首页工具

登录

搜索结果

Search Results for " phospholipase d "

21

抑制剂 & 化合物

2

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T76120	Phospholipase D
	PhospholipaseD (PLD) ，即磷脂酶 D，是磷脂酶超家族的一种酶，广泛存在于细菌、酵母、植物、动物和病毒中，常用于生化研究。PhospholipaseD 可以催化甘油磷脂的磷酸二酯键水解，产生磷脂酸和可溶性胆碱。PhospholipaseD 参与了多种疾病相关过程，包括糖尿病、动脉粥样硬化形成、肥胖、肿瘤发生、免疫反应和神经内分泌功能。
T11032	DHPG (RS)-3,5-DHPG,DL-Α-(3,5-二羟基苯基)甘氨酸	GluR	Neuroscience
	DHPG ((RS)-3,5-DHPG) 是一种氨基酸，是选择性代谢型谷氨酸受体 mGluR 的激动剂，也是与磷脂酶 D 耦合的 mGluR 的有效拮抗剂。
T4511	ST271 ST 271	Phospholipase; Tyrosine Kinases	Metabolism; Tyrosine Kinase/Adaptors
	ST271 是蛋白质酪氨酸激酶 (PTK) 抑制剂，抑制 fMet-Leu-Phe 和 PAF 引起的 phospholipase D 活化的IC50值分别为 6.7 和 9 μM。
T14321	ARN19874	Others	Others
	ARN19874 is a selective, reversible uncompetitive N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) activity inhibitor. With an IC50 of ~34 μM[1].
T3580L	FIPI HCl FIPI hydrochloride,FIPI
	FIPI is an effective and selective phospholipase D inhibitor that reduces mercury-induced lipid signaling and thus protects aortic endothelial cells from cytotoxicity.
T74687	N-Stearoylsphingomyelin
	N-Stearoylsphingomyelin (N-Stearoyl-D-sphingomyelin) 为抑制磷脂酶 Cδ1 (PLCδ1) 的鞘磷脂类化合物。
T41103	Compound 48/80 Poly-p-methoxyphenethylmethylamine
	Compound 48/80, also known as Poly-p-methoxyphenethylmethylamine, is a commonly utilized mast cell activator in animal and tissue models. This compound exerts its effect by stimulating trimeric G-proteins at the mast cell membrane, triggering degranulation through both phospholipase C and D pathways.
T35935	D-myo-Inositol-1,4,5-triphosphate trisodium Inositol 1,4,5-trisphosphate trisodium,Ins(1,4,5)-P3 trisodium,D-myo-Inositol-1,4,5-triphosphate (sodium salt),Ins(1,4,5)P3	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	D-myo-Inositol-1,4,5-triphosphate trisodium (Inositol 1,4,5-trisphosphate trisodium) 是由磷脂酶 C 介导的磷脂酰肌醇-4,5-二磷酸酯水解在细胞中产生的第二信使。D-myo-Inositol-1,4,5-triphosphate (sodium salt)与 Ins(1,4,5)P3受体结合，会导致钙通道的打开和细胞内钙的增加。
T35934	D-myo-Inositol-1,4,5-triphosphate (potassium salt)
	D-myo-Inositol-1,4,5-triphosphate (Ins(1,4,5)P3) is a second messenger produced in cells by phospholipase C (PLC) mediated hydrolysis of phosphatidyl inositol-4,5-biphosphate. It binds to one of several Ins(1,4,5)P3 receptors, each containing a calcium channel domain. Binding of Ins(1,4,5)P3 to the receptor results in opening of the calcium channels and an increase in intracellular calcium.
T75597	Loxosceles Spiniceps Venom
	Loxosceles Spiniceps Venom 是一种可以从Loxosceles Spiniceps 中获得的毒液。Loxosceles 蜘蛛的毒液是一种复杂的毒素混合物，富含蛋白质、糖蛋白和低分子质量多肽。目前已鉴定出几种蛋白类，包括类虾蛋白酶金属蛋白酶、低分子杀虫肽、抑制剂半胱氨酸结肽 (ICK) 和磷脂酶 D。其中独特的酶，鞘磷脂酶 D 负责坏死的发展。
T36907	1-Oleoyl Lysophosphatidic Acid Oleoyl-sn-3-Glycerophosphate,1-Oleoyl LPA,1-Oleoyl Lysophosphatidic Acid
	1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by phospholipase C (PLC) followed by phosphorylation of DAG by diglycerol kinase.[1] Hydrolysis of the fatty acid at the sn-2 position by phospholipase A2 (PLA2) yields bioactive LPA. LPA binds to one of five differe...
T37691	Phosphatidic Acids (egg) (ammonium salt)
