首页工具

登录

搜索结果

Search Results for " pnp "

44

抑制剂 & 化合物

2

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T7767	FMoc-Val-Cit-PAB-PNP	Others	Others
	Fmoc-Val-Cit-PAB-PNP 是一种可降解的 ADC 连接剂，可用于合成抗体偶联药物。
T37575	GLcNAc1-b-PNP	Others	Others
	GLcNAc1-b-PNP 是N-乙酰基-β-氨基葡萄糖酶的发色底物，可用于量化人血清和尿液中N-乙酰基-β-D-氨基葡萄糖酶的活性。
T18318	MC-Val-Ala-PAB-PNP	Others	Others
	MC-Val-Ala-PAB-PNP 是一种用于合成抗体偶联药物的 linker，可降解。
T17692	Boc-Val-Cit-PAB-PNP	Others	Others
	Boc-Val-Cit-PAB-PNP 是一种可切割的 ADC 接头，用于合成抗体-药物偶联物。
T41083	pNP-ADPr pNP-ADPr,ADP-ribose-pNP
	pNP-ADPr is a colorimetric substrate employed in the first continuous activity assays for Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3). Its utilization facilitates research on poly(ADP-ribose) polymerase (PARP) enzymes.
T78401	pNP-ADPr disodium ADP-ribose-pNP disodium
	pNP-ADPr 二钠是一种用于检测Poly(ADP-ribose) glycohydrolase (PARG)和ADP-ribosyl hydrolase 3 (ARH3)活性的比色底物。它也适用于poly(ADP-ribose)polymerase (PARP)酶相关研究。
T3503	MC-Val-Cit-PABC-PNP Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate,马来酰亚胺基己酰-L-缬氨酸-L-瓜氨酸对氨基苄醇对硝基苯基碳酸脂	Others; AChR	Neuroscience; Others
	MC-Val-Cit-PABC-PNP 是一种组织蛋白酶可裂解的 ADC 肽接头，可用于合成抗体偶联药物。
T38739	Mal-PEG2-Val-Cit-PABA-PNP Mal-PEG2-Val-Cit-PABA-PNP
	Mal-PEG2-Val-Cit-PABA-PNP is a cleavable linker compound employed in the synthesis of antibody-drug conjugates (ADCs).
T19139	4-Nitrophenyl α-D-galactopyranoside PNP-alpha-D-Gal,4-硝基苯-α-D-吡喃半乳糖苷,PNP-α-D-Gal	Others	Others
	4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) 是 4-硝基苯基 (pNP) 糖吡喃糖苷的人工底物，可用于 α-半乳糖苷酶活性的检测。它用作底物能够显著增加 pNP 的释放量。
T39765	Mal-PEG1-Val-Cit-PAB-PNP Mal-PEG1-Val-Cit-PAB-PNP
	Mal-PEG1-Val-Cit-PAB-PNP is an ADC linker employed in the synthesis of ADCs, enabling cleavage.
T37733	AMP-PNP tetralithium
	Non-hydrolyzable AMP analog. Kir6 (KATP) channel blocker. Inhibits fast axonal transport and stabilizes the interaction of membranous organelles with microtubules. Brady (1985) A novel brain ATPase with properties expected for the fast axonal transport motor. Nature 317 73 PMID:2412134 \|Yount et al (1971) Adenylyl imidodiphosphate, an adenosine triphosphate analog containing a P-N-P linkage. Biochemistry 10 2484 PMID:4326768 \|Hehl and Neumcke (1994) KATP channels of mouse skeletal muscle: mechan...
T41022	β-D-glucuronide-pNP-carbonate
	β-D-glucuronide-pNP-carbonate is an ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs).
T38816	Fmoc-Val-Ala-PAB-PNP
	Fmoc-Val-Ala-PAB-PNP is a cleavable linker employed for the synthesis of antibody-drug conjugates (ADCs).
T18875	(Ac)Phe-Lys(Alloc)-PABC-PNP	Others	Others
	'(Ac)Phe-Lys(Alloc)-PABC-PNP serves as a valuable cleavable linker in the development of antibody-drug conjugates.'
T18512	OPSS-Val-Cit-PAB-PNP	Others	Others
	OPSS-Val-Cit-PAB-PNP is a cleavable linker employed in ADC (antibody-drug conjugates) synthesis [1].
T17690	Boc-Val-Ala-PAB-PNP	Others	Others
