3

Others Others
K-Ras ligand-Linker Conjugate 3 (Compound 001371) is a chemical compound that consists of a ligand for K-Ras recruiting moiety and a PROTAC linker, responsible for recruiting E3 ligases (e.g., VHL, CRBN, MDM2, and IAP). This compound is essential in the synthesis of PROTAC K-Ras Degrader-1, a potent PROTAC K-Ras degrader that demonstrates a degradation efficacy of ≥70% in SW1573 cells[1].
T18055 K-Ras ligand-Linker Conjugate 2

Others Others
K-Ras ligand-Linker Conjugate 2 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker. This compound is capable of recruiting E3 ligases like VHL, CRBN, MDM2, and IAP. It is utilized in the synthesis of PROTAC K-Ras Degrader-1, which is a highly effective PROTAC K-Ras degrader with a degradation efficacy of ≥70% in SW1573 cells[1].
T18057 K-Ras ligand-Linker Conjugate 4

Others Others
K-Ras ligand-Linker Conjugate 4 is a chemical compound that combines a ligand for K-Ras recruiting moiety with a PROTAC linker. This linker is responsible for recruiting E3 ligases such as VHL, CRBN, MDM2, and IAP. The compound has the potential to be used in the synthesis of PROTAC K-Ras Degrader-1, a powerful degrader of K-Ras that has been shown to exhibit a degradation efficacy of ≥70% in SW1573 cells[1].
T17742 DBCO-Biotin

Azadibenzocyclooctyne-Biotin conjugate

DBCO-Biotin (Azadibenzocyclooctyne-Biotin conjugate) 是一种基于烷基链的 PROTAC linker。
T18063 Lenalidomide-acetylene-C5-COOH

Cereblon ligand-linker Conjugate

Others Others
Lenalidomide-acetylene-C5-COOH (compound 43; Cereblon ligand-linker Conjugate) serves as a Lenalidomide-based Cereblon ligand that facilitates the recruitment of the CRBN protein. This compound can be connected to the protein's ligand through a linker, resulting in the formation of PROTAC[1].
T39703 ATRA-biotin

ATRA-biotin,Biotin-ATRA-conjugate

ATRA-biotin is a biotin-conjugated form of all-trans retinoic acid (ATRA). It is utilized for the purpose of tracking ATRA within cells or specific tissues.
T34788 Taurolithocholic acid

Lithocholyltaurine,Lithocholic acid taurine conjugate

Taurolithocholic acid is a cholagogue and choleretic.
T33243 MC-Val-Cit-PAB-VX765

Belnacasan-conjugate,VX765-conjugate,MC-Val-Cit-PABC-VX765

MC-VAL-CIT-PAB-VX765 or MC-VAL-CIT-PABC-VX765 is a VX765 derivative that can be conjugated to antibodies, proteins, or polymers for targeted drug delivery. MC-Val- CIT -PAB is a cathepsin cleavable ADC connector, which has been widely used in the preparat
T77861 XMT-1519 conjugate-1

XMT-1519 conjugate-1(化合物31)是一种与HER-2单克隆抗体XMT-1519的连接体,应用于ADC合成以增强其抗肿瘤活力。
T23950 Dacomitinib metabolite M2

Dacomitinib cysteine conjugate,UNII-SOA52D3NLL

Dacomitinib metabolite M2 is also known as Dacomitinib cysteine conjugate. Dacomitinib inhibits both the wild-type (WT) EGFR and EGFR T790M.
T27200 DOX−NOP1 HCl

doxorubicin-NOP1 conjugate,doxorubicin-NOP1 HCl,DOX−NOP1 Hydrochloride

DOX−NOP1 is a molecular hybrid covalently joining doxorubicin (DOX) and NOP1. DOX−NOP1 showed similar increased toxicity toward resistant cancer cells and, in addition, lower cardiotoxicity than DOX.
T74975 Zn-DPA-maytansinoid conjugate 1