	Phosphatidic acid is a phospholipid and an intermediate in glycerolipid biosynthesis. It is a transient intermediate in the synthesis of various phospholipid species that is synthesized de novo in cells via multiple routes, including the glycerol-3 phosphate and dihydroxyacetone phosphate pathways, enzymatic conversion of phosphatidylcholine by phospholipase D, and acetylation of lysophosphatidic acid by lysoPA-acyltransferase, among others. It has roles in shaping cellular membranes, cellular ...
T37123	1,2-Dioctanoyl PC
	Phosphatidylcholine (PC) species are a common class of phospholipids that comprise the mammalian cell membrane. 1,2-Dioctanoyl PC is a synthetic analog of natural phosphatidylcholine species containing saturated C8:O fatty acids in the sn-1 and sn-2 positions of the glycerol backbone. It exhibits a critical micelle concentration (CMC) value of 0.25 mM at 27°C. 1,2-Dioctanoyl PC serves as an efficient substrate for phospholipase D (PLD) as well as sPLA2 isozymes from bovine pancreas and bee venom...
T76463	Melittin free acid
	Melittin free acid为一种含有26个氨基酸的碱性多肽，主要来源于蜂毒，充当磷脂酶A2（PLA2）的激活剂。此化合物展现出0.4-60μM的广谱抗真菌活性，通过诱导细胞凋亡、抑制(1,3)-β-D-葡聚糖合成酶及参与其他生物通路来抑制真菌生长。
T75595	Loxosceles Bergeri Venom
	Loxosceles Bergeri Venom 是一种可以从Loxosceles Bergeri 中获得的毒液。Loxosceles 蜘蛛的毒液是一种复杂的毒素混合物，富含蛋白质、糖蛋白和低分子质量多肽。目前已鉴定出几种蛋白类，包括类虾蛋白酶金属蛋白酶、低分子杀虫肽、抑制剂半胱氨酸结肽 (ICK) 和磷脂酶 D。其中独特的酶，鞘磷脂酶 D 负责坏死的发展。
T75596	Loxosceles Pilosa Venom
	Loxosceles Pilosa Venom 是一种可以从Loxosceles Pilosa 中获得的毒液。Loxosceles 蜘蛛的毒液是一种复杂的毒素混合物，富含蛋白质、糖蛋白和低分子质量多肽。目前已鉴定出几种蛋白类，包括类虾蛋白酶金属蛋白酶、低分子杀虫肽、抑制剂半胱氨酸结肽 (ICK) 和磷脂酶 D。其中独特的酶，鞘磷脂酶 D 负责坏死的发展。
T36671	C2 Phytoceramide (t18:0/2:0)
	C2 Phytoceramide is a bioactive semisynthetic sphingolipid that inhibits formyl peptide-induced oxidant release (IC50 = 0.38 μM) in suspended polymorphonuclear cells. It increases COX-2 protein levels 15-fold through ERK signaling. It induces death of keratinocytes (20% viability) with an ED50 value of 30 μM, the same concentration at which 35% of cells in a TUNEL assay are apoptotic. C2 Phytoceramide also has antiproliferative effects in CHO cells, with greater than 80% cytotoxicity achieved at...
T35938	D-myo-Inositol-4-phosphate (ammonium salt)
	D-myo-Inositol-4-phosphate (Ins(4)P1) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-diphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intr...
T37060	D-myo-Inositol-1,3-diphosphate (sodium salt)
	D-myo-Inositol-1,3-phosphate (Ins(1,3)P) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3 is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in in...
T37057	D-myo-Inositol-1,2-diphosphate (sodium salt)
	Ins(1,2)P2 (sodium salt) is one of the many inositol phosphate (InsP) isomers that could act as small, soluble second messengers in the transmission of cellular signals. The most studied InsP Ins(1,4,5)P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(1,2)P2 (te...
T35936	D-myo-Inositol-1,4,6-triphosphate (sodium salt)
	D-myo-Inositol-1,4,6-phosphate (Ins(1,4,6)-P3) is a member of the inositol phosphate (InsP) family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)-P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)-P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in int...

