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Cat. No.	Product Name	Target	Signaling Pathways
T7625	TRAP-6 PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA)	Protease-activated Receptor	GPCR/G Protein
	TRAP-6 (Thrombin Receptor Activator Peptide 6) 是一种多肽片段，是选择性的蛋白酶激活受体 1 (PAR1) 激动剂，通过凝血酶受体激活人血小板。
T8958	PU-H54	GPR	Endocrinology/Hormones; GPCR/G Protein
	PU-H54 是一种基于嘌呤的 Grp94 抑制剂。它是一种基于 Grp94 选择性间苯二酚的抑制剂，通过探测 Grp94 中 S2 亚袋的专有结合区而分离。
TP1015	NFAT Inhibitor VIVIT peptide	Others	Others
	NFAT Inhibitor (VIVIT peptide) 是NFAT 的细胞渗透性肽抑制剂，能够选择性抑制钙调磷酸酶介导的NFAT 脱磷酸作用。
T60557	TRAP-6-IN-1
	TRAP-6-IN-1 (Compound 8) 是胶原蛋白和TRAP-6的双重抑制剂，IC50值分别为 17.12 μM 和 11.88 μM。TRAP-6-IN-1 非竞争性抑制激动剂诱导的血小板聚集。
T38852L	TRAP-6 amide acetate	Protease-activated Receptor	GPCR/G Protein
	TRAP-6 amide acetate 是一种 PAR-1 凝血酶受体激动剂肽。
T2114	VER-82576 NVP-BEP800	HSP	Cytoskeletal Signaling; Metabolism
	VER-82576 (NVP-BEP800) 是一种可口服的，选择性的 Hsp90抑制剂，对 Hsp90β 的 IC50值为 58 nM，对 Hsp90 家族成员 Trap-1 和 Grp94 的选择性超过 70 倍。
T38961L	DP-1 hydrochloride DP-1 hydrochloride(1472616-61-7 Free base)	Drug Metabolite	Metabolism
	DP-1 hydrochloride是 SDC-TRAP-0063 的降解产物，是 Ganetespib 的一个片段。Ganetespib 是一种具有抗肿瘤活性的热休克蛋白 90 (HSP90) 抑制剂。
T22739	DMPO 5,5-二甲基-1-吡咯啉-N-氧化物,5,5-Dimethyl-1-pyrroline N-oxide	Others	Others
	DMPO (5,5-Dimethyl-1-pyrroline N-oxide) 是一种细胞渗透性亲水自旋诱捕剂，可用于超氧化物检测。
T3098	Vorapaxar sulfate SCH 530348 sulfate,Zontivity,vorapaxar monosulfate,沃拉帕沙	Protease-activated Receptor	GPCR/G Protein
	Vorapaxar sulfate (Zontivity) 是一种选择性、口服活性和竞争性的凝血酶受体蛋白酶激活受体(PAR-1)拮抗剂，Ki 值为 8.1 nM。它剂量依赖性抑制凝血酶受体激活肽 (TRAP) 诱导的血小板聚集，是抗血小板药物。
T7013	Vorapaxar SCH 530348,MK-5348,沃拉帕沙	Protease-activated Receptor	GPCR/G Protein
	Vorapaxar (MK-5348) 是抗血小板药物，是一种选择性、口服活性和竞争性的凝血酶受体蛋白酶激活受体(PAR-1)拮抗剂，Ki 值为 8.1 nM。它靠剂量依赖性抑制凝血酶受体激活肽 (TRAP) 诱导的血小板聚集。
T38887	TRAP-6 amide TFA
	TRAP-6 amide TFA is a PAR-1 thrombin receptor agonist peptide.
T80111	TRAP-5 amide
	TRAP-5 amide为蛋白酶激活受体1（PAR1）特异性的激动剂肽。
T78037	Hepcidin-1 (mouse) TFA
	Hepcidin-1 (mouse) TFA是调控铁代谢平衡的肽类激素。该化合物通过提高TRAP、组织蛋白酶K及MMP-9的mRNA水平并促进TRAP-5b蛋白的分泌，同时降低FPN1蛋白表达，导致细胞内铁含量上升。此外，Hepcidin-1 (mouse) TFA还有助于破骨细胞的分化。
T78099	iso-TRAP-6 iso-SFLLRN
	iso-TRAP-6(iso-SFLLRN)为PAR-1激动剂，具备激活血小板的能力。该化合物作为TRAP-6的同系物，通过以异丝氨酸替换丝氨酸成为首位氨基酸而构成。
T80108	Hepcidin-1 (mouse)
	Hepcidin-1 (mouse) 是调控铁平衡的内源性多肽激素，通过上调TRAP、组织蛋白酶K和MMP-9的mRNA水平及增强TRAP-5b蛋白的分泌作用。此外，Hepcidin-1 (mouse) 降低FPN1蛋白水平并提升细胞内铁含量，且促进破骨细胞的分化。
T38852	TRAP-6 amide
	TRAP-6 amide is a PAR-1 thrombin receptor agonist peptide.
T35867	TRAP-6 Peptide (trifluoroacetate salt)
	TRAP-6 peptide is a hexapeptide corresponding to residues 42-47 of protease-activated receptor 1 (PAR1). It acts as an agonist of PAR1, inducing platelet aggregation in human platelet-rich plasma ex vivo (EC50 = 0.8 μM). TRAP-6 (0.3 and 0.6 mg/kg) has a triphasic effect on mean arterial blood pressure (MAP) in anesthetized rats with a short decrease, an increase, and then a longer decrease in MAP following intravenous administration.
T36777	Thrombin Receptor Agonist Peptide (trifluoroacetate salt)
	Thrombin receptor agonist peptide (TRAP-14) is a 14-amino acid peptide agonist of the α-thrombin receptor. It induces aggregation of washed platelets as well as platelets in citrated and hirudin plasma. TRAP-14 (100 μM) increases the cytosolic calcium concentration in isolated guinea pig pulmonary smooth muscle cells 5-fold over baseline. It increases pulmonary arterial pressure in isolated guinea pig lung when used at a concentration of 1 μM, which is comparable to the effect induced by 10 nM α...
