首页工具

登录

搜索结果

Search Results for " sp-α "

14

抑制剂 & 化合物

1

天然产物

3

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T83838	Sp-Thymidine-5'-O-(1-thiotriphosphate) sodium Sp-TTP-α-S
	Sp-Thymidine-5'-O-(1-thiotriphosphate)（Sp-TTP-α-S）是含硫核苷酸衍生物TTP-α-S的一个异构体。它能够结合HIV-1逆转录酶（在镁、锰酸盐和钴存在时，Kds分别为2.88、4.23和20.21 µM）。Sp-TTP-α-S抑制脱氧核苷酸三磷酸三磷酸水解酶SAMHD1（Ki为46 nM）。
T83834	Sp-Guanosine-5'-O-(1-thiotriphosphate) sodium Sp-GTP-α-S,GTPαS(Sp),GTPαS(A)
	Sp-Guanosine-5'-O-(1-thiotriphosphate) (Sp-GTP-α-S) 是一种含硫核苷酸衍生物GTP-α-S的异构体。它能结合到微管蛋白上，在20 mM的浓度下用于无细胞实验时可诱导微管组装。
T83808	Sp-Adenosine-5'-O-(1-thiotriphosphate) sodium Sp-ATP-α-S
	Sp-Adenosine-5'-O-(1-thiotriphosphate) (Sp-ATP-α-S) 是一种含硫核苷酸衍生物 ATP-α-S 的异构体，也是嘌呤P2Y1受体的激动剂。在表达P2Y1受体的HEK293细胞中增加钙离子的流动（对人类受体的EC50 = 9.4 nM）。Sp-ATP-α-S 抑制了ADP诱导的孤立人类血小板聚集（Ki = 4 μM）。它还能引起经卡巴胆碱预收缩的豚鼠十二指肠松弛（EC50 = 426 nM）。
T19889	L-5-BromoTryptophan L-5-溴色氨酸,5-BrW,5 BrW	Others	Others
	L-5-BromoTryptophan (5-BrW) 是色氨酸(Trp) 效应物的类似物，可抑制血红蛋白 S 的凝胶化。
T83831	Sp-2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) sodium Sp-dGTP-α-S
	Sp-2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) 是一种含硫异构体，属于核苷酸三磷酸2'-脱氧鸟苷-5'-O-三磷酸(dGTP)。它通过抑制脱氧核苷酸三磷酸三磷酸水解酶SAMHD1 (Ki = 820 nM)发挥作用。
T83806	Sp-Adenosine-5'-O-(1-thiodiphosphate) sodium Sp-ADP-α-S
	Sp-Adenosine-5’-O-(1-thiodiphosphate) (Sp-ADP-α-S) 是硫含量核苷酸衍生物ADP-α-S的一种异构体。它是磷酸化酶激酶的抑制剂（Ki = 0.53 µM）。Sp-ADP-α-S能引起人类孤立血小板聚集（EC50 = 20 µM），并能使羧胺胆碱预收缩的豚鼠taenia coli松弛（EC50 = 58.9 µM）。
T83823	Sp-Uridine-5'-O-(1-thiotriphosphate) sodium Sp-UTP-α-S
	Sp-Uridine-5'-O-(1-thiotriphosphate) (Sp-UTP-α-S) 是 purinergic Y2 (P2Y2) 和 P2Y4 受体的核苷酸激动剂。它在表达 purinergic P2Y2 或 P2Y4 受体的 1321N1 星形胶质瘤细胞中诱导肌醇磷酸累积（EC50s 分别为 14 和 81 µM）。
T83828	Sp-2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium Sp-dCTP-α-S
	Sp-2'-Deoxycytidine-5'-O-(1-thiotriphosphate) (Sp-dCTP-α-S) 是含硫核苷酸衍生物 dCTP-α-S 的异构体。它抑制解氧核苷酸三磷酸三磷酸水解酶 SAMHD1（Ki = 6.3 µM）。
T26202	SP-Chymostatin B alpha-Mapi
	SP-Chymostatin B is a potent inhibitor of many proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, chymases, and lysosomal cysteine proteinases. It weakly inhibits human leucocyte elastase. It is effective at a final concentra
T24816	SP-100030 SP100030,SP 100030	NF-κB	NF-κB
	SP-100030 是一种有效的 NF-κB 和激活蛋白-1 (AP-1) 双抑制剂 (IC50 分别为 50 和 50 nM)。SP-10003 抑制 Jurkat 和其他T 细胞系产生的 IL-2、IL-8 和 TNF-α 的产生。SP-100030 降低小鼠胶原性关节炎 (CIA)。
T74913	ODN 6016
	ODN 6016 是一种 CpG-A 寡核苷酸。ODN 6016 可诱导IFN-α产生，可用于研究免疫紊乱，包括HIV-1引起的免疫缺陷。ODN 6016 序列：T-sp-C-G-A-C-G-T-C-G-T-G-G-sp-G-sp-G-sp-G。
T75809	2B-(SP) (TFA)
	2B-(SP) TFA 是基于 eIF2B 的糖原合成酶激酶-3 (GSK-3) 底物，可被 GSK-3α 及 GSK-3β 磷酸化。
T83847	SP-A (196-215) (human) TFA Surfactant Protein A,SPA4
	表面活性蛋白A（SP-A）（196-215）是一种合成肽，与人类SP-A的C末端碳水化合物识别域的196至215氨基酸序列相对应。当浓度为1和10 µM时，它能抑制JAWSII鼠树突细胞中由LPS诱导的TNF-α释放。SP-A（196-215）（75 µM）促使JAWSII细胞吞噬P. aeruginosa。通过气管内给药，SP-A（196-215）（50 µg/动物）降低了小鼠P. aeruginosa感染模型的疾病严重程度和肺部形成菌落数。
T36713	Streptochlorin
	Streptochlorin is a bacterial metabolite originally isolated from Streptomyces sp. SF2583 that has diverse biological activities, including antiangiogenic, antiproliferative, and anti-allergic properties. It inhibits TNF-α-induced NF-κB transcriptional activity and decreases proliferation of human umbilical vein endothelial cells (HUVECs) when used at concentrations ranging from 5 to 20 μM. Streptochlorin (12 μg/ml) decreases viability of, as well as induces apoptosis and increases the productio...