	Boc-Val-Ala-PAB-PNP is an ADC linker employed for the synthesis of antibody-drug conjugates (ADCs)[1]. This cleavable compound efficiently facilitates the attachment of drugs to antibodies, allowing for targeted delivery and release of therapeutic agents within the body, making it an important component in ADC development.
T17816	DBCO-Val-Cit-PABC-PNP	Others	Others
	DBCO-Val-Cit-PABC-PNP is a cleavable linker for antibody-drug conjugate (ADC) synthesis[1].
T17945	Fmoc-Ala-Ala-Asn-PABC-PNP	Others	Others
	Fmoc-Ala-Ala-Asn-PABC-PNP is a peptide cleavable ADC linker[1].
T15995	Mal-PEG4-Val-Cit-PAB-PNP	Others	Others
	Mal-PEG4-Val-Cit-PAB-PNP is a cleavable 4-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
T17688	Boc-Phe-(Alloc)Lys-PAB-PNP	Others	Others
	Boc-Phe-(Alloc)Lys-PAB-PNP serves as a cleavable linker in the synthesis of antibody-drug conjugates (ADCs).
T15953	Mal-amido-PEG2-Val-Cit-PAB-PNP	Others	Others
	Mal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable 2-unit polyethylene glycol (PEG) based ADC linker utilized in the construction of antibody-drug conjugates (ADCs)[1].
T14436	Azido-PEG3-Val-Cit-PAB-PNP	Others	Others
	Azido-PEG3-Val-Cit-PAB-PNP is a cleavable 3 unit PEG ADC linker employed for synthesizing antibody-drug conjugates (ADCs)[1]. It also serves as a PEG-based PROTAC linker for the synthesis of PROTACs[2].
T17726	Cbz-Phe-(Alloc)Lys-PAB-PNP	Others	Others
	Cbz-Phe-(Alloc)Lys-PAB-PNP serves as a cleavable linker in the design of antibody-drug conjugates (ADC).
T17981	Fmoc-Phe-Lys(Boc)-PAB-PNP	Others	Others
	Fmoc-Phe-Lys(Boc)-PAB-PNP is a cleavable antibody-drug conjugate (ADC) linker employed in the synthesis of ADCs.
T17980	Fmoc-Phe-Lys(Trt)-PAB-PNP	Others	Others
	Fmoc-Phe-Lys(Trt)-PAB-PNP is a cleavable linker for antibody-drug conjugate (ADC) synthesis, specifically designed for use in ADC synthesis.
T31835	Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP
	Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP is a peptide reagent for ADC conjugation that possesses a cleavable peptide sequence. The hydrophilic PEG spacer increases solubility in aqueous media.
T17387	Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP	Others	Others
	Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP is a cleavable linker utilized in the synthesis of antibody-drug conjugates (ADCs), which are innovative therapeutic agents that combine the targeting ability of antibodies with potent cytotoxic drugs.
T81870	Mal-VC-PAB-PNP-CDN-A
	Mal-VC-PAB-PNP-CDN-A是一种ADC活性分子与linker偶联物，具有特定的生物化学功能。
T77868	Mal-amide-PEG8-Val-Ala-PAB-PNP
	Mal-amide-PEG8-Val-Ala-PAB-PNP 是一款可降解的ADC linker，专门用于抗体偶联活性分子（ADC）的合成。
T77831	Fmoc-Glu-(Boc)-Val-Cit-PAB-PNP
	Fmoc-Glu-(Boc)-Val-Cit-PAB-PNP 是一种ADC linker，具有可降解 (cleavable) 特性，适用于抗体偶联活性分子 (ADC) 的合成。
