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16

抑制剂 & 化合物

13

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T29867	ALK-001 C-20D3vitamin A,C-20-D3-Retinyl Acetate,ALK 001,ALK001,C-20-D3-vitamin A
	ALK-001 is a vitamin A analog, which may be used to treat Stargardt disease.
T19389	L-Ascorbic acid 2-phosphate magnesium 2-Phospho-L-ascorbic acid magnesium,维生素C磷酸酯镁,维生素 C 磷酸酯镁	Phosphatase; Phosphorylase	Metabolism
	L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) 是长效的维生素 C 衍生物，能够以刺激胶原蛋白的表达和形成。它提高成骨细胞分化过程中 hASC 中的碱性磷酸酶特性和 runx2A 的表达。它能够以作为培养基补充人脂肪干细胞的成骨分化。
T8856	Ascorbyl Propyl Hyaluronate	Others	Others
	Ascorbyl Propyl Hyaluronate 是透明质酸和维生素 C 的完美结合，克服了维生素 C 的不稳定性，是改善皱纹、滋润、镇静肌肤、美白的优质原料。
T0752	Ascorbyl palmitate L-抗坏血酸棕榈酸酯,L-Ascorbic acid 6-hexadecanoate,6-O-Palmitoyl-L-ascorbic acid,L-Ascorbyl 6-palmitate,抗坏血酸棕榈酸酯	Reactive Oxygen Species; Endogenous Metabolite	Immunology/Inflammation; Metabolism; NF-κB
	Ascorbyl palmitate (L-Ascorbic acid 6-hexadecanoate) 是由抗坏血酸和棕榈酸形成的一种酯，一种脂溶性形式的维生素 C。
T22352	L-Gulose	Others; Endogenous Metabolite	Metabolism; Others
	L-Gulose 是一种合成维生素 C 的生物中间体，是一种 L-sorbosone 的呋喃糖形式，是L 己糖。
T26168	Rufigallol AI3 00865,AI3-00865,AI300865
	Rufigallol (AI3-00865) 是一种具有六个羟基的电子缺失的盘状分子，是诱导非平面AIE 分子形成DLC 的良好单元，是一种蒽醌衍生物。Rufigallol 诱导获得了DLC 特性，而TPE 基团的引入使分子结构在聚集状态下具有良好的荧光。Rufigallol 在体外的显著的协同抗疟作用，在体内与维生素C 和酮类化合物一起使用具有协同作用并显示出抗疟活性。
T20174	Tetrahexyldecyl ascorbate BV-OSC,Oristar THA,Nikkol BV-OSC
	Tetrahexyldecyl ascorbate is one of vitamin C.
T13961	Vitamin CK3 维生素CK3	Others	Others
	Vitamin CK3 is the combination of Vitamin C and vitamin K3 and has been shown to inhibit tumor growth and lung metastasis.
T35500	3-epi-25-hydroxy Vitamin D3 3-epi-25-hydroxy Vitamin D3
	3-epi-25-hydroxy Vitamin D3is the C-3 epimer of 25-hydroxy vitamin D3.1Dietary administration of 3-epi-25-hydroxy vitamin D3(0.5 and 1 IU/g) decreases levels of serum parathyroid hormone (PTH) in male, but not female, weanling rats. 1.Djekic-Ivankovic, M., Lavery, P., Agellon, S., et al.The C-3α epimer of 25-hydroxycholecalciferol from endogenous and exogenous sources supports normal growth and bone mineral density in weanling ratsJ. Nutr.147(2)141-151(2017)
TP1628	Activated Protein C (390-404), human
	Activated Protein C (390-404), human, a peptide derived from the vitamin K-dependent serine protease, effectively suppresses the anticoagulant activity of APC[1].
T11645	Impurity C of Calcitriol	Others	Others
	Impurity C of Calcitriol是 Calcitriol 的杂质。Impurity C of Calcitriol 可用于合成维生素D3。
T12722	Ribocil-C Racemate	Others	Others
	Ribocil-C Racemate 是 Ribocil-C 的外消旋体。Ribocil-C 是具有高度选择性的，细菌核黄素核糖开关 (bacterial riboflavin riboswitches) 抑制剂。
TP2190	vitamin D binding protein precrusor (208-218) [Homo sapiens]/[Oryctolagus cuniculus]	Others	Others
	Vitamin D-binding protein is a multifunctional, highly expressed, polymorphic serum protein. These range from the transport of vitamin D metabolites to possible roles in the immune system and host defense. The molecular weight range, the time course of ap
T19390	L-Ascorbic acid 2-phosphate 维生素C磷酸酯,2-Phospho-L-ascorbic acid	Others	Others
	L-ascorbic acid 2-phosphate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation. L-ascorbic acid 2-phosphate is a long-acting vitamin C derivative that can stimulate collagen formation and expression.
T76101	Ascorbate oxidase
	Ascorbate oxidase（即维生素 C 氧化酶），作为一种氧化还原酶，在细胞外基质中的氧化还原调节中起作用。该酶催化抗坏血酸与氧之间的反应，生成脱氢抗坏血酸。
T35983	Carotenoid Mixture
	Carotenoid mixture is a mixture of carotenoids that contains the antioxidative and anti-inflammatory carotenoid capsanthin and the antioxidative vitamin A precursor β-carotene , as well as additional carotenoids and carotenoid esters.1,2,3,4 1.Kim, J.S., Lee, W.M., Rhee, H.C., et al.Red paprika (Capsicum annuum L.) and its main carotenoids, capsanthin and β-carotene, prevent hydrogen peroxide-induced inhibition of gap-junction intercellular communicationChem. Biol. Interact.254146-155(2016) 2.Na...

