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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T15260 |
Evenamide
NW-3509 |
Sodium Channel | Membrane transporter/Ion channel |
Evenamide (NW-3509) 是一种口服有效的电压门控钠通道 (sodium channel, VGSC) 阻滞剂,Ki 为 0.4 µM,在精神分裂症中有研究价值。Evenamide 在精神病,躁狂症,抑郁和攻击性的各种啮齿动物模型中具有显著功效。 | |||
T60390 |
PI-55
6-(2-hydroxy-3-methylbenzylamino)purine |
Others | Others |
PI-55 (6-(2-hydroxy-3-methylbenzylamino)purine) is a cytokinin receptor inhibitor that exhibits structural similarity to 6-benzylaminopurine (BAP). It competitively inhibits BAP binding on the specific Arabidopsis receptors CRE1/AHK4 and AHK3. Furthermore, PI-55 effectively suppresses cytokinins-induced haustorium formation and enhances parasite aggressiveness [1]. | |||
T3655 |
BMS-1
PD1-PDL1 inhibitor 1,PD-1/PD-L1 inhibitor 1 |
Apoptosis; PD-1/PD-L1 | Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation |
BMS-1 (PD-1/PD-L1 inhibitor 1)是一种 PD-1/PD-L1蛋白质/蛋白质相互作用的抑制剂,IC50为 6 到 100 nM。 | |||
T78186 |
Ac-VLPE-FMK
Ac-Val-Leu-Pro-Glu(OMe)-CH2F |
||
Ac-VLPE-FMK为一种四肽基单氟甲基酮(m-FMK),兼作Cat-B及Cat-L抑制剂,适用于癌症侵袭性研究。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1032 |
Geissoschizine methyl ether
缝籽木嗪甲醚,缝籽嗪甲醚 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Geissoschizine methyl ether 是从钩藤中发现的一种生物碱,是 Yokukansan 的主要活性成分,具有精神药物作用。它是一种有效的 5-羟色胺 A 受体激动剂,是 Yokukansan 改善攻击性和社交性的候选药物。 |