Zn-DPA-maytansinoid conjugate 1 为一种靶向小分子免疫检查点的类美坦素偶联物。其能持续诱导肿瘤生长消退,并激活肿瘤微环境(TME),转化为“炎热肿瘤”。
T33406 MitoE10

Mito E10,Vitaman E-triphenylphosphonium conjugate,MitoE-10

MitoE10 is an effective mitochondrial targeting antioxidant.
T75383 Anti-α-Tubulin Antibody, AF555 conjugate

Anti-α-Tubulin Antibody, AF555 conjugate 为小鼠来源α-tubulin 单克隆抗体与红色荧光染料Alexa Fluor 555 结合的复合物,专于微管蛋白检测使用(Ex/Em:554/567 nm)。
T9520 ALC-0159

Others Others
ALC-0159 是聚乙二醇的脂质结合物,是一种疫苗赋形剂。
T14349 Auristatin F

Microtubule Associated Cytoskeletal Signaling
Auristatin F 是一种有效的微管抑制剂和血管损伤剂。 Auristatin F 可用于抗体-药物偶联物。
T8316 1V209

TLR7 agonist T7

TLR Immunology/Inflammation
1V209 (TLR7 agonist T7) 是一种 Toll 样受体 7 (TLR7) 激动剂,可与各种多糖缀合,以改善其水溶性,增强功效并保持低毒性,具有抗肿瘤作用。
T28289 Paclitaxel-SMCC

SMCC taxol, Taxol-SMCC, Taxol SMCC,Paclitaxel with SMCC linker,SMCC-Taxol,Paclitaxel ADC conjugate.

Paclitaxel-SMCC is a paclitaxel derivative with a SMCC linker. (Succinimidyl-4-( N -maleimidomethyl)cyclohexane-1-carboxylate). Paclitaxel-SMCC can be used to synthesize Paclitaxel bioconjugates with enzymes, antobodies, antigens and other biopolymers. Pa
T83858 Tauro-Obeticholic Acid sodium

Tauro-6-Ethylchenodeoxycholic Acid,Tauro-6-Ethyl-CDCA,Obeticholic Acid Taurine Conjugate,Tauro-OCA,T-ECDCA

陶氏奥贝胆酸是奥贝胆酸的活性代谢物,属于法尼索德X受体(FXR)激动剂并且是熊脱氧胆酸的半合成衍生物。陶氏奥贝胆酸通过在肝脏中与牛磺酸结合形成,但可以通过肠道微生物被再次转换回奥贝胆酸。
T21408 DM1-SMe

DM1-SSMe

Microtubule Associated Cytoskeletal Signaling
DM1-SMe (DM1-SSMe) 是美登木素微管的有效抑制剂。 DM1-SMe 的效力是母体药物美登素的 3 至 10 倍,在一组人类肿瘤细胞系中,DM1-SMe 的 IC50 为 0.003 至 0.01 nM。
T18479 NH-bis(C1-Boc)

亚氨基二乙酸二异丁酯

Others Others
Boc-NH-C6-Br 是一种不可切割的接头,用于抗体-药物偶联物。
T70005 LY3325656

LY3325656 is a GPR142 agonist suitable for clinical testing in human. LY3325656 demonstrated anti-diabetic benefits in pre-clinical studies and ADME/PK properties suitable for human dosing. LY3325656 is the first GPR142 agonist molecule advancing to phase 1 clinic trials for the treatment of Type 2 diabetes.
T17727 CCK2R Ligand-Linker Conjugates 1

Others Others
CCK2R Ligand-Linker Conjugate 1 is a hydrophilic peptide linker that conjugates to the cytotoxic antimicrotubule agents Desacetyl Vinblastine Hydrazide (DAVBH) and Tubulysin B Hydrazide (TubBH) as ligand-linker conjugates[1].
T39609 cIAP1 Ligand-Linker Conjugates 16

cIAP1 Ligand-Linker Conjugates 16

cIAP1 Ligand-Linker Conjugates 16 refers to a specific type of ligase ligand-linker conjugate, possessing the ability to engage with E3 ligases, which finds application in the synthesis of PROTACs.
T7757 Cereblon Ligand -Linker Conjugates 2 TFA