化合物

Cat.No: T29867

Synonym: C-20D3vitamin A,C-20-D3-Retinyl Acetate,ALK 001,ALK001,C-20-D3-vitamin A

L-Ascorbic acid 2-phosphate magnesium

Cat.No: T19389

Synonym: 2-Phospho-L-ascorbic acid magnesium,维生素C磷酸酯镁,维生素 C 磷酸酯镁

Target: Phosphatase, Phosphorylase

Ascorbyl Propyl Hyaluronate

Cat.No: T8856

Target: Others

Ascorbyl palmitate

Cat.No: T0752

Synonym: L-抗坏血酸棕榈酸酯,L-Ascorbic acid 6-hexadecanoate,6-O-Palmitoyl-L-ascorbic acid,L-Ascorbyl 6-palmitate,抗坏血酸棕榈酸酯

Target: Reactive Oxygen Species, Endogenous Metabolite

Cat.No: T22352

Target: Others, Endogenous Metabolite

Cat.No: T26168

Synonym: AI3 00865,AI3-00865,AI300865

Tetrahexyldecyl ascorbate

Cat.No: T20174

Synonym: BV-OSC,Oristar THA,Nikkol BV-OSC

Cat.No: T13961

Synonym: 维生素CK3

Target: Others

3-epi-25-hydroxy Vitamin D3

Cat.No: T35500

Synonym: 3-epi-25-hydroxy Vitamin D3

Activated Protein C (390-404), human

Cat.No: TP1628

Impurity C of Calcitriol

Cat.No: T11645

Target: Others

Ribocil-C Racemate

Cat.No: T12722

Target: Others

vitamin D binding protein precrusor (208-218) [Homo sapiens]/[Oryctolagus cuniculus]

