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3

抑制剂 & 化合物

31

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T28877 SU9518

SU 9518,5-Br-SU6668,SU-9518,5 Br SU6668,5BrSU6668

SU9518, a tyrosine kinase inhibitor with PDGFRα specificity, can inhibit the development of proliferative vitreoretinopathy (PVR) in fibroblast and Müller cell rabbit models.
T78324 Ociperlimab

BGB-A1217

Ociperlimab 是一种人源化IgG1抗TIGIT抗体,能以高亲和力(KD= 0.135 nM)结合于TIGIT的细胞外结构域,并阻断其与配体PVRPVR-L2之间的相互作用,适用于癌症研究。
T82436 Etigilimab

OMP-313M32

Etigilimab (OMP-313M32) 为人源化IgG1单克隆抗体,旨在阻断TIGIT与PVR (CD155;脊髓灰质炎病毒受体)间的结合,进而抑制信号传导,通过诱导靶细胞凋亡实现其作用。

化合物

SU9518
Cat.No: T28877
Synonym: SU 9518,5-Br-SU6668,SU-9518,5 Br SU6668,5BrSU6668
Target:
Ociperlimab
Cat.No: T78324
Synonym: BGB-A1217
Target:
Etigilimab
Cat.No: T82436
Synonym: OMP-313M32
Target:
Cat. No. Product Name Species Expression System
TMPJ-00651 CD155/PVR Protein, Human, Recombinant (aa 21-343, His)

Poliovirus Receptor,PVS,Nectin-Like Protein 5,NECL-5,CD155,<...

Human HEK293 Cells
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension be...
TMPY-01612 CD155/PVR Protein, Rhesus, Recombinant (His)

poliovirus receptor

Rhesus HEK293 Cells
CD155/PVR Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.8 kDa and the accession number is Q0MSE6.
TMPK-00260 CD155/PVR Protein, Human, Recombinant (His & Avi)

NECL5,PVSFLJ25946,Necl-5,CD155,Tage4,PVR,HVED,FLJ25...

Human HEK293 Cells
CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR.
TMPY-05791 CD155/PVR Protein, Mouse, Recombinant (mFc)

Taa1,3830421F03Rik,poliovirus receptor,necl-5,D7Ertd458e,HVE...

Mouse HEK293 Cells
CD155/PVR Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 60.78 kDa and the accession number is Q8K094.
TMPY-00699 CD155/PVR Protein, Human, Recombinant (hFc)

poliovirus receptor,NECL5,HVED,PVS,Necl-5,TAGE4,CD155

Human HEK293 Cells
CD155/PVR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.8 kDa and the accession number is P15151-1.
TMPY-01386 CD155/PVR Protein, Human, Recombinant (His)

NECL5,TAGE4,PVS,CD155,HVED,Necl-5,poliovirus receptor

Human HEK293 Cells
CD155/PVR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P15151-1.
TMPY-00762 CD155/PVR Protein, Mouse, Recombinant (His)

poliovirus receptor,D7Ertd458e,mE4,Taa1,necl-5,PVS,3830421F0...

Mouse HEK293 Cells
CD155/PVR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28 kDa and the accession number is Q8K094.
TMPY-01150 Nectin-2 Protein, Mouse, Recombinant (His)

MPH,Pvs,Pvr,Cd112,AI325026,AI987993,poliovirus rece...

Mouse HEK293 Cells
Nectin-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36 kDa and the accession number is P32507-1.
TMPY-05596 CD155/PVR Protein, Human, Recombinant (His & Avi), Biotinylated

NECL5,Necl-5,TAGE4,HVED,CD155,PVS,poliovirus receptor

Human HEK293 Cells
CD155/PVR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 38.3 kDa and the accession number is P15151.2.
TMPY-01610 CD155/PVR Protein, Rat, Recombinant (His)

poliovirus receptor

Rat HEK293 Cells
CD155/PVR Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.8 kDa and the accession number is A6J8V8.
TMPY-06133 CD155/PVR Protein, Human, Recombinant (hFc & Avi), Biotinylated

TAGE4,CD155,NECL5,poliovirus receptor,HVED,Necl-5,PVS

Human HEK293 Cells
CD155/PVR Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 63.6 kDa and the accession number is P15151-1.
TMPY-05597 CD155/PVR Protein, Mouse, Recombinant (hFc & Avi), Biotinylated

PVS,Taa1,Tage4,CD155,poliovirus receptor,mE4,D7Ertd458e,HVED...