Cereblon Ligand -Linker Conjugates 2 TFA 是一种 E3 连接酶配体- linker 偶联物,包含基于 Thalidomide 的 cereblon 配体和 linker。
T17886 cIAP1 Ligand-Linker Conjugates 15 hydrochloride

E3 ligase Ligand-Linker Conjugates 34 hydrochloride

Others Others
cIAP1 Ligand-Linker Conjugates 15 hydrochloride is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is useful in the development of SNIPERs[1].
T17894 cIAP1 Ligand-Linker Conjugates 3

E3 ligase Ligand-Linker Conjugates 40

Others Others
cIAP1 Ligand-Linker Conjugates 3 are chemical compounds comprising an IAP ligand designed specifically for the E3 ubiquitin ligase and a PROTAC linker. These conjugates, denoted as cIAP1 Ligand-Linker Conjugates 3, find utility in the design of SNIPERs, short for Specific and Non-genetic IAP-dependent Protein Erasers [1].
T19988 Conjugated Estrogen sodium

Conjugated estrogens,Conest,HSDB 3076,Kestrin,Estrogens, conjugated,TAG-39

Conjugated estrogens are medicine that contains a mixture of estrogen hormones. It is used to treat moderate to severe hot flashes, changes in and around the vagina, and other symptoms of menopause or low amounts of estrogen. Conjugated estrogens tablet i
T74876 GalNAc unconjugated/naked Inclisiran

GalNAc unconjugated/naked Inclisiran 是一种未偶联GalNAc的双链小干扰RNA (siRNA) 分子,具有抑制PCSK-9转录功能。该化合物主要应用于高脂血症及心血管疾病(CVD)的研究领域。
T35854 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)

9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat.1It binds to peroxisome proliferator-activated receptor α (PPARα; IC50= 140 nM) and activates the receptor in a reporter assay using COS-1 cells expressing mouse PPARα when used at a concentration of 100 μM.29(Z),11(E)-Conjugated linoleic acid inhibits TNF-α-inducedGLUT4expression and increases insulin-stimulated glucose transport in 3T3-L1 adipocytes.3Dietary administration of 9(Z)11(E)-co...
T18873 VHL Ligand-Linker Conjugates 17

Others Others
VHL Ligand-Linker Conjugates 17 are chemical compounds that consist of a VHL ligand specialized for the E3 ubiquitin ligase, as well as a PROTAC linker. These conjugates are utilized in the synthesis of various PROTACs, including the notable ARD-266. ARD-266 is an exceptionally effective androgen receptor (AR) PROTAC degrader[1].
T17895 cIAP1 Ligand-Linker Conjugates 1

E3 ligase Ligand-Linker Conjugates 41

Others Others
cIAP1 Ligand-Linker Conjugates 1 is composed of an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 1, is particularly useful in the development of SNIPERs[1].
T17364 AhR Ligand-Linker Conjugates 1

E3 Ligase Ligand-Linker Conjugates 57

Others Others
AhR Ligand-Linker Conjugates 1, also known as E3 Ligase Ligand-Linker Conjugates 57, is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a SNIPER linker. It is specifically designed to be used in the development of SNIPER[1].
T17884 cIAP1 Ligand-Linker Conjugates 11 Hydrochloride

E3 ligase Ligand-Linker Conjugates 33 Hydrochloride

Others Others
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride is a chemical compound consisting of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. It is primarily utilized in the development of SNIPERs, a molecular tool for targeted protein degradation[1].
T17898 cIAP1 Ligand-Linker Conjugates 7

E3 ligase Ligand-Linker Conjugates 44

Others Others
cIAP1 Ligand-Linker Conjugates 7 is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a PROTAC linker. It is utilized in the design of SNIPERs[1].
T21009 Conjugated linoleic acid

Conjugated linoleic acid, a naturally occurring fatty acid, is present in ruminant meat and dairy products and is produced by a bio-hydrogenation process in the rumen. In this case, the predominant isomer formed is 9cis, 11trans.
T17899 cIAP1 Ligand-Linker Conjugates 9

E3 ligase Ligand-Linker Conjugates 45

Others Others
cIAP1 Ligand-Linker Conjugates 9 feature an IAP ligand specifically targeting the E3 ubiquitin ligase, along with a PROTAC linker. It is valuable tools for developing SNIPERs[1].

