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Cat. No. | Product Name | Target | Signaling Pathways |
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TP1108 |
Allergen Gal d 4 (46-61), chicken
Lysozyme C (46-61) (chicken) |
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Allergen Gal d 4 (46-61), chicken is a hen egg white lysozyme peptide. | |||
T22596 |
BADGE
|
PPAR | DNA Damage/DNA Repair; Metabolism |
BADGE 是一种标准化的化学过敏原。它的生理作用是通过增加组胺释放和细胞介导的免疫来实现的。 | |||
T14377 |
AZD5423
|
Glucocorticoid Receptor | Endocrinology/Hormones |
AZD5423 是可吸入的非甾体糖皮质激素受体选择性调节剂,能够有效降改善轻度过敏性哮喘患者的过敏原诱导反应。 | |||
T68173 |
ZD-2138
Ici-D2138 |
Lipoxygenase | Metabolism |
ZD-2138是一种有效且具有选择性的5-脂氧合酶(5-LOX)的特异性抑制剂,抑制了过敏原诱导的肺支气管收缩,可减少豚鼠孤立气道的神经诱发性快速激肽能收缩。ZD-2138可用来治疗哮喘疾病。 | |||
T81805 |
Mevonlerbart
|
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Mevlonlerbart是针对Felcat allergen 1的特异性IgG4κ类抗体。Felcat allergen 1为一过敏原蛋白。 | |||
T82371 |
Freneslerbart
|
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Freneslerbart为针对Felcat allergen 1的IgG4κ类抗体,后者为一过敏原蛋白。 | |||
T70107 |
Olcorolimus
|
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Olcorolimus inhibits single allergen-induced allergic inflammation such as eosinophilic and lymphocytic infiltration and mRNA expression for interleukin (IL)-4 and IL-5 | |||
T81561 |
Palmitoyl tripeptide-8
|
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Palmitoyl tripeptide-8,一种生物活性肽,具抗敏感功能,常作为化妆品成分应用。 | |||
T11482 | GSK2245035 | Others | Others |
GSK2245035 is a highly selective intranasal TLR7 agonist with preferential Type-1 interferon (IFN)-stimulating properties (pEC50s: 9.3 and 6.5 for IFNα and TFNα). It effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood | |||
T82820 |
Bremzalerbart
|
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Bremzalerbart为针对主要桦树花粉过敏原Bet v 1-A的BETVIA的人源IgG4单克隆抗体。 | |||
T82946 |
Atisnolerbart
|
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Atisnolerbart为一种靶向BETVIA的人源IgG4抗体,其中BETVIA指的是桦树花粉过敏原Bet v 1-A的主要成分。 | |||
T35457 |
(±)12(13)-DiHOME
(±)12(13)-DiHOME,Isoleukotoxin diol |
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(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME , a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin. [1] It is formed from 12(13)-EpOME by soluble epoxide hydrolase (sEH) in neutrophils. [2] 12(13)-DiHOME is toxic to Sf21 cells expressing sEH and to lacZ-expressing control cells, unlike isoleukotoxin, which is only toxic to cells containing sEH.[1] [2] Levels of 12(13)-DiHOME are increased in rat spinal cord following burn injury, and it enhances cold tolerance... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4S0398 |
Rosin
松香树脂 |
p38 MAPK | MAPK |
Rosin 分离自松木或松树桩中,是一种频繁接触的过敏原,能够导致过敏性接触性皮炎。 | |||
T0834 |
Ethylparaben
Ethyl 4-hydroxybenzoate,Ethyl parahydroxybenzoate,羟苯乙酯,尼泊金乙酯 |
Antibacterial; Antifungal | Microbiology/Virology |
Ethylparaben (Ethyl parahydroxybenzoate) 是一种标准化的化学过敏原。 对羟基苯甲酸乙酯的生理作用是通过增加组胺释放和细胞介导免疫来实现的。 | |||
T0927 |
Butylparaben
Butyl 4-hydroxybenzoate,Butyl parahydroxybenzoate,尼泊金丁酯,对羟基苯甲酸丁酯 |
Endogenous Metabolite; Antibacterial; Antibiotic | Metabolism; Microbiology/Virology |
Butylparaben (Butyl 4-hydroxybenzoate) 是一种标准化的化学过敏原,可增加组胺释放和细胞介导的免疫。 | |||
T1297 |
Eugenol
丁香酚,4-Allylguaiacol,Allylguaiacol,4-Allyl-2-methoxyphenol,Eugenic acid |
Apoptosis; Ferroptosis; Reactive Oxygen Species; Antibacterial; Parasite | Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB |
Eugenol (Allylguaiacol) 是一种从丁香中发现的精油,抑制脂质的过氧化,具有抗菌,驱虫和抗氧化活性。 | |||
T0908 |
Chlorquinaldol
5,7-Dichloro-8-hydroxy-2-methylquinoline,Chloquinan,氯喹那多 |
Antibacterial; Antibiotic; Antifungal | Microbiology/Virology |
Chlorquinaldol (5,7-Dichloro-8-hydroxy-2-methylquinoline) 是一种抗菌剂, 有潜力研究局部皮肤病症和阴道感染。 | |||
T5320 |
Tulipalin A
α-methylene-γ-butyrolactone,2-Methylenebutyrolactone,2-甲烯基丁内酯 |
Others; Drug Metabolite | Metabolism; Others |
Tulipalin A (α-methylene-γ-butyrolactone) 是来源于郁金香鳞茎的有毒糖苷。Tulipalin A 是引起过敏性接触皮炎的致敏性致敏物 (causative allergen),在低剂量影响免疫细胞的功能,例如 Jurkat T 细胞。 |