T38961	DP-1
	DP-1, a Ganetespib degradation product, represents a fragment derived from SDC-TRAP-0063. Ganetespib itself functions as an inhibitor of heat shock protein 90 (HSP90), exhibiting notable anti-tumor properties.
T7496	Thrombin Receptor Activator for Peptide 5 (TRAP-5) Thrombin Receptor Activator for Peptide	Protease-activated Receptor	GPCR/G Protein
	Thrombin Receptor Activator for Peptide 5 (TRAP-5) 也称为凝血因子 II 受体 (1-5) 或蛋白酶激活受体 1 (1-5)，用于研究冠心病 (CHD)。
T81171	SH491
	SH491（Compound 33）是一款抗骨质疏松药物。该化合物能够抑制RANKL诱导的骨髓源性单核细胞（BMM）分化为破骨细胞（IC50: 11.8 nM）。同时，SH491降低了破骨细胞形成的相关标记基因（TRAP、CTSK、MMP-9和ATPase v0d2）以及相应蛋白（TRAP、CTSK、MMP-9）的表达。
T80239	TFLLRNPNDK-NH2	Thrombin	Proteases/Proteasome
	TFLLRNPNDK-NH2 是具备生物活性的肽类化合物，作为凝血酶受体激活肽（PAR-1 激动剂肽）能够可逆地与 PAR-1 结合，模拟凝血酶对底物蛋白通过水解作用产生的“束缚配体”。同凝血酶的作用相似，此肽能够增加液体与蛋白质的渗透性。
T36026	DEPMPO 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide
	DEPMPO is a phosphorylated derivative of the widely used DMPO spin trap. It has been reported to produce spin adducts with increased stability particularly for the adduct of superoxide. [1] [2] [3] DEPMPO displays a detectable spin adduct signal at a concentration as low as 1 mM, as compared to 5 mM for DMPO.[3] A significant advantage of using DEPMPO in trapping superoxide radical is that the decomposition of DEPMPO/O2 - does not produce the OH adduct, which can be a drawback when using DMPO....
T36501	CYPMPO RR 071
	CYPMPO is a free radical spin trap with excellent trapping capabilities toward hydroxyl and superoxide radicals in biological and chemical systems. Decay of the superoxide adduct of CYPMPO proceeds in an apparent first order fashion with half-lives of 15 and 51 minutes in a UV-illuminated hydrogen peroxide solution and a hypoxanthine/xanthine oxidase system, respectively. CYPMPO traps superoxide radicals generated by bovine neutrophils as effectively as DEPMPO.[1] The high melting point (126°C),...
T37857	9(Z)-Pentacosene
	9(Z)-Pentacosene is a cuticular hydrocarbon and insect sex hormone.1,2,3 It is found in the cuticle of female F. canicularis flies and is an attractant to males in a trap assay.1 9(Z)-Pentacosene is a contact sex hormone in scarab beetles and locust borers that is more abundant in females than males.2,3 It elicits arrestment, alignment, and mounting by males of both species in mating assays but only elicits copulation by the locust borer. 9(Z)-Pentacosene is also produced by the orchid O. exalta...
T77145	Recifercept
	Recifercept (TA-46) 是一种溶解性重组FGFR3分子，能够作为诱饵/配体陷阱，降低与突变FGFR3受体结合的成纤维细胞生长因子数量，用于研究软骨发育不全。
T36221	2-chloro Palmitic Acid
	2-chloro Palmitic acid is a monochlorinated form of palmitic acid . It is produced in a myeloperoxidase (MPO) and time-dependent manner in neutrophils stimulated by phorbol 12-myristate 13-acetate . 2-chloro Palmitic acid (10 μM) induces neutrophil extracellular trap (NET) formation (NETosis) in human neutrophils, increasing DNA release from neutrophils, colocalization of MPO with extracellular DNA (ecDNA), and trapping of E. coli. It increases COX-2 protein levels in human coronary artery endot...

