|
TMPY-00649
|
MIP-1 alpha/CCL3 Protein, Human, Recombinant (His)
LD78α,chemokine (C-C motif) ligand 3,MIP-1-alpha,G0...
|
Human
|
Yeast
|
|
CCL3 is a cytokine belonging to the CC chemokine family. Chemokines are a family of structurally related leukocyte chemoattractant cytokines that play a central role during immunoregulatory and inflammation processes. All chemokines contain four conserved cysteines linked by disulfide bonds, and two major subfamilies, namely CXC and CC, are defined on the basis of the first two cysteines which are separated by one amino acid or are adjacent. CCL3 is involved in the acute inflammatory state in th... |
|
TMPY-00695
|
I-309 Protein, Human, Recombinant (hFc)
chemokine (C-C motif) ligand 1,TCA3,SISe,I-309,...
|
Human
|
HEK293
|
|
CCL1 or chemokine (C-C motif) ligand 1, also known as I-309 or TCA-3, is a member of the chemokine (C-C motif) ligand family. The C-C chemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands (CCL)-1 to 28. I-309/CCL1/TCA-3 interacts with the G protein-linked transmembrane chemokine receptors CCR8 and induces biochemical events that may result in the control of chemotaxis, proliferatio... |
|
TMPY-00566
|
CCL18 Protein, Human, Recombinant (His)
PARC,CCL18,CKb7,DC-CK1,chemokine (C-C moti...
|
Human
|
Yeast
|
|
CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its potential as a circulating biomarker. CCL18 chemokine has an important role in chemokine-mediated tumor metastasis, and may serve as a potential predictor for poor survival outcomes for ovarian cancer. (CCL18) is predominantly secreted by M2-tumor associated macrophages (TAMs) a... |
|
TMPY-00118
|
MCP-1/CCL2 Protein, Human, Recombinant (His)
SCYA2,HC11,MCAF,HSMCR30,MCP-1...
|
Human
|
Yeast
|
|
Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. MCP-1 protein interacts with chemokine C-C motif receptor 2 (CCR2) to activate and recruit monocytes, macrophages, CD4+ T cells and immature dendritic cells to the site of infection. The presence of MCP-1 protein in an adequate concentration is important for granuloma formation and M. tuberculosis clearance.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted The... |
|
TMPY-00646
|
CCL4 Protein, Human, Recombinant (His)
SCYA2,G-26,MIP-1-β,LAG-1,MIP1...
|
Human
|
Yeast
|
|
CCL4 (C-C chemokine ligand 4), is a macrophage inflammatory protein with a chief effect in inflammation and immune-regulation, and was documented in cancer progression by promoting instability in the tumor environment. The inflammatory chemokine (C-C motif) ligand 4 (CCL4) plays an important role in the pathogenesis and progression of cancer. In particular, higher serum CCL4 levels in patients with oral squamous cell carcinoma (OSCC) are associated with a more advanced stage of disease. CCL4 may... |
|
TMPY-03728
|
CCL28 Protein, Human, Recombinant (His)
MEC,SCYA28,chemokine (C-C motif) ligand 28,CCK1...
|
Human
|
E. coli
|
|
CCL28 chemokine is expressed by epithelial cells of various mucosal tissues. This chemokine binds to CCR3 and CCR10 receptors and plays an essential role in the IgA antibody secreting cells (IgA-ASC) homing to mucosal surfaces and lactating mammary gland as well. Besides, CCL28 has been shown to exert a potent antimicrobial activity against both Gram-negative and Gram-positive bacteria and fungi. The potent antimicrobial function of CCL28 combined with its wide distribution in mucosal tissues an... |
|
TMPY-03071
|
I-309 Protein, Human, Recombinant
SISe,P500,TCA3,I-309,chemokine (C-C motif) ligand 1...
|
Human
|
E. coli
|
|
CCL1 or chemokine (C-C motif) ligand 1, also known as I-309 or TCA-3, is a member of the chemokine (C-C motif) ligand family. The C-C chemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands (CCL)-1 to 28. I-309/CCL1/TCA-3 interacts with the G protein-linked transmembrane chemokine receptors CCR8 and induces biochemical events that may result in the control of chemotaxis, proliferatio... |
|
TMPY-05353
|
CCL26 Protein, Human, Recombinant
MIP-4alpha,SCYA26,MIP-4a,chemokine (C-C motif) liga...
