首页工具

登录

搜索结果

Search Results for " prx "

Targets Recommended: 5-HT Receptor

29

抑制剂 & 化合物

9

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T8720	PRX-07034 hydrochloride PRX-07034	5-HT Receptor	GPCR/G Protein; Neuroscience
	PRX-07034 hydrochloride 是一种有效的高度选择性5-HT6受体拮抗剂，Ki 为 4-8 nM，IC50为 19 nM，可用于增强工作记忆和认知灵活性的研究。
T16669	PRX-08066	5-HT Receptor	GPCR/G Protein; Neuroscience
	PRX-08066是5-HT 受体2B 拮抗剂，IC50为3.4 nM，可诱导肺动脉的选择性血管舒张。
T68113	Naluzotan hydrochloride PRX 00023 hydrochloride	EGFR; 5-HT Receptor	Angiogenesis; GPCR/G Protein; JAK/STAT signaling; Neuroscience; Tyrosine Kinase/Adaptors
	Naluzotan hydrochloride (PRX 00023 hydrochloride) 是一种小分子、非氮杂吡酮、5-羟色胺(5-HT)1A 受体激动剂和sigma-1受体拮抗剂。在之前的临床试验中，该化合物在400多名患者中被证明安全且耐受性良好。
T16265	Naluzotan PRX 00023	EGFR; 5-HT Receptor	Angiogenesis; GPCR/G Protein; JAK/STAT signaling; Neuroscience; Tyrosine Kinase/Adaptors
	Naluzotan（PRX 00023）是一种新型高效的 5-HT1A 激动剂，IC50 和 Ki 值分别为约 20 nM 和 5.1 nM。Naluzotan 是一种有效的 hERG K+ 通道阻滞剂，IC50 值为 3800 nM。Naluzotan 具有抗焦虑活性，可用于研究抑郁症。
T77751	Imaprelimab PRX-003	Others	Others
	Imaprelimab (PRX-003) 是一种人源化抗黑素瘤细胞粘附分子 (MCAM) 的 IgG1κ 单克隆抗体。Imaprelimab 具有抗肿瘤活性，可用于研究炎症、肿瘤、银屑病。
T12565	PRX933 hydrochloride BVT-933 hydrochloride,GW876167 hydrochloride	5-HT Receptor	GPCR/G Protein; Neuroscience
	PRX933 hydrochloride (GW876167 hydrochloride) 是一种 5-HT2C 受体激动剂，可用于高血压急性期治疗的研究。
T6959	PRX-08066 Maleic acid	5-HT Receptor	GPCR/G Protein; Neuroscience
	PRX-08066 Maleic acid 是一种选择性 5-HT2B 受体拮抗剂，IC50 为 3.4 nM，可防止 MCT 大鼠模型中肺动脉高压的严重程度。
T21229	Pirenoxine Catalin,PRX
	Pirenoxine is an agent with anti-cataractogenesis activity by interacting with calcium ions or selenite which could lead to the formation of lens cataract.
T29115	VRX 03011 Potassium salt PRX-03140,PRX3140,NTC942,NTC-942,PRX-3140,PRX03140
	VRX 03011, a 5-HT4 partial agonist, is used potentially for the treatment of Alzheimer's disease.
T80966	Topsalysin PRX-302
	Topsalysin为PSA激活的前体蛋白质，同时是与人前列腺特异性抗原融合的孔隙形成蛋白（合成原气溶素）。研究显示Topsalysin能够抑制小鼠模型中的肿瘤生长。
T27518	GW-876167 PRX-00933,PNU-183933,GW876167,BVT933,BVT-933
	GW-876167, a 5-HT2C agonist, is used potentially for the treatment of obesity and glaucoma.
T80920	Tulinercept OPRX-106,TNFR-Fc,PRX-106
	Tulinercept (OPRX-106) 是单克隆抗体，适用于多种生化研究。
T63812	MrgprX2 antagonist-8	Others	Others
	MrgprX2 antagonist-8 是 MrgprX2 拮抗剂，能够用于研究炎症性疾病。
T12104	MRGPRX1 agonist 1	Others	Others
	MRGPRX1 agonist 1 是高效的 Mas 相关 G 蛋白偶联受体 X1 激动剂(EC50:50 nM)，对 MRGPRC11 无活性。MRGPRC11 具有缓解疼痛的作用。
T63766	MrgprX2 antagonist-7
	MrgprX2 antagonist-7 是一种抗过敏剂，具有明显的抗过敏效果，能够抑制肥大细胞脱颗粒。
T40176	MrgprX2 antagonist-5 MrgprX2 antagonist-5
