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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T28877 |
SU9518
SU 9518,5-Br-SU6668,SU-9518,5 Br SU6668,5BrSU6668 |
||
SU9518, a tyrosine kinase inhibitor with PDGFRα specificity, can inhibit the development of proliferative vitreoretinopathy (PVR) in fibroblast and Müller cell rabbit models. | |||
T78324 |
Ociperlimab
BGB-A1217 |
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Ociperlimab 是一种人源化IgG1抗TIGIT抗体,能以高亲和力(KD= 0.135 nM)结合于TIGIT的细胞外结构域,并阻断其与配体PVR或PVR-L2之间的相互作用,适用于癌症研究。 | |||
T82436 |
Etigilimab
OMP-313M32 |
||
Etigilimab (OMP-313M32) 为人源化IgG1单克隆抗体,旨在阻断TIGIT与PVR (CD155;脊髓灰质炎病毒受体)间的结合,进而抑制信号传导,通过诱导靶细胞凋亡实现其作用。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00651 |
CD155/PVR Protein, Human, Recombinant (aa 21-343, His)
Poliovirus Receptor,PVS,Nectin-Like Protein 5,NECL-5,CD155,<... |
Human | HEK293 Cells |
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension be... | |||
TMPY-01612 |
CD155/PVR Protein, Rhesus, Recombinant (His)
poliovirus receptor |
Rhesus | HEK293 Cells |
CD155/PVR Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.8 kDa and the accession number is Q0MSE6. | |||
TMPK-00260 |
CD155/PVR Protein, Human, Recombinant (His & Avi)
NECL5,PVSFLJ25946,Necl-5,CD155,Tage4,PVR,HVED,FLJ25... |
Human | HEK293 Cells |
CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR. | |||
TMPY-05791 |
CD155/PVR Protein, Mouse, Recombinant (mFc)
Taa1,3830421F03Rik,poliovirus receptor,necl-5,D7Ertd458e,HVE... |
Mouse | HEK293 Cells |
CD155/PVR Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 60.78 kDa and the accession number is Q8K094. | |||
TMPY-00699 |
CD155/PVR Protein, Human, Recombinant (hFc)
poliovirus receptor,NECL5,HVED,PVS,Necl-5,TAGE4,CD155 |
Human | HEK293 Cells |
CD155/PVR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.8 kDa and the accession number is P15151-1. | |||
TMPY-01386 |
CD155/PVR Protein, Human, Recombinant (His)
NECL5,TAGE4,PVS,CD155,HVED,Necl-5,poliovirus receptor |
Human | HEK293 Cells |
CD155/PVR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P15151-1. | |||
TMPY-00762 |
CD155/PVR Protein, Mouse, Recombinant (His)
poliovirus receptor,D7Ertd458e,mE4,Taa1,necl-5,PVS,3830421F0... |
Mouse | HEK293 Cells |
CD155/PVR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28 kDa and the accession number is Q8K094. | |||
TMPY-01150 |
Nectin-2 Protein, Mouse, Recombinant (His)
MPH,Pvs,Pvr,Cd112,AI325026,AI987993,poliovirus rece... |
Mouse | HEK293 Cells |
Nectin-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36 kDa and the accession number is P32507-1. | |||
TMPY-05596 |
CD155/PVR Protein, Human, Recombinant (His & Avi), Biotinylated
NECL5,Necl-5,TAGE4,HVED,CD155,PVS,poliovirus receptor |
Human | HEK293 Cells |
CD155/PVR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 38.3 kDa and the accession number is P15151.2. | |||
TMPY-01610 |
CD155/PVR Protein, Rat, Recombinant (His)
poliovirus receptor |
Rat | HEK293 Cells |
CD155/PVR Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.8 kDa and the accession number is A6J8V8. | |||
TMPY-06133 |
CD155/PVR Protein, Human, Recombinant (hFc & Avi), Biotinylated
TAGE4,CD155,NECL5,poliovirus receptor,HVED,Necl-5,PVS |
Human | HEK293 Cells |
CD155/PVR Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 63.6 kDa and the accession number is P15151-1. | |||
TMPY-05597 |
CD155/PVR Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
PVS,Taa1,Tage4,CD155,poliovirus receptor,mE4,D7Ertd458e,HVED... |
Mouse | HEK293 Cells |
CD155/PVR Protein, Mouse, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 62.9 kDa and the accession number is Q8K094. | |||
TMPY-06094 |
PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His)
|
Cynomolgus,Rhesus | HEK293 Cells |
PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.3 kDa and the accession number is XP_005549281.1&XP_014989941.2. | |||
TMPY-05579 |
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated
PRR1,ED4,PVRR,nectin-1,OFC7,SK-12,CD111,CLPED1,HVEC... |
Human | HEK293 Cells |
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1. | |||
TMPK-00471 |
PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
MGC2463,MGC104322,LPD,C7orf15,ALS2CR18,PREL2,ALS2CR9,RMO1,PR... |
Mouse | HEK293 Cells |
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth. PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 42.7 kDa and the accession number is ... | |||
TMPK-00470 |
