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Cat. No. Product Name Target Signaling Pathways
T0684 Ribavirin

Tribavirin,ICN-1229,NSC-163039,利巴韦林,RTCA

Dehydrogenase; HCV Protease; DNA/RNA Synthesis; Antibiotic; AChR; RSV Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Ribavirin (Tribavirin) 是一种合成的呋喃核苷类似物,具有抗丙型肝炎病毒和其他 RNA 病毒的活性。
T38297 Ribavirin-13C5

Ribavirin-13C5

Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to an active triphosphate form that induces viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 μg/ml).3Ribavirin also reduces replication of severe acute respiratory syndrome coro...
T23938 D4-Ribavirin

D4Ribavirin,D4 Ribavirin

D4-Ribavirin is isolated from the brine shrimp active fraction of the MeOH extract of the starfish Certonardoa semiregular.
T25702 Levovirin

ICN 17261,L-Ribavirin,ICN-17261,ICN17261

Levovirin is a monocyclic L-nucleosides with type 1 cytokine-inducing activity. Levovirin is the L-enantiomer of Ribavirin. Levovirin has similar immunomodulatory activity but does not have direct antiviral activity or hemolytic anemia.
T37877 Ribavirin 5'-monophosphate (lithium salt)

Ribavirin 5'-monophosphate (lithium salt)对 IMP 脱氢酶(将 IMP 转化为 XMP)具体直接抑制作用
TNU0339 Ribavirin carboxylic acid

Nucleoside Derivatives - Other modified nucleosides; Drugs and Inhibitors; Ribavirin related compound A; metabolite of Ribavirin
T16993 Taribavirin

Others Others
Taribavirin is an orally active inosine monophosphate dehydrogenase inhibitor. Taribavirin is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of he
T16992 Taribavirin hydrochloride

Others Others
Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor. Taribavirin hydrochloride is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells and
T27586 IDX184

IDX-184,IDX 184

HCV Protease Microbiology/Virology; Proteases/Proteasome
IDX184 是一种有效的,具有口服活性的靶向 HCV 聚合酶抑制剂和核苷聚合酶抑制剂。IDX184 有效抑制 HCV 聚合酶 (IC50=0.31 μM,Ki=52.3 nM)。 IDX184是一种肝脏靶向核苷酸前药,具有抗HCV活性,可抑制HCV NS5B聚合酶,可与聚乙二醇化干扰素-α2a 和利巴韦林联合用于初治慢性丙型肝炎。
T70846 Deleobuvir sodium

Deleobuvir sodium is the salt form of Deleobuvir, also known as BI207127, a non-nucleoside hepatitis C virus NS5B polymerase inhibitor for the treatment of hepatitis C. Deleobuvir was tested in combination regimens with pegylated interferon and ribavirin, and in interferon-free regimens with other direct-acting antiviral agents including faldaprevir. Deleobuvir showed that a triple combination of deleobuvir, faldaprevir, and ribavirin performed well in HCV genotype 1b patients. Efficacy fell b...
T61291 RSV/IAV-IN-2

RSV/IAV-IN-2 (compound 14c) 是一种有效的 RSV/IAV 双重抑制剂。RSV/IAV-IN-2 的细胞毒性低于临床药物利巴韦林。RSV/IAV-IN-2 具有研究 RSV 和/或 IAV 感染的潜力。
T79219 RSV L-protein-IN-3

RSV Microbiology/Virology
RSVL-protein-IN-3为一野生型RSV聚合酶抑制剂,具IC50值10.4 μM及EC50值2.1 μM(RSV)。相较之下,RSV/IAV-IN-2之细胞毒性显著低于临床活性分子Ribavirin
T61343 RSV/IAV-IN-1

RSV/IAV-IN-1 (compound 14e) 是一种有效的 RSV/IAV 双重抑制剂。RSV/IAV-IN-1 的细胞毒性低于临床药物利巴韦林。RSV/IAV-IN-1 具有研究 RSV 和/或 IAV 感染的潜力。
T14493 Balapiravir

R1626,Ro 4588161

Others Others
Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479). IC50 Value: Target: HCV Balapiravir was discontinued for safety reasons in 28-36% of patients (m

化合物

Ribavirin
Cat.No: T0684
Synonym: Tribavirin,ICN-1229,NSC-163039,利巴韦林,RTCA
Target: Dehydrogenase, HCV Protease, DNA/RNA Synthesis, Antibiotic, AChR, RSV
Ribavirin-13C5
Cat.No: T38297
Synonym: Ribavirin-13C5
Target:
D4-Ribavirin
Cat.No: T23938
Synonym: D4Ribavirin,D4 Ribavirin
Target:
Levovirin
Cat.No: T25702
Synonym: ICN 17261,L-Ribavirin,ICN-17261,ICN17261
Target:
Ribavirin 5'-monophosphate (lithium salt)
Cat.No: T37877
Synonym:
Target:
Ribavirin carboxylic acid
Cat.No: TNU0339
Synonym:
Target:
Taribavirin
Cat.No: T16993
Synonym:
Target: Others
Taribavirin hydrochloride
Cat.No: T16992
Synonym:
Target: Others
IDX184
Cat.No: T27586
Synonym: IDX-184,IDX 184
Target: HCV Protease
Deleobuvir sodium
Cat.No: T70846
Synonym:
Target:
RSV/IAV-IN-2
Cat.No: T61291
Synonym:
Target:
RSV L-protein-IN-3
Cat.No: T79219
Synonym:
Target: RSV
RSV/IAV-IN-1
Cat.No: T61343
Synonym:
Target:
Balapiravir
Cat.No: T14493
Synonym: R1626,Ro 4588161
Target: Others
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