|
Human
|
Baculovirus-Insect Cells
|
|
The eotaxin subfamily of CC chemokines consists of eotaxin-1/CCL11, eotaxin-2/CCL24 and eotaxin-3/CCL26. All eotaxins induce the trafficking of eosinophils to the sites of inflammation via CC chemokine receptor 3 (CCR3), which is also expressed by several different cell types, including basophils, dendritic cells, smooth muscle cells, epithelial cells and fibroblasts. The sequence similarity between the three eotaxins is limited (<4%), but their functional properties are very similar. Eotaxin-1 ... |
|
TMPY-02756
|
MDC Protein, Human, Recombinant (His)
A-152E5.1,MDC,ABCD-1,SCYA
|
Human
|
E. coli
|
|
Chemokine (C-C motif) ligand 22(ABCD-1 / CCL22)is a kind of CC chemokine which is a family of secreted proteins involved in immunoregulatory and inflammatory processes. The cytokine displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. This ABCD-1 / CCL22 chemokine... |
|
TMPY-00564
|
MCP-4 Protein, Human, Recombinant (His)
MCP-4,CCL13,SCYL1,NCC-1,MCP4,NCC<...
|
Human
|
Yeast
|
|
Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eosinphils to inflammatory sites. CCL13/MCP-4, is a CC family chemokine that is chemoattractant for eosinophils, basophils, monocytes, macrophages, immature dendritic cells, and T cells, and its capable of inducing crucial immuno-modulatory responses through its effects on epithelial, muscular and endothelial cells. Similar to other CC chem... |
|
TMPK-00011
|
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated
SMC-CF,HC11,MCAF,MCP1,MCP-1
|
Human
|
HEK293
|
|
Monocyte chemotactic protein-1 (MCP-1) (also referred to as chemokine (C-C motif) ligand 2 (CCL2) is expressed by mainly inflammatory cells and endothelial cells. MCP-1 has been reported to play an important role in the pathogenesis of atherosclerosis and considerable evidence supports that the monocyte containing MCPs and macrophage influences the growth of other cell types within the atherosclerotic lesion. This review will focus on the general structure features of MCP-1 and its role in ather... |
|
TMPK-00010
|
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi)
MCP-1,MCAF,GDCF-2,SMC-CF,C-C motif chemokine 2,...
|
Human
|
HEK293
|
|
Monocyte chemotactic protein-1 (MCP-1) (also referred to as chemokine (C-C motif) ligand 2 (CCL2) is expressed by mainly inflammatory cells and endothelial cells. MCP-1 has been reported to play an important role in the pathogenesis of atherosclerosis and considerable evidence supports that the monocyte containing MCPs and macrophage influences the growth of other cell types within the atherosclerotic lesion. This review will focus on the general structure features of MCP-1 and its role in ather... |
|
TMPY-00641
|
LEC/CCL16 Protein, Human, Recombinant (His)
SCYL4,HCC-4,ILINCK,LMC,SCYA16,NCC-4,CKb
|
Human
|
E. coli
|
|
CCL16, a chemokine poorly characterized at the functional level. Human CCL16 is a member of the CC family, and its gene maps to human chromosome 17q. In the mouse, only a pseudogene has been identified to date. CCL16 is a functional ligand for CCR1, CCR2, CCR5, and CCR8. Recombinant CCL16 demonstrated chemotactic activity on human monocytes and lymphocytes. Based on the ability of human chemokines to exert activity on and bind to murine receptors, the TSA mouse adenocarcinoma cell line was trans... |
|
TMPK-00916
|
MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His)
MCP-1,MCP1,SCYA2,GDCF-2,MCAF,CCL2...
|
Cynomolgus
|
HEK293
|
|
Monocyte chemotactic protein-1 (MCP-1) (also referred to as chemokine (C-C motif) ligand 2 (CCL2) is expressed by mainly inflammatory cells and endothelial cells. MCP-1 has been reported to play an important role in the pathogenesis of atherosclerosis and considerable evidence supports that the monocyte containing MCPs and macrophage influences the growth of other cell types within the atherosclerotic lesion. This review will focus on the general structure features of MCP-1 and its role in ather... |
|
TMPY-02468
|
CCL14 Protein, Human, Recombinant (aa 28-93, His)
MCIF,HCC-3,CC-3,chemokine (C-C motif) ligand 14,FLJ...
