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Search Results for " yohimbine "

7

抑制剂 & 化合物

11

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T124173	18-Beta-hydroxy-3-epi-alpha-yohimbine
	18-Beta-hydroxy-3-epi-alpha-yohimbine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124173。
T39161	Ro60-0175 Ro60-0175	5-HT Receptor	GPCR/G Protein; Neuroscience
	Ro60-0175 是 5- 羟色胺 2B (5-HT2B) 和 5- 羟色胺 2C (5-HT2C) 血清素受体亚型的选择性激动剂，常用富马酸盐形式。它具有 5- 羟色胺 2B 受体激动剂和 5- 羟色胺 2C 受体激动剂的作用。
T29305	1-Methylyohimbine
	1-Methylyohimbine is a biochemical.
T29286	10-Hydroxyyohimbine
	10-Hydroxyyohimbine is a biochemical.
T34178	Pseudoyohimbine hydrochloride
	Pseudoyohimbine hydrochloride is a biochemical.
T70975	Carsatrin succinate
	Carsatrin succinate is the salt form of Carsatin, a purinylpiperazine derivative used as a cardiotonic and antiarrhythmic. Carsatrin acts as positive inotropic agent that increases twitch tension and prolongs the action potential (AP) duration of ventricular muscle without affecting the Na+, K+-ATPase, adenylyl cyclase, phosphodiesterase isozymes, or cardiac myofilaments. Carsatrin’s positive inotropic effect can be prevented by tetrodotoxin but not by the adrenergic antagonists timolol, yohimbi...
T71122	Carsatrin (free base)
	Carsatrin is purinylpiperazine derivative. as cardiotonic and antiarrhythmic. Carsatrin acts as positive inotropic agent that increases twitch tension and prolongs the action potential (AP) duration of ventricular muscle without affecting the Na+, K+-ATPase, adenylyl cyclase, phosphodiesterase isozymes, or cardiac myofilaments. Carsatrin’s positive inotropic effect can be prevented by tetrodotoxin but not by the adrenergic antagonists timolol, yohimbine, or prazosin

化合物

18-Beta-hydroxy-3-epi-alpha-yohimbine

Cat.No: T124173

Cat.No: T39161

Synonym: Ro60-0175

Target: 5-HT Receptor

1-Methylyohimbine

Cat.No: T29305

10-Hydroxyyohimbine

Cat.No: T29286

Pseudoyohimbine hydrochloride

Cat.No: T34178

Carsatrin succinate

Cat.No: T70975

Carsatrin (free base)

Cat.No: T71122

Cat. No.	Product Name	Target	Signaling Pathways
TCS2185	Yohimbine	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Yohimbine 是一种有效的、相对非选择性的α2 - 肾上腺素能受体拮抗剂，IC50=0.6μM。
T2142	Yohimbine hydrochloride 盐酸育亨宾,Antagonil,Yohimbine HCl	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Yohimbine hydrochloride (Antagonil) 是一种植物生物碱，具有 α-2-肾上腺素能阻断活性。它被用作散瞳药和治疗勃起功能障碍。
T8044	Ajmalicine 阿吗里新,Lamuran,Delta-Yohimbine,Raubasine,Ajmalicin	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Ajmalicine (Raubasine) 是一种有效的抗肾上腺素 (adrenolytic) 剂，优先阻断 α1-肾上腺素受体 (α1-adrenoceptor)。Ajmalicine 是一种可逆性但非竞争性尼古丁受体 (nicotine receptor) 完全抑制剂，IC50 为 72.3 μM。Ajmalicine 还可用于降压、蛇毒，具有镇静活性。
TN3393	alpha-Yohimbine	5-HT Receptor	GPCR/G Protein; Neuroscience
	Alpha-Yohimbine is a 5-HT1A receptor agonist, it is strong selective 2-adrenoceptor antagonist. Alpha-Yohimbine possess aphrodisiac effect.
TN3507	beta-Yohimbine	Adrenergic Receptor; Antifection	GPCR/G Protein; Microbiology/Virology; Neuroscience
	Beta-Yohimbine has approximately twice as toxic as yohimbine and corynanthine about one fifth as toxic. Beta-yohimbine has alpha-1 and alpha-2 adrenoceptor blocking activities, it has cardiovascular effects. Beta-Yohimbine has anti-plasmodial and anti-mal
T29884	allo-Yohimbine
	allo-Yohimbine is a biochemical.
T4429	Rauwolscine hydrochloride Corynanthidine hydrochloride,盐酸育亨宾碱,萝芙素盐酸盐,α-Yohimbine hydrochloride,Isoyohimbine hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Rauwolscine hydrochloride (Isoyohimbine hydrochloride) 是一种高选择性的 α2 adrenergic 受体拮抗剂，Ki=12 nM。
T83436	18β-Hydroxy-3-epi-α-yohimbine
	18β-Hydroxy-3-epi-α-yohimbine为育亨宾衍生物，该天然产物主要存在于Rauvolfia vomitoria中。
T30969	Clitocine	Apoptosis; BCL	Apoptosis
	Clitocine 是一种来从蘑菇中提取的一种腺苷类似物，是一种有效的转录通读剂，是一种无义突变的抑制剂，具有抗癌活性，可诱导携带 p53 无义突变等位基因的细胞产生 p53 蛋白。Clitocine 通过促进 Mcl-1 降解来增强 TRAIL 介导的人结肠癌细胞凋亡。
T78468	Yohimbic acid hydrate
	Yohimbic acid hydrate，一种Yohimbine的两性脱甲基衍生物，具有血管舒张效果，且在骨关节炎（OA）研究中展现出潜在应用价值。
T33342L	Methyl reserpate NSC81464,NSC 81464,NSC-81464,Me reserpate	Norepinephrine	Neuroscience
	Methyl reserpate (NSC 81464) 是一种从 Rauwolfia vomitoria 的根和叶中提取出来的育亨宾 (Yohimbine) 型生物碱，抑制去甲肾上腺素转运到嗜铬囊泡中。

天然产物

Cat.No: TCS2185

Target: Adrenergic Receptor

Yohimbine hydrochloride

Cat.No: T2142

Synonym: 盐酸育亨宾,Antagonil,Yohimbine HCl

Target: Adrenergic Receptor

Cat.No: T8044

Synonym: 阿吗里新,Lamuran,Delta-Yohimbine,Raubasine,Ajmalicin

Target: Adrenergic Receptor

alpha-Yohimbine

Cat.No: TN3393

Target: 5-HT Receptor

beta-Yohimbine

Cat.No: TN3507

Target: Adrenergic Receptor, Antifection

allo-Yohimbine

Cat.No: T29884

Rauwolscine hydrochloride

Cat.No: T4429

Synonym: Corynanthidine hydrochloride,盐酸育亨宾碱,萝芙素盐酸盐,α-Yohimbine hydrochloride,Isoyohimbine hydrochloride

Target: Adrenergic Receptor

18β-Hydroxy-3-epi-α-yohimbine

Cat.No: T83436

Cat.No: T30969

Target: Apoptosis, BCL

Yohimbic acid hydrate

Cat.No: T78468

Methyl reserpate

Cat.No: T33342L

Synonym: NSC81464,NSC 81464,NSC-81464,Me reserpate

Target: Norepinephrine

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