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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T13115 Telomerase-IN-2

Telomerase inhibitor 2,端粒酶抑制剂2

Telomerase DNA Damage/DNA Repair
Telomerase-IN-2 (Telomerase inhibitor 2) 是一种端粒酶抑制剂,通过降低角化不良蛋白的表达来抑制其活性,IC50值为 0.89 µM,具有抗癌作用。
T61679 Abacavir monosulfate

Abacavir monosulfate is an orally active, competitive nucleoside reverse transcriptase inhibitor that effectively inhibits HIV replication. Additionally, it exhibits anticancer properties in prostate cancer cell lines, and has the ability to penetrate the blood-brain-barrier and suppress telomerase activity [1] [2] [3].
T35428 β-Rubromycin

β-Rubromycin is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities.1 It inhibits the growth of HMO2, KATO-III, and MCF-7 cells with GI50 values of 0.5, 0.84, and <0.1 μM, respectively. β-rubromycin inhibits HIV-1 reverse transcriptase activity by 39.7% when used at a concentration of 10 μM. It also has antibacterial activity against Gram-positive bacteria. The structure of β-rubromycin was originally described as containing an ortho-quinone group,...

化合物

Telomerase-IN-2
Cat.No: T13115
Synonym: Telomerase inhibitor 2,端粒酶抑制剂2
Target: Telomerase
Abacavir monosulfate
Cat.No: T61679
Synonym:
Target:
β-Rubromycin
Cat.No: T35428
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T2988 (-)-Epigallocatechin Gallate

Epigallocatechol Gallate,(-)-表没食子儿茶素没食子酸酯,EGCG

Ferroptosis; Reactive Oxygen Species; HIV Protease; Mitochondrial Metabolism; Endogenous Metabolite; Autophagy Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
(-)-Epigallocatechin Gallate (EGCG) 是茶类黄酮,具有强大的抗氧化,抗炎和抗癌作用。它可抑制EGFR 信号传导,有抗癌作用。它是谷氨酸脱氢酶 1/2 抑制剂。它通过激活细胞色素c 氧化酶来诱导氧化磷酸化。

天然产物

(-)-Epigallocatechin Gallate
Cat.No: T2988
Synonym: Epigallocatechol Gallate,(-)-表没食子儿茶素没食子酸酯,EGCG
Target: Ferroptosis, Reactive Oxygen Species, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite, Autophagy
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