化合物

BRD4 ligand-Linker Conjugate 1
Cat.No: T39629
Synonym: BRD4 ligand-Linker Conjugate 1
Target:
Zanamivir-Cholesterol Conjugate
Cat.No: T40140
Synonym:
Target:
Coumarin-Quinone Conjugate
Cat.No: T37797
Synonym:
Target:
Wortmannin-Rapamycin Conjugate
Cat.No: T36314
Synonym:
Target:
NMI 8739
Cat.No: T11079
Synonym: n-docosahexaenoyl dopamine,Dha-DA conjugate
Target: Dopamine Receptor
Phalloidin-Tetramethylrhodamine Conjugate
Cat.No: T36853
Synonym:
Target:
Phalloidin-AMCA Conjugate
Cat.No: T36852
Synonym:
Target:
Bilirubin Conjugate (sodium salt)
Cat.No: T35980
Synonym:
Target:
AZD 1775 Linker Conjugate 1 TFA
Cat.No: T77496L
Synonym: AZD 1775 Linker Conjugate 1 TFA( 2101954-45-2 Free base)
Target:
FAK ligand-Linker Conjugate 1
Cat.No: T17943
Synonym:
Target: Others
K-Ras ligand-Linker Conjugate 1
Cat.No: T18054
Synonym:
Target: Others
K-Ras ligand-Linker Conjugate 6
Cat.No: T18059
Synonym:
Target: Others
K-Ras ligand-Linker Conjugate 5
Cat.No: T18058
Synonym:
Target: Others
K-Ras ligand-Linker Conjugate 3
Cat.No: T18056
Synonym:
Target: Others
K-Ras ligand-Linker Conjugate 2
Cat.No: T18055
Synonym:
Target: Others
K-Ras ligand-Linker Conjugate 4
Cat.No: T18057
Synonym:
Target: Others
DBCO-Biotin
Cat.No: T17742
Synonym: Azadibenzocyclooctyne-Biotin conjugate
Target:
Lenalidomide-acetylene-C5-COOH
Cat.No: T18063
Synonym: Cereblon ligand-linker Conjugate
Target: Others
ATRA-biotin
Cat.No: T39703
Synonym: ATRA-biotin,Biotin-ATRA-conjugate
Target:
Taurolithocholic acid
Cat.No: T34788
Synonym: Lithocholyltaurine,Lithocholic acid taurine conjugate
Target:
MC-Val-Cit-PAB-VX765
Cat.No: T33243
Synonym: Belnacasan-conjugate,VX765-conjugate,MC-Val-Cit-PABC-VX765
Target:
XMT-1519 conjugate-1
Cat.No: T77861
Synonym:
Target:
Dacomitinib metabolite M2
Cat.No: T23950
Synonym: Dacomitinib cysteine conjugate,UNII-SOA52D3NLL
Target:
DOX−NOP1 HCl
Cat.No: T27200
Synonym: doxorubicin-NOP1 conjugate,doxorubicin-NOP1 HCl,DOX−NOP1 Hydrochloride
Target:
Zn-DPA-maytansinoid conjugate 1
Cat.No: T74975
Synonym:
Target:
MitoE10
Cat.No: T33406
Synonym: Mito E10,Vitaman E-triphenylphosphonium conjugate,MitoE-10
Target:
Anti-α-Tubulin Antibody, AF555 conjugate
Cat.No: T75383
Synonym:
Target:
ALC-0159
Cat.No: T9520
