首页工具

登录

搜索结果

Search Results for " tyrosinase-in-2 "

5

抑制剂 & 化合物

9

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T60278	Tyrosinase-IN-2	Tyrosinase	Proteases/Proteasome
	Tyrosinase-IN-2 (compound 67) 是一种有效的酪氨酸酶抑制剂。酪氨酸酶是一种含铜金属酶，负责黑色素生物合成和酶促褐变中的限速催化步骤。Tyrosinase-IN-2 具有研究皮肤美白剂和食品防腐剂的潜力。
T75714	Decapeptide-12
	Decapeptide-12，一个小型寡肽，作为tyrosinase的抑制剂，通过与tyrosinase的C末端残基相互作用(Kd: 61.1 μM)发挥作用。作为mushroom tyrosinase的竞争性抑制剂(IC50: 40 µM)，Decapeptide-12有效上调SIRT的转录水平，并能减少黑色素细胞中的黑色素含量，适用于黑色素生成、衰老和炎症的研究。
T61780	MtTMPK-IN-4
	MtTMPK-IN-4 (compound 2), a para-piperidine, is a highly potent inhibitor of thymidylate kinase (MtTMPK) in Mycobacterium tuberculosis, exhibiting an IC50 value of 6.1 μM. Additionally, it possesses remarkable inhibitory activity against tyrosinase. Furthermore, MtTMPK-IN-4 exhibits potent antibacterial properties [1] [2].
T76347	Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
	Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2 是一种促黑素激素，能够激活黑素细胞。该化合物具有促进酪氨酸酶活性的功能，并在大鼠模型中显示出调节体温的效果。
T37832	CAY10761 CAY10761
	CAY10761 is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; IC50s = 467 and 429 μM for the human and snake venom enzymes, respectively).1,2 It also inhibits mushroom tyrosinase (Ki = 1.9 μM) and urease from jack bean, P. mirabilis, and B. pasteurii (IC50s = 0.093, <0.125, and 0.089 mM, respectively, at pH 8.2).3,4 \|1. Khan, K.M., Fatima, N., Rasheed, M., et al. 1,3,4-Oxadiazole-2(3H)-thione and its analogues: A new class of non-competitive nucleotide pyrophosphatases/p...