PVRIG Protein, Mouse, Recombinant (hFc & Avi)
PREL-2,RMO1,MGC2463,C7orf15,MGC104322,PREL2,PVRIG,L... |
Mouse | HEK293 Cells |
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth. PVRIG Protein, Mouse, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 42.70 kDa and the accession number is A0A1B0GS01. | |||
TMPJ-00428 |
PVRIG Protein, Mouse, Recombinant (hFc)
MGC138297,transmembrane protein PVRIG,MGC104322, |
Mouse | HEK293 Cells |
PVRIG Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 48-55 KDa and the accession number is A0A1B0GS01. | |||
TMPJ-00436 |
PVRIG Protein, Cynomolgus, Recombinant (His)
CD112R,C7orf15MGC138295,MGC104322,transmembrane protein ... |
Cynomolgus | HEK293 Cells |
PVRIG Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 20-30 KDa and the accession number is A0A2K5WVV8. | |||
TMPY-05560 |
PVRL1/NECTIN1 Protein, Mouse, Recombinant (His)
PRR1,PRR,nectin-1,HIgR,Cd111,AI835281,HveC,poliovirus recept... |
Mouse | HEK293 Cells |
PVRL1/NECTIN1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is Q9JKF6. | |||
TMPY-01572 |
PVRL1/NECTIN1 Protein, Human, Recombinant (His)
HVEC,ED4,PRR1,PVRR1,nectin-1,HIgR,poliovirus recept... |
Human | HEK293 Cells |
PVRL1/NECTIN1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.4 kDa and the accession number is Q15223-1. | |||
TMPY-05165 |
PVRIG Protein, Human, Recombinant (hFc)
C7orf15,PREL-2,RalGDS/AF-6,RMO1,ALS2CR18,LPD,ALS2CR9,PREL2 |
Human | HEK293 Cells |
PVRIG Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.9 kDa and the accession number is Q6DKI7. | |||
TMPY-06277 |
PVRIG Protein, Human, Recombinant (mFc)
C7orf15,RMO1,ALS2CR18,LPD,ALS2CR9,RalGDS/AF-6,PREL-2,PREL2 |
Human | HEK293 Cells |
PVRIG Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 40.15 kDa and the accession number is Q6DKI7-1. | |||
TMPY-03030 |
PVRL1/NECTIN1 Protein, Rat, Recombinant (hFc)
poliovirus receptor-related 1 (herpesvirus entry mediator C) |
Rat | HEK293 Cells |
PVRL1/NECTIN1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63.3 kDa and the accession number is A6J3U6. | |||
TMPY-06301 |
PVRIG Protein, Human, Recombinant (hFc & Avi), Biotinylated
ALS2CR9,ALS2CR18,RalGDS/AF-6,PREL-2,LPD,C7orf15,PREL2,RMO1 |
Human | HEK293 Cells |
PVRIG Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 42.31 kDa and the accession number is Q6DKI7-1. | |||
TMPJ-00435 |
PVRIG Protein, Cynomolgus, Recombinant (hFc)
C7orf15MGC138295,MGC138297,CD112R,MGC104322,transmembrane pr... |
Cynomolgus | HEK293 Cells |
PVRIG Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-55 KDa and the accession number is A0A2K5WVV8. | |||
TMPY-05196 |
PVRL1/NECTIN1 Protein, Mouse, Recombinant (hFc)
AI835281,poliovirus receptor-related 1 (herpesvirus entry me... |
Mouse | HEK293 Cells |
PVRL1/NECTIN1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.9 kDa and the accession number is Q9JKF6. | |||
TMPY-01571 |
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc)
HV1S,ED4,poliovirus receptor-related 1 (herpesvirus entry me... |
Human | HEK293 Cells |
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1. | |||
TMPY-02937 |
PVRL1/NECTIN1 Protein, Rat, Recombinant (His)
poliovirus receptor-related 1 (herpesvirus entry mediator C) |
Rat | HEK293 Cells |
PVRL1/NECTIN1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is A6J3U6. | |||
TMPJ-00629 |
TIGIT Protein, Cynomolgus, Recombinant (His)
VSTM3,V-set and transmembrane domain-containing protein 3,T-... |
Cynomolgus | HEK293 Cells |
T cell immunoreceptor with Ig and ITIM domains (TIGIT), also called VSIG9 and Vstm3, is a member of the CD28 family within the Ig superfamily of proteins. TIGIT contains an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM), and is expressed on regulatory, memory, activated T cells and NK cells. TIGIT binds to CD155(PVR) that appear on dendritic cells (DC), macrophages and endothelium with high affinity, and CD112(PVRL2) with lower... | |||
TMPK-00230 |
DNAM-1/CD226 Protein, Human, Recombinant (His & Avi), Biotinylated
CD226,PTA1,CD226 molecule,TLiSA1,DNAM1 |
Human | HEK293 Cells |
DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2. DNAM-1/CD226 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weig... | |||
TMPK-00229 |
DNAM-1/CD226 Protein, Human, Recombinant (His & Avi)
PTA1,TLiSA1,DNAM1,CD226,CD226 molecule |
Human | HEK293 Cells |
DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2. DNAM-1/CD226 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.9 kDa... |