Synonym:
Target: Others
Auristatin F
Cat.No: T14349
Synonym:
Target: Microtubule Associated
1V209
Cat.No: T8316
Synonym: TLR7 agonist T7
Target: TLR
Paclitaxel-SMCC
Cat.No: T28289
Synonym: SMCC taxol, Taxol-SMCC, Taxol SMCC,Paclitaxel with SMCC linker,SMCC-Taxol,Paclitaxel ADC conjugate.
Target:
Tauro-Obeticholic Acid sodium
Cat.No: T83858
Synonym: Tauro-6-Ethylchenodeoxycholic Acid,Tauro-6-Ethyl-CDCA,Obeticholic Acid Taurine Conjugate,Tauro-OCA,T-ECDCA
Target:
DM1-SMe
Cat.No: T21408
Synonym: DM1-SSMe
Target: Microtubule Associated
NH-bis(C1-Boc)
Cat.No: T18479
Synonym: 亚氨基二乙酸二异丁酯
Target: Others
LY3325656
Cat.No: T70005
Synonym:
Target:
CCK2R Ligand-Linker Conjugates 1
Cat.No: T17727
Synonym:
Target: Others
cIAP1 Ligand-Linker Conjugates 16
Cat.No: T39609
Synonym: cIAP1 Ligand-Linker Conjugates 16
Target:
Cereblon Ligand -Linker Conjugates 2 TFA
Cat.No: T7757
Synonym:
Target:
cIAP1 Ligand-Linker Conjugates 15 hydrochloride
Cat.No: T17886
Synonym: E3 ligase Ligand-Linker Conjugates 34 hydrochloride
Target: Others
cIAP1 Ligand-Linker Conjugates 3
Cat.No: T17894
Synonym: E3 ligase Ligand-Linker Conjugates 40
Target: Others
Conjugated Estrogen sodium
Cat.No: T19988
Synonym: Conjugated estrogens,Conest,HSDB 3076,Kestrin,Estrogens, conjugated,TAG-39
Target:
GalNAc unconjugated/naked Inclisiran
Cat.No: T74876
Synonym:
Target:
9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)
Cat.No: T35854
Synonym:
Target:
VHL Ligand-Linker Conjugates 17
Cat.No: T18873
Synonym:
Target: Others
cIAP1 Ligand-Linker Conjugates 1
Cat.No: T17895
Synonym: E3 ligase Ligand-Linker Conjugates 41
Target: Others
AhR Ligand-Linker Conjugates 1
Cat.No: T17364
Synonym: E3 Ligase Ligand-Linker Conjugates 57
Target: Others
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride
Cat.No: T17884
Synonym: E3 ligase Ligand-Linker Conjugates 33 Hydrochloride
Target: Others
cIAP1 Ligand-Linker Conjugates 7
Cat.No: T17898
Synonym: E3 ligase Ligand-Linker Conjugates 44
Target: Others
Conjugated linoleic acid
Cat.No: T21009
Synonym:
Target:
cIAP1 Ligand-Linker Conjugates 9
Cat.No: T17899
Synonym: E3 ligase Ligand-Linker Conjugates 45
Target: Others
Cat. No. Product Name Target Signaling Pathways
T31964 Glycolithocholic acid

