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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T23127 |
PD-161570
PD 161570 |
EGFR; FGFR; PDGFR; Src | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
PD-161570 是一种有效的 ATP 竞争性人 FGF-1 受体抑制剂,IC50 为 39.9 nM,Ki 为 42 nM。它还是骨形态发生蛋白 (BMPs) 和TGF-β信号抑制剂。它抑制PDGF 刺激的自磷酸化和FGF-1受体磷酸化,IC50分别为 450 和 622 nM。它抑制 PDGFR、EGFR 和 c-Src 酪氨酸激酶,IC50 值分别为 310、240 和 44 nM。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00481 |
PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)
PDGF R beta,PDGFRB,PDGFR-2,PDGF-R... |
Cynomolgus | HEK293 Cells |
Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β signalling, may be crucial for restoration of BBB integrity after cerebral ischemia and therefore represents a novel potential therapeutic target. | |||
TMPK-00422 |
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated
PDGFR-2,PDGF R β/CD140b,PDGFR1,CD140B,... |
Human | HEK293 Cells |
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa and the accession number is P09619. | |||
TMPK-00421 |
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)
PDGFR1,CD140B,PDGFR-2,PDGF R β/CD140b,PDGF... |
Human | HEK293 Cells |
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa and the accession number is P09619. | |||
TMPK-01050 |
PDGF R beta/CD140b Protein, Canine, Recombinant (His)
JTK12,PDGF R β,PDGFR-β,PDGFR,PDGFR |
Canine | HEK293 Cells |
PDGF R beta/CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.25 kDa and the accession number is Q6QNF3. | |||
TMPY-05497 |
PDGFRB Protein, Human, Recombinant (hFc)
PDGFR,CD140B,PENTT,JTK12,KOGS,platelet-derived grow... |
Human | HEK293 Cells |
PDGFRB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.8 kDa and the accession number is P09619-1. | |||
TMPY-04937 |
PDGFRB Protein, Human, Recombinant (His), Biotinylated
platelet-derived growth factor receptor, beta polyp... |
Human | HEK293 Cells |
PDGFRB Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is P09619-1. | |||
TMPY-01207 |
PDGFRB Protein, Human, Recombinant (His)
CD140B,IMF1,KOGS,PDGFR,PDGFR-1,platelet-de... |
Human | HEK293 Cells |
PDGFRB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is P09619-1. | |||
TMPY-05358 |
PDGFRB Protein, Human, Recombinant
PENTT,platelet-derived growth factor receptor, beta... |
Human | HEK293 Cells |
PDGFRB Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 56.2 kDa and the accession number is P09619-1. |