化合物

Phospholipase D

Cat.No: T76120

Cat.No: T11032

Synonym: (RS)-3,5-DHPG,DL-Α-(3,5-二羟基苯基)甘氨酸

Target: GluR

Cat.No: T4511

Synonym: ST 271

Target: Phospholipase, Tyrosine Kinases

Cat.No: T14321

Target: Others

Cat.No: T3580L

Synonym: FIPI hydrochloride,FIPI

N-Stearoylsphingomyelin

Cat.No: T74687

Cat.No: T41103

Synonym: Poly-p-methoxyphenethylmethylamine

D-myo-Inositol-1,4,5-triphosphate trisodium

Cat.No: T35935

Synonym: Inositol 1,4,5-trisphosphate trisodium,Ins(1,4,5)-P3 trisodium,D-myo-Inositol-1,4,5-triphosphate (sodium salt),Ins(1,4,5)P3

Target: Calcium Channel

D-myo-Inositol-1,4,5-triphosphate (potassium salt)

Cat.No: T35934

Loxosceles Spiniceps Venom

Cat.No: T75597

1-Oleoyl Lysophosphatidic Acid

Cat.No: T36907

Synonym: Oleoyl-sn-3-Glycerophosphate,1-Oleoyl LPA,1-Oleoyl Lysophosphatidic Acid

Phosphatidic Acids (egg) (ammonium salt)

Cat.No: T37691

1,2-Dioctanoyl PC

Cat.No: T37123

Melittin free acid

Cat.No: T76463

Loxosceles Bergeri Venom

Cat.No: T75595

Loxosceles Pilosa Venom

Cat.No: T75596

C2 Phytoceramide (t18:0/2:0)

Cat.No: T36671

D-myo-Inositol-4-phosphate (ammonium salt)

Cat.No: T35938

D-myo-Inositol-1,3-diphosphate (sodium salt)

Cat.No: T37060

D-myo-Inositol-1,2-diphosphate (sodium salt)

Cat.No: T37057

D-myo-Inositol-1,4,6-triphosphate (sodium salt)

Cat.No: T35936

Cat. No.	Product Name	Target	Signaling Pathways
TN7075	Linocinnamarin 3-[4-(beta-D-Glucopyranosyloxy)phenyl]acrylic acid methyl ester	Phospholipase; Syk	Angiogenesis; Metabolism; Tyrosine Kinase/Adaptors
	Linocinnamarin (3-[4-(beta-D-Glucopyranosyloxy)phenyl]acrylic acid methyl ester) 是从 Fragaria ananassa Duch 中分离出来的。它对抗原刺激脱粒的抑制主要是由于 Syk/磷脂酶 Cgamma (PLCgamma) 途径的失活。
T83864	Plipastatin A1 SNA-60-367-3,Fengycin IX
	Plipastatin A1是一种在B. cereus中发现的脂肽类化合物，具有酶抑制活性和免疫抑制活性。它能抑制磷脂酶A2（PLA2）、PLC和PLD（IC50分别为2.9、1.3和1.4 µM）。Plipastatin A1（100 µg/ml）能抑制LPS诱导的B细胞爆发生成和Concanavalin A诱导的T细胞爆发生成。在体内，Plipastatin A1（0.1 mg/动物）能抑制小鼠的迟发型超敏反应。

天然产物

Cat.No: TN7075

Synonym: 3-[4-(beta-D-Glucopyranosyloxy)phenyl]acrylic acid methyl ester

Target: Phospholipase, Syk

Cat.No: T83864

Synonym: SNA-60-367-3,Fengycin IX

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