化合物

Tyrosinase-IN-2

Cat.No: T60278

Target: Tyrosinase

Cat.No: T75714

Cat.No: T61780

Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2

Cat.No: T76347

Cat.No: T37832

Synonym: CAY10761

Cat. No.	Product Name	Target	Signaling Pathways
TCS2170	2,5-Dihydroxyacetophenone Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,2 '，5'-二羟基苯乙酮,Acetylhydroquinone,2,5-二羟基苯乙酮,DHAP	ERK; NF-κB; Tyrosinase	MAPK; NF-κB; Proteases/Proteasome
	2,5-Dihydroxyacetophenone (Quinacetophenone) 是从熟地黄中分离出的一种天然产物，通过阻断 ERK1/2和 NF-κB 信号通路，抑制活化巨噬细胞中炎症介质的产生。
T3S0645	N-trans-Feruloyltyramine Feruloyltyramine,N-Feruloyltyramine,Moupinamide,N-反式阿魏酰酪胺	Others; COX	Immunology/Inflammation; Neuroscience; Others
	N-trans-Feruloyltyramine (Feruloyltyramine) 是从大麻中分离得到的一种生物碱，是COX1和COX2的抑制剂，具有抗氧化和抗炎活性。
T5980	2-Ketoglutaric acid α-酮戊二酸,alpha-酮戊二酸	Tyrosinase; Endogenous Metabolite	Metabolism; Proteases/Proteasome
	2-Ketoglutaric acid 是 Krebs 循环的中间体，可以产生 ATP 或 GTP 。2-Ketoglutaric acid 还充当氮同化反应的主要碳骨架。2-Ketoglutaric acid 是酪氨酸酶(tyrosinase)的可逆抑制剂 (IC50=15 mM)。
T4S0998	Trifolirhizin 红车轴草根甙/三叶豆紫檀苷,三叶豆紫檀苷	TNF; Tyrosinase	Apoptosis; Proteases/Proteasome
	Trifolirhizin 是一种从苦参根中分离出的 pterocarpan 黄酮类化合物。它具有酪氨酸酶高抑制活性，IC50=506 μM。它具有抗炎和抗癌的潜能。
T3923	Calycosin Cyclosin,3'-Hydroxyformononetin,异黄酮,毛异黄酮	Apoptosis; Tyrosinase	Apoptosis; Proteases/Proteasome
	Calycosin (Cyclosin) 是一抗氧化和抗炎症活性天然产物。
T3737	3-(2,4-Dihydroxyphenyl)propanoic acid 3-(2,4-二羟基苯)丙酸,Hydroumbellic acid,2,4-Dihydroxyhydrocinnamic acid	Tyrosinase	Proteases/Proteasome
	3-(2,4-Dihydroxyphenyl)propanoic acid (Hydroumbellic acid) 是竞争性酪氨酸酶 (tyrosinase) 抑制剂，可抑制 L-Tyrosine 和 DL-DOPA，IC50和 Ki 分别为 3.02 μM 和 11.5 μM。
TMA0003	Trans-caffeic acid	cAMP; Tyrosinase	GPCR/G Protein; Proteases/Proteasome
	Trans-caffeic acid stearyl ester is posited to inhibit melanogenesis signaling while suppressing cAMP levels and, subsequently, MC1R, MITF, tyrosinase, TRP-2 and TRP-1 down-regulation, resulting in the suppression of tyrosinase activity, DOPA oxidase activity and melanin synthesis.
T10664	Calcium 2-oxoglutarate	Others; Tyrosinase	Others; Proteases/Proteasome
	Calcium 2-oxoglutarate is an intermediate in the production of GTP or ATP in the Krebs cycle. It is a reversible inhibitor of tyrosinase (IC50: 15 mM).
T2S0799	Noroxyhydrastinine	Tyrosinase	Proteases/Proteasome
	Noroxyhydrastinine exhibits potent melanogenesis-inhibitory activities, it inhibits melanogenesis, at least in part, by inhibiting the expression of protein levels of tyrosinase, TRP-1, and TRP-2 in α-MSH-stimulated B16 melanoma cells.

天然产物

2,5-Dihydroxyacetophenone

Cat.No: TCS2170

Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,2 '，5'-二羟基苯乙酮,Acetylhydroquinone,2,5-二羟基苯乙酮,DHAP

Target: ERK, NF-κB, Tyrosinase

N-trans-Feruloyltyramine

Cat.No: T3S0645

Synonym: Feruloyltyramine,N-Feruloyltyramine,Moupinamide,N-反式阿魏酰酪胺

Target: Others, COX

2-Ketoglutaric acid

Cat.No: T5980

Synonym: α-酮戊二酸,alpha-酮戊二酸

Target: Tyrosinase, Endogenous Metabolite

Cat.No: T4S0998

Synonym: 红车轴草根甙/三叶豆紫檀苷,三叶豆紫檀苷

Target: TNF, Tyrosinase

Cat.No: T3923

Synonym: Cyclosin,3'-Hydroxyformononetin,异黄酮,毛异黄酮

Target: Apoptosis, Tyrosinase

3-(2,4-Dihydroxyphenyl)propanoic acid

Cat.No: T3737

Synonym: 3-(2,4-二羟基苯)丙酸,Hydroumbellic acid,2,4-Dihydroxyhydrocinnamic acid

Target: Tyrosinase

Trans-caffeic acid

Cat.No: TMA0003

Target: cAMP, Tyrosinase

Calcium 2-oxoglutarate

Cat.No: T10664

Target: Others, Tyrosinase

Noroxyhydrastinine

Cat.No: T2S0799

Target: Tyrosinase

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