T12399	Peldesine BCX 34	Nucleoside Antimetabolite/Analog; HIV Protease	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	Peldesine (BCX 34) 是一种有效的、竞争性的、可逆的和口服活性的嘌呤核苷磷酸化酶抑制剂。 Peldesine 抑制 T 细胞增殖，IC50 为 800 nM。 Peldesine 可用于皮肤 T 细胞淋巴瘤、牛皮癣和 HIV 感染的研究。
T67690	pNPG-1 4-Nitrophenyl β-D-glucuronide	Others	Others
	pNPG-1(4-Nitrophenyl β-D-glucuronide) 是一种葡萄糖醛酸单糖衍生物，是β-葡糖苷酶的显色底物。
T16554	PNPP	Others	Others
	PNPP 是用于 ELISA 和常规分光光度测定的碱性和酸性磷酸酶的非蛋白质显色底物。
T19522	PNPG 4-硝基苯-Β-D-吡喃葡萄糖苷,4-Nitrophenyl β-D-glucopyranoside	Others	Others
	PNPG (4-Nitrophenyl β-D-glucopyranoside) 是一种显色的β-D-葡糖苷酶底物，裂解后会产生黄色溶液。
T38127	pNPS-DHA
	pNPS-DHA is an arylamide derivative of docosahexaenoyl ethanolamide that has anti-allergic activity.1It inhibits degranulation of RBL-2H3 mast cells (IC50= 15 μM).pNPS-DHA (1,000 mg/kg) inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) in mice. 1.Kim, I.-H., Kanayama, Y., Nishiwaki, H., et al.Structure-activity relationships of fish oil derivatives with anti-allergic activity in vitro and in vivoJ. Med. Chem.62(21)9576-9592(2019)
TP1847	GLGPNPCRKKCYKRDFLGR
	GLGPNPCRKKCYKRDFLGR is a synthetic peptide.
T67822L	Ulodesine BCX4208	Endogenous Metabolite	Metabolism
	Ulodesine (BCX4208) 是一种嘌呤核苷磷酸化酶 (PNP) 抑制剂，对 PNP 有抑制作用，IC50 值为 2.293 nM/L。Ulodesine 可用于研究高尿酸血症。
T15337	Forodesine 呋咯地辛,BCX-1777,Immucillin-H	Others	Others
	Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine is an orally active inhibitor of purine nucleoside phosphorylase (IC50s: 0.48 to 1.57 nM for human, mouse, rat, monkey, and dog PNP). It could induce apoptosis in leukemic cells b
T9727	2'-Fluoro-2'-Deoxyadenosine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2′-Deoxy-2′-fluoroadenosine 可用于合成2 ' -脱氧-2 ' -氟修饰的寡核苷酸。它能被大肠杆菌嘌呤核苷磷酸化酶（PNP）有效地分解成毒性物 2-氟腺嘌呤，对表达大肠杆菌 PNP 的肿瘤表现出良好的体内活性。
T14964	CI 972 anhydrous CI 972 (anhydrous)	Others	Others
	CI 972 anhydrous is an inhibitor of purine nucleoside phosphorylase (PNP) (Ki: 0.83 μM) used as a T cell-selective immunosuppressive agent.
T11313	Forodesine hydrochloride BCX-1777 hydrochloride,Immucillin-H hydrochloride	Others	Others
	Forodesine hydrochloride (BCX-1777 hydrochloride), a potent inhibitor of human lymphocyte proliferation, effectively induces apoptosis in leukemic cells by elevating dGTP levels. This compound is an orally active, highly potent purine nucleoside phosphorylase (PNP) inhibitor, demonstrating IC50 values between 0.48 to 1.57 nM across human, mouse, rat, monkey, and dog PNP.
T78379	9-Deazaguanine	Others	Others
	9-Deazaguanine，一种核苷类似物，有效抑制嘌呤核苷磷酸化酶（PNP）。
T60799	Peldesine dihydrochloride
	Peldesine (BCX 34) dihydrochloride 是一种有效的，竞争性，可逆和口服活性的嘌呤核苷磷酸化酶 (PNP) 抑制剂，对人，大鼠和小鼠红细胞 (RBC)PNP 的 IC50分别为 36 nM，5 nM 和 32 nM。Peldesine dihydrochloride 还是一种 T 细胞 (T-cell) 增殖抑制剂，IC50为 800 nM。Peldesine dihydrochloride 可用于皮肤 T 细胞淋巴瘤，牛皮癣和 HIV 感染的研究。
T73745	Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside
	Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside (EPS; pNP-G7) 作为α-淀粉酶的底物，主要应用于测定α-淀粉酶的活性。

