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Cat. No.	Product Name	Target	Signaling Pathways
T3988	TOFA MDL14514,RMI14514	Acetyl-CoA Carboxylase	Metabolism
	TOFA (MDL14514) 是有效的乙酰辅酶 A 羧化酶-α (ACCA)的变构抑制剂。
T4669	Fantofarone SR 33557,泛托法隆	Calcium Channel; Parasite	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Fantofarone (SR 33557) 是一种钙离子通道的强效拮抗剂。
T2398	Tofacitinib Citrate CP-690550 citrate,柠檬酸托法替尼,枸橼酸托法替尼,Tasocitinib citrate,Tofacitinib (CP-690550) Citrate	Apoptosis; Influenza Virus; JAK; Antibacterial; Antifungal	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Microbiology/Virology; Stem Cells
	Tofacitinib Citrate (CP-690550 citrate) 是 JAK1/2/3抑制剂，IC50分别为112，20 和 1 nM。它具有抗菌，抗真菌和抗病毒活性。
T6321	Tofacitinib 托法替尼,Tasocitinib,CP-690550	ROCK; Apoptosis; JAK; Src	Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	Tofacitinib (Tasocitinib) 是口服小分子 Janus 激酶抑制剂，用于治疗中度至重度类风湿性关节炎。
T37638	Tofacitinib metabolite-1
	Tofacitinib metabolite-1, a derivative of Tofacitinib, which is a JAK inhibitor, is employed in studies focused on the pharmacokinetics and metabolism of tofacitinib[1][2].
T13427	(3S,4R)-Tofacitinib	Others	Others
	(3S,4R)-Tofacitinib is an less active enantiomer of Tofacitinib. Tofacitinib is a JAK3 inhibitor(IC50 : 1 nM).
T69958	Tofacitinib maleate
	Tofacitinib maleate, also known as tasocitinib, CP-690550, is a Janus kinase (JAK) inhibitor. Tofacitinib maleate modulates the signaling pathway at the point of JAKs, preventing the phosphorylation and activation of STATs. JAK enzymes transmit cytokine signaling through pairing of JAKs (e.g., JAK1/JAK3, JAK1/JAK2, JAK1/TyK2, JAK2/JAK2). Tofacitinib maleate inhibited the in vitro activities of JAK1/JAK2, JAK1/JAK3, and JAK2/JAK2 combinations with IC50 of 406, 56, and 1377 nM, respectively.
T13426	(3R,4S)-Tofacitinib	Others	Others
	(3R,4S)-Tofacitinib is an less active enantiomer of Tofacitinib. Tofacitinib is a JAK3 inhibitor(IC50 : 1 nM).
T72406	Tofacitinib Prodrug-1
	Tofacitinib Prodrug-1 是减轻托法替尼 (Tofacitinib) 全身性不良反应的口服有效前药。Tofacitinib Prodrug-1 能在小鼠模型有效减轻恶唑酮诱导的结肠炎，具有低毒性，是治疗溃疡性结肠炎的潜在候选药物。
T13426L	(3S,4S)-Tofacitinib (3S,4S)-托法替尼	Others	Others
	(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.
T70168	Tofacitinib HCl
	Tofacitinib HCl, also known as tasocitinib, CP-690550, is a Janus kinase (JAK) inhibitor. Tofacitinib HCl modulates the signaling pathway at the point of JAKs, preventing the phosphorylation and activation of STATs. JAK enzymes transmit cytokine signaling through pairing of JAKs (e.g., JAK1/JAK3, JAK1/JAK2, JAK1/TyK2, JAK2/JAK2). Tofacitinib HCl inhibited the in vitro activities of JAK1/JAK2, JAK1/JAK3, and JAK2/JAK2 combinations with IC50 of 406, 56, and 1377 nM, respectively.