Mouse HEK293 Cells
CD155/PVR Protein, Mouse, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 62.9 kDa and the accession number is Q8K094.
TMPY-06094 PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His)

Cynomolgus,Rhesus HEK293 Cells
PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.3 kDa and the accession number is XP_005549281.1&XP_014989941.2.
TMPY-05579 PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated

PRR1,ED4,PVRR,nectin-1,OFC7,SK-12,CD111,CLPED1,HVEC...

Human HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1.
TMPK-00471 PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated

MGC2463,MGC104322,LPD,C7orf15,ALS2CR18,PREL2,ALS2CR9,RMO1,PR...

Mouse HEK293 Cells
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth. PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 42.7 kDa and the accession number is ...
TMPK-00470 PVRIG Protein, Mouse, Recombinant (hFc & Avi)

PREL-2,RMO1,MGC2463,C7orf15,MGC104322,PREL2,PVRIG,L...

Mouse HEK293 Cells
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth. PVRIG Protein, Mouse, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 42.70 kDa and the accession number is A0A1B0GS01.
TMPJ-00428 PVRIG Protein, Mouse, Recombinant (hFc)

MGC138297,transmembrane protein PVRIG,MGC104322,

Mouse HEK293 Cells
PVRIG Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 48-55 KDa and the accession number is A0A1B0GS01.
TMPJ-00436 PVRIG Protein, Cynomolgus, Recombinant (His)

CD112R,C7orf15MGC138295,MGC104322,transmembrane protein ...

Cynomolgus HEK293 Cells
PVRIG Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 20-30 KDa and the accession number is A0A2K5WVV8.
TMPY-05560 PVRL1/NECTIN1 Protein, Mouse, Recombinant (His)

PRR1,PRR,nectin-1,HIgR,Cd111,AI835281,HveC,poliovirus recept...

Mouse HEK293 Cells
PVRL1/NECTIN1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is Q9JKF6.
TMPY-01572 PVRL1/NECTIN1 Protein, Human, Recombinant (His)

HVEC,ED4,PRR1,PVRR1,nectin-1,HIgR,poliovirus recept...

Human HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.4 kDa and the accession number is Q15223-1.
TMPY-05165 PVRIG Protein, Human, Recombinant (hFc)

C7orf15,PREL-2,RalGDS/AF-6,RMO1,ALS2CR18,LPD,ALS2CR9,PREL2

Human HEK293 Cells
PVRIG Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.9 kDa and the accession number is Q6DKI7.
TMPY-06277 PVRIG Protein, Human, Recombinant (mFc)

C7orf15,RMO1,ALS2CR18,LPD,ALS2CR9,RalGDS/AF-6,PREL-2,PREL2

Human HEK293 Cells
PVRIG Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 40.15 kDa and the accession number is Q6DKI7-1.
TMPY-03030 PVRL1/NECTIN1 Protein, Rat, Recombinant (hFc)

poliovirus receptor-related 1 (herpesvirus entry mediator C)

Rat HEK293 Cells
PVRL1/NECTIN1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63.3 kDa and the accession number is A6J3U6.
TMPY-06301 PVRIG Protein, Human, Recombinant (hFc & Avi), Biotinylated

ALS2CR9,ALS2CR18,RalGDS/AF-6,PREL-2,LPD,C7orf15,PREL2,RMO1

Human HEK293 Cells
PVRIG Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 42.31 kDa and the accession number is Q6DKI7-1.
TMPJ-00435 PVRIG Protein, Cynomolgus, Recombinant (hFc)

C7orf15MGC138295,MGC138297,CD112R,MGC104322,transmembrane pr...

Cynomolgus HEK293 Cells
PVRIG Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-55 KDa and the accession number is A0A2K5WVV8.
TMPY-05196 PVRL1/NECTIN1 Protein, Mouse, Recombinant (hFc)

AI835281,poliovirus receptor-related 1 (herpesvirus entry me...