化合物

FMoc-Val-Cit-PAB-PNP

Cat.No: T7767

Target: Others

GLcNAc1-b-PNP

Cat.No: T37575

Target: Others

MC-Val-Ala-PAB-PNP

Cat.No: T18318

Target: Others

Boc-Val-Cit-PAB-PNP

Cat.No: T17692

Target: Others

Cat.No: T41083

Synonym: pNP-ADPr,ADP-ribose-pNP

pNP-ADPr disodium

Cat.No: T78401

Synonym: ADP-ribose-pNP disodium

MC-Val-Cit-PABC-PNP

Cat.No: T3503

Synonym: Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate,马来酰亚胺基己酰-L-缬氨酸-L-瓜氨酸对氨基苄醇对硝基苯基碳酸脂

Target: Others, AChR

Mal-PEG2-Val-Cit-PABA-PNP

Cat.No: T38739

Synonym: Mal-PEG2-Val-Cit-PABA-PNP

4-Nitrophenyl α-D-galactopyranoside

Cat.No: T19139

Synonym: PNP-alpha-D-Gal,4-硝基苯-α-D-吡喃半乳糖苷,PNP-α-D-Gal

Target: Others

Mal-PEG1-Val-Cit-PAB-PNP

Cat.No: T39765

Synonym: Mal-PEG1-Val-Cit-PAB-PNP

AMP-PNP tetralithium

Cat.No: T37733

β-D-glucuronide-pNP-carbonate

Cat.No: T41022

Fmoc-Val-Ala-PAB-PNP

Cat.No: T38816

(Ac)Phe-Lys(Alloc)-PABC-PNP

Cat.No: T18875

Target: Others

OPSS-Val-Cit-PAB-PNP

Cat.No: T18512

Target: Others

Boc-Val-Ala-PAB-PNP

Cat.No: T17690

Target: Others

DBCO-Val-Cit-PABC-PNP

Cat.No: T17816

Target: Others

Fmoc-Ala-Ala-Asn-PABC-PNP

Cat.No: T17945

Target: Others

Mal-PEG4-Val-Cit-PAB-PNP

Cat.No: T15995

Target: Others

Boc-Phe-(Alloc)Lys-PAB-PNP

Cat.No: T17688

Target: Others

Mal-amido-PEG2-Val-Cit-PAB-PNP

Cat.No: T15953

Target: Others

Azido-PEG3-Val-Cit-PAB-PNP

Cat.No: T14436

Target: Others

Cbz-Phe-(Alloc)Lys-PAB-PNP

Cat.No: T17726

Target: Others

Fmoc-Phe-Lys(Boc)-PAB-PNP

Cat.No: T17981

Target: Others

Fmoc-Phe-Lys(Trt)-PAB-PNP

Cat.No: T17980

Target: Others

Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP

Cat.No: T31835

Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP

Cat.No: T17387

Target: Others

Mal-VC-PAB-PNP-CDN-A

Cat.No: T81870

Mal-amide-PEG8-Val-Ala-PAB-PNP

Cat.No: T77868

Fmoc-Glu-(Boc)-Val-Cit-PAB-PNP

Cat.No: T77831

Cat.No: T12399

Synonym: BCX 34

Target: Nucleoside Antimetabolite/Analog, HIV Protease

Cat.No: T67690

Synonym: 4-Nitrophenyl β-D-glucuronide

Target: Others

Cat.No: T16554

Target: Others

Cat.No: T19522

Synonym: 4-硝基苯-Β-D-吡喃葡萄糖苷,4-Nitrophenyl β-D-glucopyranoside

Target: Others

Cat.No: T38127

GLGPNPCRKKCYKRDFLGR

Cat.No: TP1847

Cat.No: T67822L

Synonym: BCX4208

Target: Endogenous Metabolite

Cat.No: T15337

Synonym: 呋咯地辛,BCX-1777,Immucillin-H

Target: Others

2'-Fluoro-2'-Deoxyadenosine

Cat.No: T9727

Target: Nucleoside Antimetabolite/Analog

CI 972 anhydrous

Cat.No: T14964

Synonym: CI 972 (anhydrous)

Target: Others

Forodesine hydrochloride

Cat.No: T11313

Synonym: BCX-1777 hydrochloride,Immucillin-H hydrochloride

Target: Others

Cat.No: T78379

Target: Others

Peldesine dihydrochloride

Cat.No: T60799

Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside

Cat.No: T73745

Cat. No.	Product Name	Target	Signaling Pathways
T8083	Pyridoxal 5'-phosphate monohydrate Pyridoxal phosphate monohydrate,Pyridoxal 5-phosphate monohydrate,5-磷酸吡哆醛	Others	Others
	Pyridoxal 5'-phosphate monohydrate 是维生素 B6的活性形式，也是多种酶的重要辅因子。它是维生素 B6 在细胞内磷酸化过程中重要的辅酶变异体，能够与其他变异体（如 PNP 、 PMP）发生互换。
T1709	2'-Deoxyinosine Guanine deoxyriboside,Deoxyinosine,2'-脱氧肌苷	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxyinosine (Guanine deoxyriboside) 具有抑制人癌细胞株生长的活性，并发现其与嘌呤核苷磷酸化酶缺乏有关。

天然产物

Pyridoxal 5'-phosphate monohydrate

Cat.No: T8083

Synonym: Pyridoxal phosphate monohydrate,Pyridoxal 5-phosphate monohydrate,5-磷酸吡哆醛

Target: Others

2'-Deoxyinosine

Cat.No: T1709

Synonym: Guanine deoxyriboside,Deoxyinosine,2'-脱氧肌苷

Target: Others, Endogenous Metabolite

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