|
Human
|
E. coli
|
|
CCL14 has an important biological role in other mammals by evolving under positive selection that has been lost in Ochotonidae (subgenera Pika and Lagotona). CC chemokine ligand 14, CCL14, is a human CC chemokine that is of recent interest because of its natural ability, upon proteolytic processing of the first eight NH2-terminal residues, to bind to and signal through the human immunodeficiency virus type-1 (HIV-1) co-receptor, CC chemokine receptor 5 (CCR5). Embryo implantation is a complex pr... |
|
TMPY-03886
|
MPIF-1/CCL23 Protein, Human, Recombinant
SCYA23,CKb8,Ckb-8,MPIF-1,MPIF1,ch...
|
Human
|
E. coli
|
|
CCL23, also known as MIP 3, is a small cytokine which belongs to the CC chemokine family. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. CCL23 is predominantly expressed in lung and liver tissue, but also can be detected in bone marrow and placenta. It displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. CCL23 is also a strong suppressor of colony forma... |
|
TMPY-02257
|
CCL14 Protein, Human, Recombinant (His)
HCC-3,CKB1,SCYA14,chemokine (C-C ...
|
Human
|
E. coli
|
|
CCL14 has an important biological role in other mammals by evolving under positive selection that has been lost in Ochotonidae (subgenera Pika and Lagotona). CC chemokine ligand 14, CCL14, is a human CC chemokine that is of recent interest because of its natural ability, upon proteolytic processing of the first eight NH2-terminal residues, to bind to and signal through the human immunodeficiency virus type-1 (HIV-1) co-receptor, CC chemokine receptor 5 (CCR5). Embryo implantation is a complex pr... |
|
TMPY-02688
|
MIP-5 Protein, Human, Recombinant (aa 46-113, His)
HMRP-2B,chemokine (C-C motif) ligand 15,MIP-5,SY
|
Human
|
E. coli
|
|
Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling... |
|
TMPY-00168
|
MPIF-1/CCL23 Protein, Human, Recombinant (His)
MIP3,MIP-3,Ckb-8-1,CK-BETA-8,Ckb-8,MPIF-1,...
|
Human
|
Yeast
|
|
CCL23, also known as MIP 3, is a small cytokine which belongs to the CC chemokine family. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. CCL23 is predominantly expressed in lung and liver tissue, but also can be detected in bone marrow and placenta. It displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. CCL23 is also a strong suppressor of colony forma... |
|
TMPY-02075
|
MIP-5 Protein, Human, Recombinant (aa 22-113, His)
LKN-1,MIP-5,SY15,MIP-1 δ,MIP-...
|
Human
|
E. coli
|
|
Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling... |
|
TMPJ-00018
|
CCL16 Protein, Human, Recombinant
NCC-4,Lymphocyte and Monocyte Chemoattractant,LMC,NCC4,HCC-4...
|
Human
|
E. coli
|
|
CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC chemokines, showing less than 30% sequence identity. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8. Recombinant CCL16 has been shown to chemoattract human monocytes and THP1 cells but not resting lymphocyt... |
|
TMPJ-00005
|
CCL3 Protein, Human, Recombinant
MIP-1-Alpha,CCL3,MIP-1-α,Small-Inducible C...
|
Human
|
E. coli
|
|
Human Chemokine (C-C Motif) Ligand 3 (CCL3) is a small cytokine belonging to the CC chemokine family. CCL3 is primarily expressed in T cells, B cells, and monocytes after antigen or mitogen stimulation. CCL3 exhibits chemoattractive and adhesive effects on lymphocytes. CCL3 exerts multiple effects on hematopoietic precursor cells and inhibits the proliferation of hematopoietic stem cells in vitro as well as in vivo. CCR1 and CCR5 have been identified as functional receptors for CCL3. |
|
TMPY-04451
|
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
AMPK, AMPK(α1, β1, γ1)
|
Human
|
Baculovirus-Insect Cells
|
|
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus-Insect Cells |
|
TMPY-03878
|
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...
|
Human
|
HEK293
|
|
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of ITGAV&ITGB6 via clathrin-med... |
|
TMPY-02501
|
CD3D & CD3E Heterodimer Protein, Human, Recombinant
CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...
|
Human
|
HEK293
|
|
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 cells. |
|
TMPY-03745
|
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
CD3-DELTA,CD3d molecule, delta (CD3-TCR complex),CD3d molecu...