	MrgprX2 antagonist-5, which acts as a potent antagonist of MrgprX2. It exhibits the ability to effectively inhibit the activity of MrgprX2, making it an ideal candidate for research related to inflammatory skin disorders.
T40268	MrgprX2 antagonist-4 MrgprX2 antagonist-4
	MrgprX2 antagonist-4 and compound B-51 E117, is a potent MrgprX2 antagonist. It specifically targets and inhibits the MrgprX2 receptor, making it suitable for investigating various inflammatory skin disorders.
T61332	MRGPRX4 modulator-1
	MRGPRX4 modulator-1 (compound 31-2) is a potent antagonist of the mas-related g-protein receptor X4 (MRGPR X4) with an IC50 < 100 nM against MRGPR4. It is utilized for the investigation of MRGPR X4 dependent diseases including itch, pain, and autoimmune disorders [1].
T80167	αC-Conotoxin PrXA αC-PrXA
	αC-Conotoxin PrXA为麻痹肽类神经毒素，亦是竞争性nAChR拮抗剂，对α1β1εδ（成人型）和α1β1γδ（胎儿型）nAChR的IC50值分别为1.8 nM和3.0 nM。该化合物通过与α-bungarotoxin竞争nAChR的α/δ及α/γ亚基界面，展现出对神经肌肉型nAChR的高度特异性。
T60466	MRGPRX1 agonist 2
	MRGPRX1 agonist 2 (compound 1a) 是有效的Mas 相关 G 蛋白偶联受体 X1 (MRGPRX1)的正变构调节剂（EC50 = 0.48 μM）。MRGPRX1 agonist 2 具有用于神经性疼痛的研究潜力。
T40271	MrgprX2 antagonist-3 MrgprX2 antagonist-3
	MrgprX2 antagonist-3 is a potent inhibitor of MrgprX2. It holds promising potential for investigating skin inflammatory disorders.
T40270	MrgprX2 antagonist-1 MrgprX2 antagonist-1
	MrgprX2 antagonist-1, is a novel MrgprX2 antagonist compound. It exhibits potential for exploration in studying cutaneous inflammatory disorders.
T60497	MRGPRX1 agonist 3
	MRGPRX1 agonist 3 (compound 1f) 是一种有效的正向变构调节剂，对Mas 相关 G 蛋白偶联受体 X1 (MRGPRX1)的EC50值为 0.22 μM，可用于研究神经性疼痛。
T40273	MrgprX2 antagonist-2 MrgprX2 antagonist-2
	MrgprX2 antagonist-2 is a potent antagonist of MrgprX2. It holds potential for investigating skin inflammatory disorders.
T63394	MrgprX2 antagonist-6
	MrgprX2 antagonist-6 是一种高效抗过敏剂，对肥大细胞脱颗粒具有抑制作用。
T63549	MRGPRX1 agonist 4
	MRGPRX1 agonist 4 是有效的、口服具有活力的 Mas 相关 G 蛋白偶联受体 X1 (MRGPRX1)正向变构调节剂 (EC50: 0.1 μM)。MRGPRX1 agonist 4 表现出良好的代谢稳定性以及口服生物利用度。MRGPRX1 agonist 4 能够改善人源性 MRGPRX1 神经疼痛模型小鼠行为性热过敏反应。
T61183	MRGPRX4 modulator-2
	MRGPRX4 modulator-2 (compound 1-55) is a highly potent modulator of MRGPR X4, displaying antagonist activity against this receptor with an IC50 value of less than 100 nM. Its application in the research of autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson's Syndrome, and various chronic itch conditions is notable [1].
T28906	T6603185 T-6603185,T 6603185
	T6603185 is a novel inhibitor of peroxiredoxin (Prx) and thioredoxin (Trx) systems.
T76889	Prasinezumab
	Prasinezumab (PRX 002) 为针对聚集α-突触核蛋白 (α-synuclein) 的人源化IgG1单克隆抗体，展现在帕金森病研究中的应用潜力。