Lithocholic acid glycine conjugate,甘氨石胆酸,Lithocholylglycine

Others Others
Glycolithocholic acid (Lithocholic acid glycine conjugate) 属于内源性代谢产物,是甘氨酸结合的次级胆汁酸。它可用于诊断非酒精性脂肪性肝炎,溃疡性结肠炎和原发性硬化性胆管炎。
T83673 4-Hydroxyphenylpropionylglycine

Phloretylglycine,4-hydroxy PPG,Phloretic Acid Glycine Conjugate

4-Hydroxyphenylpropionylglycine是一种由条件必需氨基酸酪氨酸代谢形成的代谢产物。通过芳香族氨基酸转氨酶、酪氨酸转氨酶以及肠道微生物作用后,结合甘氨酸共轭生成。此外,4-Hydroxyphenylpropionylglycine也是酚类化合物phloretin的代谢产物。
T4820 Maleimide

马来酰亚胺,2,5-Pyrroledione

Others Others
Maleimide (2,5-Pyrroledione) 可用于制备荧光探针,主要用于硫醇分析物的特异性检测。它也可用于制备用于癌症研究的抗体-药物偶联物 (ADC)。
TN2362 Sudan I

苏丹红Ⅰ,苏丹红一号,Solvent Yellow 14

Others; Antibacterial Microbiology/Virology; Others
Sudan I (Solvent Yellow 14) 是一种偶氮共轭红色染料,抑制产气荚膜梭菌和鼠李糖菌的生长,可用于一些产品的添加剂,如油、溶剂或抛光剂。
T73772 Estrone sulfate potassium

Endogenous Metabolite Metabolism
Estrone sulfate potassium 是一种雌激素酯和共轭物,是一种天然内源性类固醇。
T10815 Cinnamoylglycine

Endogenous Metabolite Metabolism
Cinnamoylglycine 是肉桂酸和的甘氨酸结合物,是人体尿液代谢物。它被用作的尿液标志物,能够作为在抗生素研究期之后定殖耐药性的标志物。
T5259 Glycochenodeoxycholic acid sodium salt

GCDCA,甘氨鹅脱氧胆酸钠,Sodium glycochenodeoxycholate

Apoptosis; Others; Endogenous Metabolite Apoptosis; Metabolism; Others
Glycochenodeoxycholic acid sodium salt (GCDCA) 是一种从脱氧鹅胆酸和甘氨酸在肝脏中形成的胆汁盐,可诱导肝细胞凋亡。它起到洗涤剂的作用,可溶解脂肪吸收,并本身被吸收。
T4588 Glycochenodeoxycholic Acid

甘氨鹅脱氧胆酸,Glycine chenodeoxycholate,Chenodeoxycholylglycine,GCDCA,Glycochenodeoxycholate,Lithocholylglycine

Apoptosis; Endogenous Metabolite Apoptosis; Metabolism
Glycochenodeoxycholic Acid (Lithocholylglycine) 是一种从脱氧鹅胆酸和甘氨酸在肝脏中形成的胆汁盐,可诱导肝细胞凋亡。它有洗涤剂的作用,可溶解脂肪吸收,并本身被吸收。
T5234 Glycoursodeoxycholic acid

Ursodeoxycholylglycine,甘氨熊胆酸,GUDCA

Others; Endogenous Metabolite Metabolism; Others
Glycoursodeoxycholic acid (Ursodeoxycholylglycine) 是一种酰基甘氨酸和胆汁酸-甘氨酸缀合物,是熊去氧胆酸的代谢物。
T26288 Clovamide

trans-Clovamide,N-trans-Caffeoy-L-dopa

Apoptosis; Influenza Virus; ROS; Antibacterial Apoptosis; Immunology/Inflammation; Microbiology/Virology
Clovamide (trans-Clovamide) 是一种天然存在的咖啡酰结合物,具有抗菌、抗炎、抗氧化和神经保护作用。它是一种极好的活性氧和氧自由基清除剂。
T75319 Taurodeoxycholic acid

Taurodeoxychloic acid

Apoptosis; Calcium Channel; Caspase Apoptosis; Membrane transporter/Ion channel; Metabolism; Proteases/Proteasome
Taurodeoxycholic acid (Taurodeoxychloic acid) 是脱氧胆酸的胆汁酸牛磺酸共轭物,是一种人体代谢物,可稳定线粒体膜,减少自由基形成。Taurodeoxycholic acid 通过阻断钙介导的凋亡通路以及 Caspase-12 激活来抑制凋亡 (apoptosis)。Taurodeoxycholic acid具有神经保护活性,可用于研究 3-硝基丙酸诱导或稳定遗传的亨廷顿舞蹈病 (HD) 。
T37520 DL-Glutamic acid