Cat.No: TP2190

Target: Others

L-Ascorbic acid 2-phosphate

Cat.No: T19390

Synonym: 维生素C磷酸酯,2-Phospho-L-ascorbic acid

Target: Others

Ascorbate oxidase

Cat.No: T76101

Carotenoid Mixture

Cat.No: T35983

Cat. No.	Product Name	Target	Signaling Pathways
T6674	L-Ascorbic acid sodium salt (+)-Sodium L-ascorbate,Vitamin C sodium salt,Sodium ascorbate,L-Ascorbic acid sodium,抗坏血酸钠,Sodium L-ascorbate,维生素C钠	Apoptosis; Others; Calcium Channel; Reactive Oxygen Species; Endogenous Metabolite	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; NF-κB; Others
	L-Ascorbic acid sodium salt (Vitamin C sodium salt) 是一种电子供体，是一种内源性抗氧化剂。它还是一种胶原沉积促进剂和弹性生成抑制剂。它选择性抑制 Cav3.2 通道(Cav3.2 channels)，IC50为 6.5 μM。
T0928	L-Ascorbic acid 维生素C,Vitamin C,Ascorbic acid,L(+)-Ascorbic acid,抗坏血酸,L-Ascorbate	Apoptosis; Calcium Channel; Reactive Oxygen Species; Endogenous Metabolite	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; NF-κB
	L-Ascorbic acid (Vitamin C) 属于天然产物，是一种强效的还原剂和抗氧化剂。L-Ascorbic acid 具有抗细菌感染、解毒反应和胶原蛋白形成的作用。L-Ascorbic acid 被用于治疗坏血病。
T2185	L-Ascorbic acid 2-phosphate trisodium L-抗坏血酸-2-磷酸三钠盐（维生素C）,L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate,L-抗坏血酸-2-磷酸三钠盐	Reactive Oxygen Species; c-Met/HGFR; Endogenous Metabolite	Immunology/Inflammation; Metabolism; NF-κB; Tyrosine Kinase/Adaptors
	L-Ascorbic acid 2-phosphate trisodium (Sodium ascorbyl phosphate) 是长效的维生素 C 衍生物，能够刺激胶原蛋白的表达和形成。Sodium L-ascorbyl-2-phosphate 提高成骨细胞分化过程中 hASC 中的碱性磷酸酶活性和 runx2A 的表达，因此，能够促进人脂肪干细胞的成骨分化。
T2336	Vitamin K2 Menatetrenone,四烯甲萘醌	Endogenous Metabolite	Metabolism
	Vitamin K2 (Menatetrenone) 是内源性代谢产物的一种。
T5578	L-Gulono-1,4-lactone	Others; Endogenous Metabolite	Metabolism; Others
	L-Gulono-1,4-lactone 是一种 L-古洛糖酸-γ-内酯氧化还原酶的作用底物，该酶能促进维生素 C 合成的末步。它是动物、植物和一些原生生物中维生素 C 的直接前体。
T7966	3-O-Ethyl-L-ascorbic acid	Tyrosinase	Proteases/Proteasome
	3-O-Ethyl-L-ascorbic acid 是一种具有增白能力的化妆品酪氨酸酶 (tyrosinase) 抑制剂，是一种稳定的维生素 C 衍生物。它还具有抗氧化能力。
TCO2745	Cyclic AMP Adenosine 3',5'-cyclophosphate,cAMP,腺苷环磷酸酯,环磷腺苷,Cyclic 3',5'-monophosphate adenosine,3',5'-AMP,Adenosine Cyclophosphate	Others; Endogenous Metabolite	Metabolism; Others
	Cyclic AMP (cAMP)(Adenosine 3',5'-cyclophosphate) 是有丝分裂信使，可以促进 G1期到 S 期的细胞周期进程。
T4719	1,4-D-Gulonolactone D-Gulonic acid γ-lactone,D-(-)-古洛糖酸-1,4-内酯	Others; Endogenous Metabolite	Metabolism; Others
	1,4-D-Gulonolactone (D-Gulonic acid γ-lactone) (也称为还原性抗坏血酸，RAA) 是 L-gulono-1,4-lactone oxidoreductase (EC 1.1.3.8)的底物，催化植物和动物中l -抗坏血酸(维生素C)生物合成的最后一步。enzyme L-Gulono-1,4-lactone oxidase 在容易患坏血病、缺乏维生素c的动物(如人类)中缺失。1,4-D-Gulonolactone 存在于人体血液中，并被用作比较运动引起的氧化应激变化的标志物之一。
T14291	Anisindione	Others	Others
	Anisindione 是合成的抗凝血剂，对活性促凝因子II，VII，IX 和X 的形成具有抑制作用。
T10077	2-O-β-D-Glucopyranosyl-L-ascorbic acid AA-2βG,抗坏血酸葡糖苷	Others	Others
	2-O-β-D-Glucopyranosyl-L-ascorbic acid (AA-2βG) is isolated from Lycium Fruit. It is a stable vitamin C analog with anti-tumor activity.
T4917	Dehydroascorbic acid (L)-Dehydroascorbic acid,脱氢抗坏血酸,去氢抗坏血酸	Endogenous Metabolite	Metabolism
	Dehydroascorbic acid ((L)-Dehydroascorbic acid) 是维生素 C 的氧化型，能够透过血脑屏障，对中风具有有效的脑保护作用。
TN3056	4-O-Galloylbergenin	Others	Others
	4-O-Galloylbergenin shows significant 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging activity with EC50 7.8 uM, it shows more antioxidant activity than the positive control vitamin C (EC50 = 28.3 uM).
TN4004	Erythro-Guaiacylglycerol β-dihydroconiferyl ether
	Erythro-Guaiacylglycerol β-dihydroconiferyl ether 是从加拿大枫糖浆中提取的，具有潜在的抗氧化活性，可用于研究营养保健品。

