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Cat. No. | Product Name | Target | Signaling Pathways |
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T71726 |
TNFalpha-IN-S10
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TNFalpha-IN-S10 is an inhibitor of TNF-α. | |||
T30531L |
BMS-561392 Formic acid
BMS-561392 Formic acid(611227-74-8 Free base) |
MMP | Proteases/Proteasome |
BMS-561392 Formic acid 是 TACE 的选择性抑制剂,可降低 TNFalpha 水平。 | |||
T27967 |
M199
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M199, a novel inhibitor of TLR3/9 activation, induces secretion of IL-6, IL-8 and TNFalpha in human PBMCs. | |||
T70703 |
DK-139
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DK-139 is an inhibitor of NF-kappaB-mediated GROalpha expression, suppressing the TNFalpha-induced invasive capability of MDA-MB-231 human breast cancer cells. | |||
T69831 |
RPR-200765A Mesylayte
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RPR-200765A is a potent and selective inhibitor of p38 MAP kinase (IC50 = 50 nM). It inhibits LPS-stimulated TNFalpha release both in vitro, from human monocytes (EC50 = 110 nM), and in vivo in Balb/c mice (ED50 = 6 mg/kg). At oral doses between 10 and 30 mg/kg/day it reduces the incidence and progression in the rat streptococcal cell wall (SCW) arthritis model when administered in either prophylactic or therapeutic dosing regimens. The compound, which is a mesylate salt and exists as a stable m... |
Cat. No. | Product Name | Target | Signaling Pathways |
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TN1373 |
α-Humulene
Alpha-caryophyllene,ALPHA-律草烯 |
TNF; NOS; COX | Apoptosis; Immunology/Inflammation; Neuroscience |
α-Humulene (Alpha-caryophyllene) 是 Tanacetum vulgareL. 精油的主要成分,显示出抗炎作用,IC50=15±2 μg/mL。它抑制 iNOS 和COX-2表达。 | |||
T8852 |
tubuloside B
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Apoptosis; Others | Apoptosis; Others |
Tubuloside B 是可从管花肉苁蓉茎中分离出的一种天然产物,具有抗氧化活性,可抑制TNFα 诱导的细胞凋亡。 | |||
T4S0350 |
Licochalcone B
甘草查尔酮 B,甘草查尔酮B |
Beta Amyloid; Others | Neuroscience; Others |
Licochalcone B 是从Glycyrrhiza inflate 根中提取的。它能够抑制淀粉样蛋白 β 自聚集作用 (IC50=2.16 μM) ,分解预先形成的 Aβ42原纤维,并通过螯合金属离子抑制金属诱导的 Aβ42聚集。 |
Cat. No. | Product Name | Species | Expression System |
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TMPY-01294 |
TNF alpha Protein, Mouse, Recombinant
TNF-α,Tnfsf1a,TNF-alpha,TNF-a,Tnfa,tumor necrosis factor,TNF... |
Mouse | E. coli |
TNF alpha Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.39 kDa and the accession number is P06804. | |||
TMPY-01697 |
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His)
Tnfr-1,TNFR80,TNF-R-II,TNF-αR2,tumor necrosis factor recepto... |
Mouse | HEK293 Cells |
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is P25119. | |||
TMPY-02535 |
TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc)
TNFalpha-R1,TNFAR,TNF-R-I,TNF-R,TNFRp55,FPF,TNF-R55... |
Mouse | HEK293 Cells |
TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.4 kDa and the accession number is P25118. | |||
TMPK-00583 |
TNF alpha Protein, Ferret, Recombinant (His)
TNF-α,DIF,TNFα,TNF-alpha,TNF α,Cachectin,APC1 protein,TNF,TN... |
Ferret | E. coli |
TNF alpha Protein, Ferret, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 18.88 kDa and the accession number is A3FBF1. | |||
TMPK-00119 |
TNF alpha Protein, Cynomolgus, Recombinant (His)
TNF α,TNFα,APC1 protein,TNF-alpha,TNFA,TNF-α,TNFATNF,TNFSF1A... |
Cynomolgus | HEK293 Cells |
TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 18.35 kDa and the accession number is P79337. | |||
TMPK-00120 |
TNF alpha Protein, Human, Recombinant (His & Avi)
TNFα,APC1 protein,肿瘤坏死因子,TNFSF2,TNF,TNF α,TNF-alpha,TNF-α,TN... |
Human | HEK293 Cells |
TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 20.3 kDa and the accession number is P01375. | |||
TMPK-00121 |
TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated
TNF,TNF-alpha,TNFATNF,DIF,TNFalpha,TNFα,TNFA,TNF-α,... |
Human | HEK293 Cells |
TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 20.3 kDa and the accession number is P01375. | |||
TMPY-05187 |
TNF alpha Protein, Mouse, Recombinant, Biotinylated
Tnfa,TNFSF2,肿瘤坏死因子,Tnfsf1a,TNF-alpha,TNFalpha,DIF,T... |
Mouse | E. coli |
TNF alpha Protein, Mouse, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession number is P06804. | |||
TMPY-01696 |
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (hFc)
TNF-αR2,TNF-R-II,Tnfr2,TNFalpha-R2,TNFBR,tumor necr... |
Mouse | HEK293 Cells |
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.3 kDa and the accession number is P25119. | |||
TMPY-01639 |
TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His)
TNFalpha-R1,TNFRp55,CD120a,TNF-alphaR1,FPF,p55-R,TN... |
Mouse | HEK293 Cells |
TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.8 kDa and the accession number is P25118. | |||
TMPY-01033 |
IL-32 Protein, Human, Recombinant (isoform alpha, His)
IL-32δ,IL-32beta,IL32,TAIFc,IL-32γ,白介素,IL-32 Protein(isoform... |
Human | HEK293 Cells |
IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active,... |