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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T22371	Mivacurium dichloride 米库氯铵,Mivacurium chloride,二氯美维库铵	AChR	Neuroscience
	Mivacurium dichloride (Mivacurium chloride) 是苄基异喹啉衍生物，可与 nAChR 偶联，以减少或抑制乙酰胆碱对肌肉细胞末端盘的去极化作用。它也是非去极化短效的神经肌肉阻滞剂和骨骼肌松弛剂。
T31914	Gantacurium chloride GW 280430A,AV4430A,AV 4430A,GW280430,GW 280430,GW-0430
	Gantacurium chloride is a benzylisoquinoline alkaloid, which may be used as an adjuvant in anesthesia.
T33879	Papaveraldine Xanthaline
	Papaveraldine is a benzylisoquinoline alkaloid that papaverine degradation product.
T38132	(S)-Higenamine hydrobromide
	(S)-Higenamine hydrobromide, an S-enantiomer of Higenamine, serves as the preliminary compound in benzylisoquinoline alkaloid biosynthesis. It is formed through the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) via norcoclaurine synthase (NCS)[1].
T79966	AChE/BChE-IN-14
	AChE/BChE-IN-14（compound 13）是一种从多花菜根分离提取的苯基异喹啉生物碱。该化合物对乙酰胆碱酯酶（AChE）和丁酰胆碱酯酶（BChE）展现了抑制效应，并具备抗氧化性能，可作为阿尔茨海默病研究的实验材料。
T69139	Thalicarpine
	Thalicarpine is a natural aporphine benzylisoquinoline vinca alkaloid with antineoplastic activity. Thalicarpine binds to and inhibits p-glycoprotein, the multidrug resistance efflux pump. Thalicarpine also induces single-strand breaks in DNA and arrests cancer cells at the G2/M and G1 phase of the cell cycle. Check for active clinical trials or closed clinical trials using this agent.
T75641	(S)-Higenamine
	(S)-Higenamine ((S)-Norcoclaurine)，一种苄基异喹啉生物碱，作为其生物合成路径中的起始化合物，通过去甲月桂碱合酶(NCS)催化多巴胺与4-羟基苯乙醛(4-HPAA)的缩合反应形成。

化合物

Mivacurium dichloride

Cat.No: T22371

Synonym: 米库氯铵,Mivacurium chloride,二氯美维库铵

Target: AChR

Gantacurium chloride

Cat.No: T31914

Synonym: GW 280430A,AV4430A,AV 4430A,GW280430,GW 280430,GW-0430

Target:

Papaveraldine

Cat.No: T33879

Synonym: Xanthaline

Target:

(S)-Higenamine hydrobromide

Cat. No.	Product Name	Target	Signaling Pathways
T3429	Protopine 原阿片碱,Macleyine,Hypercorine,Corydinine,Biflorine,Fumarine	Reactive Oxygen Species; Platelet aggregation; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB; Others
	Protopine (Fumarine) 是一种常存在于亚洲东北部的一些植物中的异喹啉类生物碱，常用于抗肿瘤、抗炎活性的研究。
T0461L	Berberine sulfate AI3-61947,Berberin sulfate,Berberine sulphate,Berberal
	Berberine sulfate (Berberal) 是苄基异喹啉生物碱原小檗碱类的季铵盐，可用于研究2型糖尿病、腹部肥胖和代谢相关脂肪性肝病。
T2996	Tetrandrine NSC-77037,d-Tetrandrine,Hanfangchin A,粉防己碱,Fanchinine,Sinomenine A,汉防己甲素	Potassium Channel; Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Tetrandrine (Sinomenine A) 是来自粉防己的一种双苯基异喹啉生物碱，可抑制电压门控钙离子通道 (ICa) 和 Ca2+激活的钾离子通道。