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15

抑制剂 & 化合物

1

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T0899	Dehydroacetic acid 脱氢乙酸,Methylacetopyronone,Biocide 470F	Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Dehydroacetic acid (Methylacetopyronone) 是一种吡喃衍生物，具有植物毒性作用，可作抗菌和抗真菌剂。
T22269	Benzyldodecyldimethylammonium Chloride Dihydrate	Antibacterial	Microbiology/Virology
	Benzyldodecyldimethylammonium chloride dihydrate 可以用作杀虫试剂，可以靶向耐药性细菌，如耐甲氧西林金黄色葡萄球菌、耐多药铜绿假单胞菌等，且具有浓度依赖性。
T19774	Methylisothiazolinone KB-838,MI,N-Methylisothiazolin-3-one,甲基异噻唑啉酮,Methylisothiazolinone free base	Antibacterial	Microbiology/Virology
	Methylisothiazolinone (MI) 是合成的杀菌剂和防腐剂，可广泛用于工业和消费产品。它作为化妆品和盥洗用品中的防腐剂。
T0037	Halazone 哈拉宗,Cloritines,Pantocid,Halazon	Sodium Channel; Antibacterial; Antibiotic; Carbonic Anhydrase	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Halazone (Pantocid) 是一种非典型的磺酰胺衍生物，有抗菌活性。它也是碳酸酐酶 II 抑制剂，Kd 值为 1.45 µM。它广泛用于饮用水消毒，可保护钠通道免于灭活。
T0669	Chloramine-T Chloralone,氯胺 T,Chlorasan,Chlorozone	Others; Antibacterial	Microbiology/Virology; Others
	Chloramine-T (Chloralone) 是一种 N-氯化和 N-去质子化磺胺，用作杀生物剂和温和消毒剂。
T0336	Benzalkonium chloride 苯扎氯铵,Alkyldimethylbenzylammonium chloride	Others; Antibacterial	Microbiology/Virology; Others
	Benzalkonium chloride (Alkyldimethylbenzylammonium chloride) 是一种含有季铵基团的阳离子表面活性剂，也是一种抗菌剂，在滴眼液中用作防腐剂。
T28029	Methylisothiazolinone hydrochloride N-Methylisothiazolin-3-one,MI,2-甲基-4-异噻唑啉-3-酮盐酸盐,KB-838,Methylisothiazolinone HCl
	Methylisothiazolinone is a powerful synthetic biocide and preservative.
T20857	Polixetonium chloride
	Polixetonium chloride is a cooling tower biocide.
T25347	Dodine Karpen,Syllit 65,Melprex 65,Cyprex,ENT 16,436
	Dodine is a fungicide used to control scab on apples, pears, and pecans, brown rot of peaches, and several foliar diseases of peaches, strawberries, cherries, sycamore trees, and black walnuts. It is also used as an industrial biocide and preservative.
T20427	Dichloramine-T NSC 1130,NSC1130,NSC-1130
	Tosylchloramide sodium salt is a N-chlorinated and N-deprotonated sulfonamide used as a biocide and a mild disinfectant.
T36507	Tetrachlorohydroquinone
	Tetrachlorohydroquinone (TCHQ) is a metabolite of the organochlorine biocide pentachlorophenol. It is cytotoxic to RTL-W1 rainbow trout liver cells (EC50 = 1.55 μM in a neutral red assay). TCHQ increases production of reactive oxygen species (ROS), inhibits apoptosis, and induces loss of the mitochondrial membrane potential and necrosis in splenocytes. In vivo, TCHQ induces glutathione (GSH) depletion in mouse liver.
T19587	Tosylchloramide sodium trihydrate	Others	Others
	Tosylchloramide sodium trihydrate is an agent of disinfectant. It is also used as a biocide in air fresheners and deodorants.
T25628	Lapyrium Lapyrium cation
	Lapyrium is a cationic surfactant that is used in personal care products as a biocide and antistatic. It is also used by the chloride salt, lapyrium chloride, in waste-water treatment and corrosion inhibition formulations.
T40899	2-Chloroacetamide
	2-Chloroacetamide is a versatile chemical compound with several applications. Acting as a preservative and herbicide, it effectively controls vegetation in upland areas as well as paddy fields. Additionally, it serves as a biocide in diverse sectors including agriculture, glues, paints, and coatings. Notably, 2-Chloroacetamide demonstrates inhibitory properties toward very-long-chain fatty acid elongase, further highlighting its multifaceted nature.
T37963	Methylchloroisothiazolinone/Methylisothiazolinone Mixture
	Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) is a mixture of isothiazolinone-derived biocides.1,2It is effective against Gram-positive and Gram-negative bacteria with MIC values of 0.0002, 0.0002, 0.00005, and 0.00005% (w/w) forS. aureus,P. aeruginosa,A. niger, andC. albicans, respectively.2MCIT/MIT can elicit contact sensitization.3Formulations containing MCIT/MIT have been used for controlling microbial growth in industrial and household products. 1.Frenzel, E., Schmidt...

化合物

Dehydroacetic acid

Cat.No: T0899

Synonym: 脱氢乙酸,Methylacetopyronone,Biocide 470F

Target: Antibacterial, Antibiotic, Antifungal

Benzyldodecyldimethylammonium Chloride Dihydrate

Cat.No: T22269

Target: Antibacterial

Methylisothiazolinone

Cat.No: T19774

Synonym: KB-838,MI,N-Methylisothiazolin-3-one,甲基异噻唑啉酮,Methylisothiazolinone free base

Target: Antibacterial

Cat.No: T0037

Synonym: 哈拉宗,Cloritines,Pantocid,Halazon

Target: Sodium Channel, Antibacterial, Antibiotic, Carbonic Anhydrase

Cat.No: T0669

Synonym: Chloralone,氯胺 T,Chlorasan,Chlorozone

Target: Others, Antibacterial

Benzalkonium chloride

Cat.No: T0336

Synonym: 苯扎氯铵,Alkyldimethylbenzylammonium chloride

Target: Others, Antibacterial

Methylisothiazolinone hydrochloride

Cat.No: T28029

Synonym: N-Methylisothiazolin-3-one,MI,2-甲基-4-异噻唑啉-3-酮盐酸盐,KB-838,Methylisothiazolinone HCl

Polixetonium chloride

Cat.No: T20857

Cat.No: T25347

Synonym: Karpen,Syllit 65,Melprex 65,Cyprex,ENT 16,436

Cat.No: T20427

Synonym: NSC 1130,NSC1130,NSC-1130

Tetrachlorohydroquinone

Cat.No: T36507

Tosylchloramide sodium trihydrate

Cat.No: T19587

Target: Others

Cat.No: T25628

Synonym: Lapyrium cation

2-Chloroacetamide

Cat.No: T40899

Methylchloroisothiazolinone/Methylisothiazolinone Mixture

Cat.No: T37963

Cat. No.	Product Name	Target	Signaling Pathways
T5779	MOSLOFLAVONE	IL Receptor; Virus Protease; TNF; Antibacterial	Apoptosis; Immunology/Inflammation; Microbiology/Virology
	Mosloflavone 从Scutellaria baicalensis Georgi 中分离出的类黄酮，具有抗EV71活性。它可抑制铜绿假单胞菌的毒力和生物膜形成，有作为杀菌剂的潜力。它在病毒感染的初始阶段抑制 VP2 病毒复制和蛋白质表达，并抑制病毒 VP2 衣壳蛋白合成。

天然产物

Cat.No: T5779

Target: IL Receptor, Virus Protease, TNF, Antibacterial

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