DL-Glutamic acid, the conjugate acid of Glutamic acid, serves as a crucial metabolite. In comparison to the α and β polymorphs of L-Glutamic acid's second phase, DL-Glutamic acid exhibits enhanced stability[1].
T39562 γ-Amanitin

γ-Amanitin an ADC cytotoxin and isolated from the mushroom. γ-Amanitin inhibits RNA polymerase II and disrupts synthesis of mRNA. γ-Amanitin shows similar effects to α-Amanitin and β-Amanitin.
T39605 β-D-Glucopyranosyl abscisate

ABA-GE,β-D-Glucopyranosyl abscisate,(S)-cis,trans-Abscisicacidglucosylester

β-D-Glucopyranosyl abscisate (ABA-GE) is a hydrolyzable conjugate of abscisic acid (ABA), which predominantly accumulates in the vacuole and likely in the endoplasmic reticulum. The deconjugation of β-D-Glucopyranosyl abscisate enables a swift release of free ABA in response to abiotic stress factors like dehydration and salt stress. β-D-Glucopyranosyl abscisate plays a crucial role in maintaining ABA homeostasis.
T73915 Luisol A

Luisol A 是一种芳香族四醇,是链霉菌属的河口海洋放线菌的主要代谢产物。Luisol A 是一种蒽醌抗生素类似物,是 ADC 细胞毒素 (ADC Cytotoxin)。

天然产物

Glycolithocholic acid
Cat.No: T31964
Synonym: Lithocholic acid glycine conjugate,甘氨石胆酸,Lithocholylglycine
Target: Others
4-Hydroxyphenylpropionylglycine
Cat.No: T83673
Synonym: Phloretylglycine,4-hydroxy PPG,Phloretic Acid Glycine Conjugate
Target:
Maleimide
Cat.No: T4820
Synonym: 马来酰亚胺,2,5-Pyrroledione
Target: Others
Sudan I
Cat.No: TN2362
Synonym: 苏丹红Ⅰ,苏丹红一号,Solvent Yellow 14
Target: Others, Antibacterial
Estrone sulfate potassium
Cat.No: T73772
Synonym:
Target: Endogenous Metabolite
Cinnamoylglycine
Cat.No: T10815
Synonym:
Target: Endogenous Metabolite
Glycochenodeoxycholic acid sodium salt
Cat.No: T5259
Synonym: GCDCA,甘氨鹅脱氧胆酸钠,Sodium glycochenodeoxycholate
Target: Apoptosis, Others, Endogenous Metabolite
Glycochenodeoxycholic Acid
Cat.No: T4588
Synonym: 甘氨鹅脱氧胆酸,Glycine chenodeoxycholate,Chenodeoxycholylglycine,GCDCA,Glycochenodeoxycholate,Lithocholylglycine
Target: Apoptosis, Endogenous Metabolite
Glycoursodeoxycholic acid
Cat.No: T5234
Synonym: Ursodeoxycholylglycine,甘氨熊胆酸,GUDCA
Target: Others, Endogenous Metabolite
Clovamide
Cat.No: T26288
Synonym: trans-Clovamide,N-trans-Caffeoy-L-dopa
Target: Apoptosis, Influenza Virus, ROS, Antibacterial
Taurodeoxycholic acid
Cat.No: T75319
Synonym: Taurodeoxychloic acid
Target: Apoptosis, Calcium Channel, Caspase
DL-Glutamic acid
Cat.No: T37520
Synonym:
Target:
γ-Amanitin
Cat.No: T39562
Synonym:
Target:
β-D-Glucopyranosyl abscisate
Cat.No: T39605
Synonym: ABA-GE,β-D-Glucopyranosyl abscisate,(S)-cis,trans-Abscisicacidglucosylester
Target:
Luisol A
Cat.No: T73915
Synonym:
Target:
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