首页工具

登录

搜索结果

Search Results for " serm "

21

抑制剂 & 化合物

2

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T10379	Arzoxifene hydrochloride SERM 3,LY 353381 HCl	Others	Others
	Arzoxifene hydrochloride is a selective estrogen receptor modulator that is a potent estrogen antagonist in mammary and uterine tissue.
T2544	Bazedoxifene acetate 醋酸巴多昔芬,WAY-TES 424,TSE 424,WAY-140424	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Bazedoxifene acetate (WAY-TES 424) 是一种非甾体的、有口服活性的、选择性的雌激素受体调节剂，能够作用于 ERα (IC50:26 nM) 和 ERβ (IC50:99 nM) ，可用于研究骨质疏松症。它也是一种IL-6/GP130蛋白相互作用抑制剂，可用于研究胰腺癌。
T6404	Bazedoxifene hydrochloride Bazedoxifene HCl,盐酸巴多昔芬,TSE-424	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Bazedoxifene hydrochloride (TSE-424) 是一种 IL-6/GP130蛋白相互作用抑制剂，可用于胰腺癌的研究。它也是一种有口服活性的，能透过血脑屏障的，非甾体、选择性的雌激素受体调节剂 (SERM)，对 ERα 和 ERβ 作用的 IC50值分别为 26 nM 和 99 nM，可用于研究骨质疏松症。
T26186	Sermetacin Sermetacina,SH G 318 AB,SHG 318 AB,TVX 3158
	Sermetacin is an anti-inflammatory agent.
T73702	Mecasermin
	Mecasermin（Human IGF-I; FK 780），一种重组人胰岛素样生长因子I（IGF-I），主要用于研究因生长激素（GH）受体缺陷或GH抑制抗体导致的GH不敏感性而引起的生长障碍。
T27322	Fispemifene HM-101,HM 101,HM101	Others	Others
	Fispemifene (HM-101) 是一种雌激素受体调节剂（SERM），可用于治疗泌尿生殖系统综合征和阴道萎缩。
T25534	Indazole-Cl Indazole Cl	Estrogen/progestogen Receptor	Endocrinology/Hormones
	Indazole-Cl 是一种选择性雌激素受体激动剂和选择性雌激素受体调节剂（SERM）。
T4420	4-Hydroxytamoxifen ICI 79280,(Z)-4-hydroxy Tamoxifen,4-羟基他莫昔芬,trans-4-Hydroxytamoxifen	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	4-Hydroxytamoxifen (ICI 79280) 是 Tamoxifen 的活性代谢产物，是一种雌激素受体调节剂 (SERM)，具有选择性和口服有效性。4-Hydroxytamoxifen 具有抗肿瘤活性，可用于乳腺癌的研究。
T15249	Estrogen receptor modulator 1	Estrogen Receptor/ERR	Endocrinology/Hormones
	Estrogen receptor modulator 1 是一种有效的、具有口服活性的、选择性雌激素受体(estrogen receptor)调节剂 (SERM)，其 pIC50为 0.46。它能够诱导 Tamoxifen 耐药、激素非依赖性异种移植瘤的消退。
T2569	Chlorotrianisene tris(p-methoxyphenyl)chloroethylene,氯丁烯二烯,CTA,tri-p-anisylchloroethylene,氯烯雌醚,TACE	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; COX	Endocrinology/Hormones; Immunology/Inflammation; Neuroscience
	Chlorotrianisene (tri-p-anisylchloroethylene) 是长效、可口服、亲脂性高的合成三苯乙烯 (TPE) 衍生物和选择性雌激素受体调节剂，有雌激素活性，也有抗雌激素活性。它还有效抑制COX-1并抑制全血中的血小板聚集。
T7839	Lasofoxifene Tartrate CP-336156,酒石酸拉索昔芬	Estrogen Receptor/ERR	Endocrinology/Hormones
	Lasofoxifene Tartrate (CP-336156) 是一种非甾体类的雌激素受体选择性调节剂 (SERM)。
T6620	Ospemifene FC-1271a,欧司哌米,奥培米芬	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Ospemifene (FC-1271a) 是非雌激素的选择性雌激素受体调节剂，能够作用于雌激素受体α (Kis:380 nM)和 Erβ (Kis:410 nM)。它可用于研究阴道萎缩乳腺癌。
T28957	TFR4OHT TFR-4-OHT,TFR 4 OHT
	TFR4OHT is a selective ER modulator (SERM).
T25700L	Levormeloxifene fumarate
	Levormeloxifene fumarate is an osteoporosis drug and selective estrogen receptor modulator (SERM).
T3645	Endoxifen E-isomer hydrochloride E-Endoxifen hydrochloride	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Endoxifen E-isomer hydrochloride (E-Endoxifen hydrochloride) 是 Endoxifen 的 E-异构体，是 Endoxifen Z-isomer 原料中主要的杂质，具有抗雌激素作用。
T27946	LY-329146 LY 329146
	LY-329146 is a selective estrogen receptor modulator (SERM). LY-329146 prevents doxorubicin resistance in tumor cells expressing multidrug resistance-associated protein (MRP) by inhibiting the binding of MRP substrates to the estrogen receptor.
T13076	Tamoxifen-d5 ICI 47699-d5,(Z)-Tamoxifen-d5,trans-Tamoxifen-d5	HSP	Cytoskeletal Signaling; Metabolism
	Tamoxifen-d5 is a deuterium labeled Tamoxifen. Tamoxifen is a selective modulator of estrogen receptor (SERM). Tamoxifen is a potent activator of Hsp90 and enhances the Hsp90 molecular chaperone ATPase activity.
T62119	Lasofoxifene
	Lasofoxifene (CP-336156) 是一种选择性的、口服具有活力的雌激素受体调节剂 (SERM)。Lasofoxifene 对原生肿瘤的生长和转移具有抑制作用，也能够抗骨质疏松。Lasofoxifene 能够用于研究乳腺癌和绝经后骨质疏松症。
T39259	Arzoxifene LY353381,Arzoxifene,SERMIII
	Arzoxifene (LY353381) is an orally active selective estrogen receptor modulator (SERM) exhibiting a fixed ring structure analogous to raloxifene. This compound demonstrates potent antiestrogenic effects on breast cancer and endometrium while displaying minimal side effects. Additionally, Arzoxifene elicits favorable estrogenic effects on bone health and lipid profile.
T71578	Endoxifen mesylate
	Endoxifen, also known as N-desmethyl-4-hydroxytamoxifen, is a chemical that is under development for estrogen receptor-positive breast cancer. It is also being evaluated as an antipsychotic for treatment of mania and other psychotic disorders. Endoxifen is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group. It is an active metabolite of tamoxifen and has been found to be effective in patients that have failed previous hormonal therapies (tamoxifen, aromat...
T79382	ER degrader 6	Estrogen Receptor/ERR	Endocrinology/Hormones
	ER degrader 6 (compound 35s) 是高效的雌激素受体 (ER)α降解剂，作用机制为通过抑制微管蛋白聚合破坏微管网络。该化合物能抑制肿瘤生长，并展现出较低的毒性特性。