化合物

PRX-07034 hydrochloride

Cat.No: T8720

Synonym: PRX-07034

Target: 5-HT Receptor

Cat.No: T16669

Target: 5-HT Receptor

Naluzotan hydrochloride

Cat.No: T68113

Synonym: PRX 00023 hydrochloride

Target: EGFR, 5-HT Receptor

Cat.No: T16265

Synonym: PRX 00023

Target: EGFR, 5-HT Receptor

Cat.No: T77751

Synonym: PRX-003

Target: Others

PRX933 hydrochloride

Cat.No: T12565

Synonym: BVT-933 hydrochloride,GW876167 hydrochloride

Target: 5-HT Receptor

PRX-08066 Maleic acid

Cat.No: T6959

Target: 5-HT Receptor

Cat.No: T21229

Synonym: Catalin,PRX

VRX 03011 Potassium salt

Cat.No: T29115

Synonym: PRX-03140,PRX3140,NTC942,NTC-942,PRX-3140,PRX03140

Cat.No: T80966

Synonym: PRX-302

Cat.No: T27518

Synonym: PRX-00933,PNU-183933,GW876167,BVT933,BVT-933

Cat.No: T80920

Synonym: OPRX-106,TNFR-Fc,PRX-106

MrgprX2 antagonist-8

Cat.No: T63812

Target: Others

MRGPRX1 agonist 1

Cat.No: T12104

Target: Others

MrgprX2 antagonist-7

Cat.No: T63766

MrgprX2 antagonist-5

Cat.No: T40176

Synonym: MrgprX2 antagonist-5

MrgprX2 antagonist-4

Cat.No: T40268

Synonym: MrgprX2 antagonist-4

MRGPRX4 modulator-1

Cat.No: T61332

αC-Conotoxin PrXA

Cat.No: T80167

Synonym: αC-PrXA

MRGPRX1 agonist 2

Cat.No: T60466

MrgprX2 antagonist-3

Cat.No: T40271

Synonym: MrgprX2 antagonist-3

MrgprX2 antagonist-1

Cat.No: T40270

Synonym: MrgprX2 antagonist-1

MRGPRX1 agonist 3

Cat.No: T60497

MrgprX2 antagonist-2

Cat.No: T40273

Synonym: MrgprX2 antagonist-2

MrgprX2 antagonist-6

Cat.No: T63394

MRGPRX1 agonist 4

Cat.No: T63549

MRGPRX4 modulator-2

Cat.No: T61183

Cat.No: T28906

Synonym: T-6603185,T 6603185

Cat.No: T76889

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00072	2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His) Thioredoxin-dependent peroxiredoxin BAS1,2-Cys peroxiredoxin...	Arabidopsis thaliana	P. pastoris (Yeast)
	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. May be an antioxidant enzyme particularly in the developing shoot and photosynthesizing leaf. 2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 24.4 kDa and the accession number is Q96291.
TMPY-02201	Peroxiredoxin 6 Protein, Human, Recombinant (His) p29,PRX,1-Cys,HEL-S-128m,peroxiredoxin 6,NSGPx,AOP2...	Human	E. coli
	PRDX6, a member of antioxidant protein superfamily, plays an important role in oxidative stress, catabolism of lipids and phospholipid lipisomes. Peroxiredoxin 6 (PRDX6) is involved in redox regulation of the cell and is thought to be protective against oxidant injury. Peroxiredoxin 6 (PRDX6) is a bifunctional protein with both glutathione peroxidase (GPx) and iPLA2 activities，which are concomitantly increased with the expression of PRDX6. PRDX6 promoted lung tumor growth in an in vivo allograft...
TMPY-02208	Peroxiredoxin 5 Protein, Human, Recombinant (His) B166,HEL-S-55,prx-V,ACR1,PMP20,AOEB166,SBBI10,P...	Human	E. coli
	Peroxiredoxin 5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18.5 kDa and the accession number is P30044-2.
TMPJ-00934	PRDX3 Protein, Human, Recombinant Protein MER5 homolog,Thioredoxin-Dependent Peroxide Reductas...	Human	E. coli
	Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Human PRDX3 protein has an antioxidant function and is localized in the mitochondrion. PRDX3 is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with M...
TMPJ-01098	PRDX4 Protein, Human, Recombinant (His) Prx-IV,Thioredoxin-Dependent Peroxide Reductase A03...	Human	E. coli
	Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. In addition, PRDX4 is probably involved in redox regulation of the cell, regulating the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-...
TMPJ-00933	PRDX5 Protein, Human, Recombinant (His) Antioxidant enzyme B166,Alu corepressor 1,Peroxiredoxin-5,PL...	Human	HEK293 Cells
	Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Peroxiredoxins is overexpressed in breast cancer tissues to a great extent suggesting that they has a proliferative effect and may be related to cancer development or progression. Peroxiredoxin 5 (PRDX5) is a thioredoxin peroxidase that belongs to the atypical 2-Cys class of the TSA/a...
TMPY-01276	Peroxiredoxin 1 Protein, Human, Recombinant (His) PAGA,peroxiredoxin 1,NKEFA,MSP23,PAG,TDPX2,PAGB,PRX...	Human	E. coli
	Peroxiredoxin 1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.9 kDa and the accession number is A0A384NPQ2.
TMPY-02200	Peroxiredoxin 2 Protein, Human, Recombinant (His) PRP,HEL-S-2a,TSA,NKEF-B,TDPX1,PTX1,TPX1,peroxiredoxin 2,...	Human	Baculovirus Insect Cells
	Peroxiredoxin 2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 24 kDa and the accession number is P32119.
TMPH-01640	MRGPRX2 Protein, Human, Recombinant (His)	Human	E. coli
	Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway c...

重组蛋白

2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His)

Cat.No: TMPH-00072

Species: Arabidopsis thaliana

Expression System: P. pastoris (Yeast)

Peroxiredoxin 6 Protein, Human, Recombinant (His)

Cat.No: TMPY-02201

Species: Human

Expression System: E. coli

Peroxiredoxin 5 Protein, Human, Recombinant (His)

Cat.No: TMPY-02208

Species: Human

Expression System: E. coli

PRDX3 Protein, Human, Recombinant

Cat.No: TMPJ-00934

Species: Human

Expression System: E. coli

PRDX4 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01098

Species: Human

Expression System: E. coli

PRDX5 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00933

Species: Human

Expression System: HEK293 Cells

Peroxiredoxin 1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01276

Species: Human

Expression System: E. coli

Peroxiredoxin 2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02200

Species: Human

Expression System: Baculovirus Insect Cells

MRGPRX2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01640

Species: Human

Expression System: E. coli

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