|
Human
|
HEK293
|
|
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 31.05 kDa. Accession number: P04234-1&P07766-1 |
|
TMPY-00664
|
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)
Angiopoietin-2,AGPT2,angiopoietin 2,ANG2
|
Human
|
HEK293
|
|
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine kinase receptor, Tie-2, found primarily on the luminal surface of endothelial cells. ANG-2's role in angiogenesis generally is considered as an antagonist for ANG1, inhibiting ANG1-promoted Tie2 signaling, which is critical for blood vessel maturation and stabilization. ANG-2 mod... |
|
TMPY-01298
|
CADM1 Protein, Human, Recombinant (His)
Necl-2,cell adhesion molecule 1,SYNCAM,BL2,sTSLC-
|
Human
|
HEK293
|
|
Members of the immunoglobulin superfamily often play key roles in intercellular adhesion. IGSF4 is a novel immunoglobulin (Ig)-like intercellular adhesion molecule. Three Ig-like domains are included in the extracellular domain of IGSF4 and mediate homophilic or heterophilic interactions independently of Ca2+. The cytoplasmic domain of IGSF4 contains the binding motifs that connect to actin fibers. Since IGSF4 has been characterized by several independent research groups, this molecule is called... |
|
TMPY-04779
|
BTN3A2 Protein, Human, Recombinant (His)
BTF3,BT3.2,BTF4,BTN3.2,CD277,butyrophilin subfamily 3 member...
|
Human
|
HEK293
|
|
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tumors, and deletion of BTN3A2 inhibited proliferation, migration, and invasion of gastric cancer cells. The butyrophilin 3 (BTN3) receptors are implicated in the T lymphocytes regulation and present a wide plasticity in mammals. A thorough phylogenetic analysis reveals a concerted... |
|
TMPY-03363
|
C-Reactive Protein Protein, Human, Recombinant
C-Reactive Protein,C-reactive protein, pentraxin-related,PTX...
|
Human
|
HEK293
|
|
C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reactive protein (CRP) is the classical acute phase reactant, the circulating concentration of which rises rapidly and extensively in a cytokine-mediated response to tissue injury, infection and inflammation. Serum CRP values are routinely measured, empirically, to detect and monit... |
|
TMPY-02512
|
Alpha-Synuclein Protein, Human, Recombinant
PD1,α-Synuclein,PARK4,synuclein, α (non A4 componen...
|
Human
|
E. coli
|
|
Alpha-Synuclein (alpha-Syn), also known as NACP or SNCA, exists as at least two structural isoforms: one is helix-rich, membrane-bound form that both the N- and C-terminal regions of alpha-synuclein are tightly associated with membranes and the other is disordered, cytosolic form. Synuclein is found predominantly in the presynaptic termini, in both free or membrane-bound forms. SNCA is extensively localized in nucleus of neurons. It has been shown that alpha-Synuclein was highly expressed in the... |
|
TMPY-05354
|
CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD28 molecule,Tp44
|
Human
|
HEK293
|
|
CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell r... |
|
TMPY-00586
|
CLEC-2 Protein, Mouse, Recombinant (hFc)
1810061I13Rik,Clec2,C-ty...
|
Mouse
|
HEK293
|
|
CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and... |
|
TMPY-04824
|
CTLA-4 Protein, Human, Recombinant
CTLA-4,GSE,IDDM12,CELIAC3,ALPS5,CD,GRD4,cytotoxic T...
|
Human
|
HEK293
|
|
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands or counterreceptors for these two proteins are the B7 family members, CD80 (B7-1) and CD86 (B7-2). CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may play an important role i... |
|
TMPY-00986
|
IL-34 Protein, Mouse, Recombinant (His)
interleukin 34,2010004A03Rik,AI593503
|
Mouse
|
HEK293
|
|
IL34 (Interleukin 34) is a Protein Coding gene. IL-34, also known as uncharacterized protein C16 or f77 homolog, belongs to the IL-34 family. IL-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R). IL-34 protein is expressed in various tissues, including heart, brain, lung, liver, kidney, spleen, thymus, testes, ovary, small intestine, prostate, and colon, and most abundant in the spleen. The colon... |
|
TMPY-03273
|
IL-18 Protein, Mouse, Recombinant
interleukin 18,白细胞介素,白介素,Il-18,Igif
|
Mouse
|
E. coli
|
|
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of IL-18 and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its bi... |
|
TMPY-02412
|
ENO1 Protein, Human, Recombinant (His)
PPH,NNE,enolase 1, (alpha),ENO1L1...
