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Search Results for " antitumoral "

12

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T7747	Datelliptium chloride hydrochloride	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Datelliptium chloride hydrochloride 是一种衍生自玫瑰树碱的 DNA 嵌入剂，具有抗肿瘤活性。
T3691	(Rac)-SAR131675 SAR131675	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	(Rac)-SAR131675 是一种有效的、选择性的VEGFR3抑制剂，其IC50=23 nM。
T9864	Debio-0123 WEE1-IN-5	Wee1	Cell Cycle/Checkpoint
	Debio-0123 (WEE1-IN-5) 是一种口服有效且高度特异性的WEE1抑制剂，IC50值在低纳摩尔范围内。Debio-0123 抑制磷酸化 CDC2。Debio-0123 可增强卡铂在体内的抗肿瘤活性，而这两种药物单独使用都没有活性。
T11542	HDAC-IN-4	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor (pIC50s: 7.2 and 6.8 in BRET assay) with antitumoral activity.
T39889	Antitumor agent-23
	Antitumor agent-23 exhibits potent antitumoral activity, as demonstrated by its GI50 values of 38, 48, 5, 27, 80, and 28 nM against the lymphoma cell lines GRANTA-519, KARPAS-422, KARPAS-299, RAMOS, DAUDI, and RAJI respectively.
T21096	Decamethylene glycol alpha,omega-Decanediol,Decamethylenediol,1,10-Dihydroxydecane,Decane-1,10-diol
	Decamethylene glycol is a substance used as a reagent in the biological study of modified oligonucleotide with in vivo antitumoral activity. Also used in the pharmaceutical study on the composition of essential oils obtained from myrrh and frankincense an
T11930	M8891	Others	Others
	M8891 is an orally active, reversible and brain penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor(IC50 :54nM;Ki:4.33 nM).M8891 inhibits growth of primary endothelial cells as well as tumor cells and demonstrates antiangiogenic and antitumoral acti
T83142	Alloferon 2
	Alloferon 2，一种来自双翅目昆虫Calliphora vicina血液的抗病毒及抗肿瘤肽。
T72551	Antitumor agent-87
	Antitumor agent-87为一种有效抗肿瘤化合物，对CYP1A1具有高亲和性（Ki值0.23 µM），表现出抗增殖活性并能诱导细胞周期在G2/M期停滞，进而展现抗肿瘤活性。
T75500	Batzelladine D
	Batzelladine D (Compound 1) 是一种 Pdr5p 转运蛋白催化活性和功能活性的抑制剂。Batzelladine D 抑制 Pdr5p ATPase 活性，IC50值为 7.1 µM。Batzelladine D 具有抗真菌 (antifungal)、抗寄生虫 (antiparasitic)、抗病毒 (antiviral)、抗细菌 (antibacterial) 和抗肿瘤活性。
T76162	Stem bromelain
	茎型菠萝蛋白酶(EC 3.4.22.32)，主要自(Ananas comosus)茎中提取的半胱氨酸类蛋白酶，展现广泛纤溶、抗水肿、抗血栓及抗炎活性。此外，具备抗肿瘤、抗白血病及抗转移效能。
T83143	Alloferon 1
	Alloferon 1 是一种具有抗病毒和抗肿瘤功能的肽。它能激活人外周血淋巴细胞的天然细胞毒性，诱导IFN合成，并在小鼠体内增强其抗病毒和抗肿瘤的防御机制。此外，Alloferon 1 在 λ-角叉菜胶诱导的足水肿模型中展现出抗炎作用。它可从双翅目昆虫丽蝇Calliphora vicina的血液中提取。

化合物

Datelliptium chloride hydrochloride

Cat.No: T7747

Target: DNA/RNA Synthesis

(Rac)-SAR131675

Cat.No: T3691

Synonym: SAR131675

Target: VEGFR

Cat.No: T9864

Synonym: WEE1-IN-5

Target: Wee1

Cat.No: T11542

Target: HDAC

Antitumor agent-23

Cat.No: T39889

Decamethylene glycol

Cat.No: T21096

Synonym: alpha,omega-Decanediol,Decamethylenediol,1,10-Dihydroxydecane,Decane-1,10-diol

Cat.No: T11930

Target: Others

Cat.No: T83142

Antitumor agent-87

Cat.No: T72551

Cat.No: T75500

Cat.No: T76162

Cat.No: T83143

Cat. No.	Product Name	Target	Signaling Pathways
T26810	Bikaverin BRN 0358013,Lycopersin
	Bikaverin is a reddish pigment produced by different fungal species with antibiotic properties against certain protozoa and fungi. Bikaverin also has antitumoral activity against different cancer cell lines.
T72645	Norbatzelladine L
	Norbatzelladine L 是一种 Pdr5p 转运蛋白催化活性和功能活性的抑制剂。Norbatzelladine L 抑制 Pdr5p ATPase 活性，IC50值为 3.8 µM。Norbatzelladine L 具有抗真菌 (antifungal)、抗寄生虫 (antiparasitic)、抗病毒 (antiviral)、抗细菌 (antibacterial) 和抗肿瘤活性。

天然产物

Cat.No: T26810

Synonym: BRN 0358013,Lycopersin

Norbatzelladine L

Cat.No: T72645

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