Mouse HEK293 Cells
PVRL1/NECTIN1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.9 kDa and the accession number is Q9JKF6.
TMPY-01571 PVRL1/NECTIN1 Protein, Human, Recombinant (hFc)

HV1S,ED4,poliovirus receptor-related 1 (herpesvirus entry me...

Human HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1.
TMPY-02937 PVRL1/NECTIN1 Protein, Rat, Recombinant (His)

poliovirus receptor-related 1 (herpesvirus entry mediator C)

Rat HEK293 Cells
PVRL1/NECTIN1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is A6J3U6.
TMPJ-00629 TIGIT Protein, Cynomolgus, Recombinant (His)

VSTM3,V-set and transmembrane domain-containing protein 3,T-...

Cynomolgus HEK293 Cells
T cell immunoreceptor with Ig and ITIM domains (TIGIT), also called VSIG9 and Vstm3, is a member of the CD28 family within the Ig superfamily of proteins. TIGIT contains an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM), and is expressed on regulatory, memory, activated T cells and NK cells. TIGIT binds to CD155(PVR) that appear on dendritic cells (DC), macrophages and endothelium with high affinity, and CD112(PVRL2) with lower...
TMPK-00230 DNAM-1/CD226 Protein, Human, Recombinant (His & Avi), Biotinylated

CD226,PTA1,CD226 molecule,TLiSA1,DNAM1

Human HEK293 Cells
DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2. DNAM-1/CD226 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weig...
TMPK-00229 DNAM-1/CD226 Protein, Human, Recombinant (His & Avi)

PTA1,TLiSA1,DNAM1,CD226,CD226 molecule

Human HEK293 Cells
DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2. DNAM-1/CD226 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.9 kDa...

重组蛋白

CD155/PVR Protein, Human, Recombinant (aa 21-343, His)
Cat.No: TMPJ-00651
Species: Human
Expression System: HEK293 Cells
CD155/PVR Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-01612
Species: Rhesus
Expression System: HEK293 Cells
CD155/PVR Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00260
Species: Human
Expression System: HEK293 Cells
CD155/PVR Protein, Mouse, Recombinant (mFc)
Cat.No: TMPY-05791
Species: Mouse
Expression System: HEK293 Cells
CD155/PVR Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00699
Species: Human
Expression System: HEK293 Cells
CD155/PVR Protein, Human, Recombinant (His)
Cat.No: TMPY-01386
Species: Human
Expression System: HEK293 Cells
CD155/PVR Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00762
Species: Mouse
Expression System: HEK293 Cells
Nectin-2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01150
Species: Mouse
Expression System: HEK293 Cells
CD155/PVR Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05596
Species: Human
Expression System: HEK293 Cells
CD155/PVR Protein, Rat, Recombinant (His)
Cat.No: TMPY-01610
Species: Rat
Expression System: HEK293 Cells
CD155/PVR Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06133
Species: Human
Expression System: HEK293 Cells
CD155/PVR Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05597
Species: Mouse
Expression System: HEK293 Cells
PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His)
Cat.No: TMPY-06094
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05579
Species: Human
Expression System: HEK293 Cells
PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPK-00471
Species: Mouse
Expression System: HEK293 Cells
PVRIG Protein, Mouse, Recombinant (hFc & Avi)
Cat.No: TMPK-00470
Species: Mouse
Expression System: HEK293 Cells
PVRIG Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00428
Species: Mouse
Expression System: HEK293 Cells
PVRIG Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00436
Species: Cynomolgus
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05560
Species: Mouse
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01572
Species: Human
Expression System: HEK293 Cells
PVRIG Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05165
Species: Human
Expression System: HEK293 Cells
PVRIG Protein, Human, Recombinant (mFc)
Cat.No: TMPY-06277
Species: Human
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03030
Species: Rat
Expression System: HEK293 Cells
PVRIG Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06301
Species: Human
Expression System: HEK293 Cells
PVRIG Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-00435
Species: Cynomolgus
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05196
Species: Mouse
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01571
Species: Human
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Rat, Recombinant (His)
Cat.No: TMPY-02937
Species: Rat
Expression System: HEK293 Cells
TIGIT Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00629
Species: Cynomolgus
Expression System: HEK293 Cells
DNAM-1/CD226 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00230
Species: Human
Expression System: HEK293 Cells
DNAM-1/CD226 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00229
Species: Human
Expression System: HEK293 Cells
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