|
Human
|
E. coli
|
|
The ENO1 gene encodes a multifunctional enzyme that has been identified as a key component of the glycolytic pathway. ENO1 overexpression and post-translational modifications could be of diagnostic and prognostic value in many cancer types. The results of the ENO1 expression profiling of ovarian follicles suggest that ENO1 may play an important dual role in the progress of follicular development, where ENO1 acts as a glycolytic enzyme and also mediates apoptosis. ENO1 overexpression could make ... |
|
TMPY-01834
|
CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His)
CD16,Fc receptor, IgG, low affinity III
|
Mouse
|
HEK293
|
|
Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as... |
|
TMPY-01912
|
Cadherin 17/CDH17 Protein, Human, Recombinant (His)
HPT-1,cadherin 17, LI cadherin (liver-inte...
|
Human
|
HEK293
|
|
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular region, 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of ... |
|
TMPY-01055
|
IL-4R Protein, Human, Recombinant (His)
interleukin 4 receptor,IL4RA,IL4R,CD124,IL-4RA
|
Human
|
HEK293
|
|
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins ... |
|
TMPY-01608
|
Decorin Protein, Human, Recombinant (His)
PGS2,PG40,CSCD,decorin,SLRR1B,DSPG2,PGII
|
Human
|
HEK293
|
|
Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core protein and a covalently linked glycosaminoglycan chain which is either chondroitin sulfate (CS) or dermatan sulfate (DS). As a component of connective tissue, decorin interacts with several extracellular matrix components, such as type I collagen and fibronectin, and plays a role... |
|
TMPY-04810
|
CD47 Protein, Mouse, Recombinant (His)
AA407862,CD47 molecule,AW108519,91
|
Mouse
|
HEK293
|
|
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the b... |
|
TMPY-01280
|
FOLR2 Protein, Human, Recombinant (His)
FBP,β-HFR,FR-P3,BETA-HFR,folate receptor 2 (fetal),FR-BETA,F...
|
Human
|
HEK293
|
|
Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potoc... |
|
TMPY-00843
|
IL-25/IL17E Protein, Human, Recombinant (hFc)
interleukin 25,IL17E
|
Human
|
HEK293
|
|
Interleukin-25 (IL-25) is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. IL-25 is a member of the IL-17 family of cytokines. However, unlike the other members of this family, IL-25 promotes T helper (Th) 2 responses. IL-25 also regulates the development of autoimmune inflammation mediated by IL-17–produ... |
|
TMPY-01462
|
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)
interleukin 11 receptor subunit alpha,hCG_...
|
Human
|
HEK293
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Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, including the myelogenous leukemia cell line K562, the megakaryocytic leukemia cell line Mo7E, the erythroleukemia cell line TF1, and the osteosarcoma cell lines, MG-63 and Saos-2. It is also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increas... |
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TMPY-05277
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IL-4R Protein, Human, Recombinant (hFc)
IL4R,IL4RA,CD124,IL-4RA,interleukin 4 receptor
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Human
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HEK293
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The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins ... |
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TMPY-03256
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NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His)
KLR,killer cell lectin-like receptor subfamily K, member
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Human
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Baculovirus-Insect Cells
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KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular proteins incapable to transduce signals. To transduce signals, NKG2D needs adaptor proteins and it uses two adaptor proteins, DAP10 and DAP12. These two adaptor proteins associate as homodimers to NKG2D- therefore the entire receptor complex appears as a hexamer. NKG2D can send co-stim... |
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TMPY-05579
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PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated
PRR1,ED4,PVRR,nectin-1,OFC7,SK-12...
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Human
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HEK293
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Poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin-1; CD111), also known as PVRL1 is a cell adhesion molecule belonging to the immunoglobulin superfamily that can bind to virion glycoprotein D (gD) to mediate entry of herpes simplex viruses (HSV) and pseudorabies virus (PRV). CD111/Nectin-1/PVRL1 colocalizes with E-cadherin at adherens junctions in epithelial cells. The disruption of cell junctions can result in the redistribution of nectin-1. To determine whether disruption of ... |
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TMPY-00939
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Thrombopoietin Protein, Mouse, Recombinant (His)
thrombopoietin,Mpllg,Tpo,Mgdf,Ml
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Mouse
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HEK293
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Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. Thrombopoietin protein stimulates both proliferation of progenitor megakaryocytes and their maturation to platelet-producing megakaryocytes, and also accelerates the recovery of platelets. Thrombopoietin... |
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TMPY-05435
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ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)
angiopoietin 1,AGPT,AGP1,ANG1
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Human
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HEK293
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The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In disease, ANGPT2-mediated inhibition of TIE2 in blood vessels is linked to vascular leak, inflammation, and metastasis. Primary congenital glaucoma (PCG) is a leading cause of blindness in children worldwide and is caused by developmental defects in 2 aqueous humor outflow structures... |
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