化合物

Sp-Thymidine-5'-O-(1-thiotriphosphate) sodium

Cat.No: T83838

Synonym: Sp-TTP-α-S

Sp-Guanosine-5'-O-(1-thiotriphosphate) sodium

Cat.No: T83834

Synonym: Sp-GTP-α-S,GTPαS(Sp),GTPαS(A)

Sp-Adenosine-5'-O-(1-thiotriphosphate) sodium

Cat.No: T83808

Synonym: Sp-ATP-α-S

L-5-BromoTryptophan

Cat.No: T19889

Synonym: L-5-溴色氨酸,5-BrW,5 BrW

Target: Others

Sp-2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) sodium

Cat.No: T83831

Synonym: Sp-dGTP-α-S

Sp-Adenosine-5'-O-(1-thiodiphosphate) sodium

Cat.No: T83806

Synonym: Sp-ADP-α-S

Sp-Uridine-5'-O-(1-thiotriphosphate) sodium

Cat.No: T83823

Synonym: Sp-UTP-α-S

Sp-2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium

Cat.No: T83828

Synonym: Sp-dCTP-α-S

SP-Chymostatin B

Cat.No: T26202

Synonym: alpha-Mapi

Cat.No: T24816

Synonym: SP100030,SP 100030

Target: NF-κB

Cat.No: T74913

Cat.No: T75809

SP-A (196-215) (human) TFA

Cat.No: T83847

Synonym: Surfactant Protein A,SPA4

Cat.No: T36713

Cat. No.	Product Name	Target	Signaling Pathways
TN6735	Bigelovin	Apoptosis; Reactive Oxygen Species; Retinoid Receptor; Autophagy; RAR/RXR	Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; NF-κB
	Bigelovin 是从海百合中分离得到的一种倍半萜内酯，是选择性视黄素 X 受体 α 激动剂。它通过抑制ROS 的生成来调节 mTOR 信号通路。它诱导凋亡和自噬，有抗肿瘤活性。

天然产物

Cat.No: TN6735

Target: Apoptosis, Reactive Oxygen Species, Retinoid Receptor, Autophagy, RAR/RXR

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01569	CD5L Protein, Human, Recombinant (His) PRO229,SP-ALPHA,API6,Spα,CD5 mole...	Human	HEK293 Cells
	CD5L Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.5 kDa and the accession number is O43866.
TMPY-00714	CD5L Protein, Mouse, Recombinant (His) 42010,AAC-11,Sp-alpha,Pdp,Api6,AI047839,CT2,CD5 mol...	Mouse	HEK293 Cells
	CD5L Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is Q9QWK4.
TMPJ-00527	SP-D Protein, Human, Recombinant (His) Lung Surfactant Protein D,SFTP4,COLEC7,SFTPD,PSP-D,...	Human	HEK293 Cells
	Surfactant Pulmonary-Associated Protein D (SP-D) is a 43 kDa member of the collectin family of innate immune modulators. Its principal components consist of a collagen-like region and a C-terminal carbohydrate recognition domain (CRD), a structure that places it in a subset of pattern recognition proteins termed defense collagens. SP-D is constitutively secreted by alveolar lining cells and epithelium associated with tubular structures and induced in cardiac smooth muscle and endothelial cells. ...

重组蛋白

CD5L Protein, Human, Recombinant (His)

Cat.No: TMPY-01569

Species: Human

Expression System: HEK293 Cells

CD5L Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00714

Species: Mouse

Expression System: HEK293 Cells

SP-D Protein, Human, Recombinant (His)

Cat.No: TMPJ-00527

Species: Human

Expression System: HEK293 Cells

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