化合物

Cat.No: T7625

Synonym: PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA)

Target: Protease-activated Receptor

Cat.No: T8958

Target: GPR

Cat.No: TP1015

Synonym: VIVIT peptide

Target: Others

Cat.No: T60557

TRAP-6 amide acetate

Cat.No: T38852L

Target: Protease-activated Receptor

Cat.No: T2114

Synonym: NVP-BEP800

Target: HSP

DP-1 hydrochloride

Cat.No: T38961L

Synonym: DP-1 hydrochloride(1472616-61-7 Free base)

Target: Drug Metabolite

Cat.No: T22739

Synonym: 5,5-二甲基-1-吡咯啉-N-氧化物,5,5-Dimethyl-1-pyrroline N-oxide

Target: Others

Vorapaxar sulfate

Cat.No: T3098

Synonym: SCH 530348 sulfate,Zontivity,vorapaxar monosulfate,沃拉帕沙

Target: Protease-activated Receptor

Cat.No: T7013

Synonym: SCH 530348,MK-5348,沃拉帕沙

Target: Protease-activated Receptor

TRAP-6 amide TFA

Cat.No: T38887

Cat.No: T80111

Hepcidin-1 (mouse) TFA

Cat.No: T78037

Cat.No: T78099

Synonym: iso-SFLLRN

Hepcidin-1 (mouse)

Cat.No: T80108

Cat.No: T38852

TRAP-6 Peptide (trifluoroacetate salt)

Cat.No: T35867

Thrombin Receptor Agonist Peptide (trifluoroacetate salt)

Cat.No: T36777

Cat.No: T38961

Thrombin Receptor Activator for Peptide 5 (TRAP-5)

Cat.No: T7496

Synonym: Thrombin Receptor Activator for Peptide

Target: Protease-activated Receptor

Cat.No: T81171

Cat.No: T80239

Target: Thrombin

Cat.No: T36026

Synonym: 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide

Cat.No: T36501

Synonym: RR 071

9(Z)-Pentacosene

Cat.No: T37857

Cat.No: T77145

2-chloro Palmitic Acid

Cat.No: T36221

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