化合物

Arzoxifene hydrochloride

Cat.No: T10379

Synonym: SERM 3,LY 353381 HCl

Target: Others

Bazedoxifene acetate

Cat.No: T2544

Synonym: 醋酸巴多昔芬,WAY-TES 424,TSE 424,WAY-140424

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Bazedoxifene hydrochloride

Cat.No: T6404

Synonym: Bazedoxifene HCl,盐酸巴多昔芬,TSE-424

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Cat.No: T26186

Synonym: Sermetacina,SH G 318 AB,SHG 318 AB,TVX 3158

Cat.No: T73702

Cat.No: T27322

Synonym: HM-101,HM 101,HM101

Target: Others

Cat.No: T25534

Synonym: Indazole Cl

Target: Estrogen/progestogen Receptor

4-Hydroxytamoxifen

Cat.No: T4420

Synonym: ICI 79280,(Z)-4-hydroxy Tamoxifen,4-羟基他莫昔芬,trans-4-Hydroxytamoxifen

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Estrogen receptor modulator 1

Cat.No: T15249

Target: Estrogen Receptor/ERR

Chlorotrianisene

Cat.No: T2569

Synonym: tris(p-methoxyphenyl)chloroethylene,氯丁烯二烯,CTA,tri-p-anisylchloroethylene,氯烯雌醚,TACE

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, COX

Lasofoxifene Tartrate

Cat.No: T7839

Synonym: CP-336156,酒石酸拉索昔芬

Target: Estrogen Receptor/ERR

Cat.No: T6620

Synonym: FC-1271a,欧司哌米,奥培米芬

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Cat.No: T28957

Synonym: TFR-4-OHT,TFR 4 OHT

Levormeloxifene fumarate

Cat.No: T25700L

Endoxifen E-isomer hydrochloride

Cat.No: T3645

Synonym: E-Endoxifen hydrochloride

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Cat.No: T27946

Synonym: LY 329146

Cat.No: T13076

Synonym: ICI 47699-d5,(Z)-Tamoxifen-d5,trans-Tamoxifen-d5

Target: HSP

Cat.No: T62119

Cat.No: T39259

Synonym: LY353381,Arzoxifene,SERMIII

Endoxifen mesylate

Cat.No: T71578

Cat.No: T79382

Target: Estrogen Receptor/ERR

Cat. No.	Product Name	Target	Signaling Pathways
T24002	Disermolide XAA 296,XAA296,XAA-296
	Disermolide is a polyketide natural product found to stabilize microtubules. Disermolide was found to be a potent inhibitor of tumor cell growth in several MDR cancer cell lines.
T1549	Raloxifene hydrochloride LY156758 hydrochloride,盐酸雷洛昔芬,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl	Estrogen Receptor/ERR; Others; MAO; Estrogen/progestogen Receptor; Autophagy	Autophagy; Endocrinology/Hormones; Metabolism; Neuroscience; Others
	Raloxifene hydrochloride (LY156758 hydrochloride) 是一种选择性且可口服的雌激素受体调节剂，用于预防绝经后妇女的骨质疏松症。它对骨骼和胆固醇代谢具有雌激素激动作用，但对乳腺和子宫组织具有完全的雌激素拮抗作用。

天然产物

Cat.No: T24002

Synonym: XAA 296,XAA296,XAA-296

Raloxifene hydrochloride

Cat.No: T1549

Synonym: LY156758 hydrochloride,盐酸雷洛昔芬,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl

Target: Estrogen Receptor/ERR, Others, MAO, Estrogen/progestogen Receptor, Autophagy

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