天然产物

L-Ascorbic acid sodium salt

Cat.No: T6674

Synonym: (+)-Sodium L-ascorbate,Vitamin C sodium salt,Sodium ascorbate,L-Ascorbic acid sodium,抗坏血酸钠,Sodium L-ascorbate,维生素C钠

Target: Apoptosis, Others, Calcium Channel, Reactive Oxygen Species, Endogenous Metabolite

L-Ascorbic acid

Cat.No: T0928

Synonym: 维生素C,Vitamin C,Ascorbic acid,L(+)-Ascorbic acid,抗坏血酸,L-Ascorbate

Target: Apoptosis, Calcium Channel, Reactive Oxygen Species, Endogenous Metabolite

L-Ascorbic acid 2-phosphate trisodium

Cat.No: T2185

Synonym: L-抗坏血酸-2-磷酸三钠盐（维生素C）,L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate,L-抗坏血酸-2-磷酸三钠盐

Target: Reactive Oxygen Species, c-Met/HGFR, Endogenous Metabolite

Cat.No: T2336

Synonym: Menatetrenone,四烯甲萘醌

Target: Endogenous Metabolite

L-Gulono-1,4-lactone

Cat.No: T5578

Target: Others, Endogenous Metabolite

3-O-Ethyl-L-ascorbic acid

Cat.No: T7966

Target: Tyrosinase

Cat.No: TCO2745

Synonym: Adenosine 3',5'-cyclophosphate,cAMP,腺苷环磷酸酯,环磷腺苷,Cyclic 3',5'-monophosphate adenosine,3',5'-AMP,Adenosine Cyclophosphate

Target: Others, Endogenous Metabolite

1,4-D-Gulonolactone

Cat.No: T4719

Synonym: D-Gulonic acid γ-lactone,D-(-)-古洛糖酸-1,4-内酯

Target: Others, Endogenous Metabolite

Cat.No: T14291

Target: Others

2-O-β-D-Glucopyranosyl-L-ascorbic acid

Cat.No: T10077

Synonym: AA-2βG,抗坏血酸葡糖苷

Target: Others

Dehydroascorbic acid

Cat.No: T4917

Synonym: (L)-Dehydroascorbic acid,脱氢抗坏血酸,去氢抗坏血酸

Target: Endogenous Metabolite

4-O-Galloylbergenin

Cat.No: TN3056

Target: Others

Erythro-Guaiacylglycerol β-dihydroconiferyl ether

Cat.No: TN4004

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