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16

抑制剂 & 化合物

12

天然产物

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Cat. No. Product Name Target Signaling Pathways
T13036L Sulfosuccinimidyl oleate sodium

Sulfo-N-succinimidyl oleate sodium

Others Others
Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) 是一种长链脂肪酸。它可以抑制脂肪酸转运到细胞中。它具有抗炎作用。
T13036 Sulfosuccinimidyl oleate

Sulfo-N-succinimidyl oleate

Mitophagy Autophagy
Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) (Sulfo-N-succinimidyl oleate) 是一种长链脂肪酸,可抑制脂肪酸运输到细胞。Sulfosuccinimidyl oleate 是一种有效且不可逆的线粒体呼吸链抑制剂。Sulfosuccinimidyl oleate 与小胶质细胞表面上的CD36受体结合,具有抗炎效果。
T20650 Triethanolamine oleate

Tea-oleate,Trietol

Triethanolamine oleate is a nonionic surfactant
T33471 Monoethanolamine Oleate

FO-611,Ethamolin,brand name: Ethamolin,FO 611,FO611

Monoethanolamine Oleate (Etamolin, FO-611) is a hardening agent used in the treatment of varicose and esophageal veins.
T71479 Kahweol oleate

Kahweol oleate is emi-syntetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing cell cycle arrest and apoptosis in oral squamous cell carcinoma cells, preventing aflatoxin B1 induced DNA adduct formation, and suppressing H2O2-induced DNA damage and oxidative stress.
T28232 Oleoylestrone

Estrone 3-oleate,MP 101,MP-101,MP101

Antioxidant oxidation-reduction
Oleoylestrone (MP-101) 存在于血浆和脂肪组织中,具有潜在的抗氧化作用,可诱导大鼠体内脂肪的流失,可用于减肥。
T31286 Decaglyceryl monooleate

Hexaglyceryl oleate,Polyglyceryl-10 oleate,Polyglyceryl-3 oleate,Polyglyceryl-6 oleate,Triglyceryl monooleate

Decaglyceryl monooleate is a biochemical.
T78386 4-Methylumbelliferyl oleate

4-Methylumbelliferyl oleate是酸性及碱性脂肪酶的荧光底物,能被脂肪酶裂解,从而释放出4-Methylumbelliferyl(Ex/Em=320/450 nm)。
T71480 Kahweol linoleate

Kahweol linoleate is a semi-syntetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing cell cycle arrest and apoptosis in oral squamous cell carcinoma cells, preventing aflatoxin B1 induced DNA adduct formation, and suppressing H2O2-induced DNA damage and oxidative stress.
T36830 9-Nitrooleate

Nitrated unsaturated fatty acids, such as 10- and 12-nitrolinoleate , cholesteryl nitrolinoleate, and nitrohydroxylinoleate, represent a new class of endogenous lipid-derived signalling molecules. LNO2 isomers serve as potent endogenous ligands for PPARγ and can also decompose or be metabolized to release nitric oxide. 9-Nitrooleate is one of two regioisomers of nitrooleate, the other being 10-nitrooleate (OA-NO2; used for the mixture of isomers), which are formed by nitration of oleic acid in a...
T65442 Sorbitan monooleate

Sorbitan monooleate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65442,CAS号为 1338-43-8。
T31288 Decaglyceryl tetraoleate

Polyglyceryl-10 tetraoleate

Decaglyceryl tetraoleate is a biochemical.
T21085 Decaglyceryl dioleate

Polyglyceryl-10 dioleate

Decaglyceryl dioleate is a bioactive chemical.
T20381 Cetyl glycol

NSC-71525,NSC 71525,1,2-十六烷二醇,NSC71525

Others Others
Cetyl glycol (NSC-71525) 有利于金属有机前体的分解、中间体 Co(2+)Fe(3+)-油酸配合物的形成以及纳米颗粒在较低温度下的成核。 Cetyl glycol 是一种可用于化妆品的还原剂。
T35448 10-Thiastearic Acid

Heteroatom-substituted fatty acids have been observed to modulate the extension and desaturating of fatty acids, and to influence their distribution within phospholipids pools. 10-Thiastearic acid inhibits desaturation of radiolabeled stearate to oleate in rat hepatocytes and hepatoma cells by more than 80% at a concentration of 25 μM. This activity is associated with a hypolipidemic effect, making this 10-thiastearic acid a useful tool for evaluating new anti-obesity therapeutics.
T83767 4-Hydroxyphenylglyoxylic Acid

UK 22486

4-Hydroxyphenylglyoxylic acid 是一种抑制剂,针对 carnitine palmitoyltransferase 1 (CPT1),同时也是前药 oxfenicine 的活性代谢物。在 200 至 1,000 µM 的浓度范围内,该化合物能够抑制离体大鼠肝线粒体中的 CPT1,并能够抑制离体大鼠肝细胞中的油酸氧化。

化合物

Sulfosuccinimidyl oleate sodium
Cat.No: T13036L
Synonym: Sulfo-N-succinimidyl oleate sodium
Target: Others
Sulfosuccinimidyl oleate
Cat.No: T13036
Synonym: Sulfo-N-succinimidyl oleate
Target: Mitophagy
Triethanolamine oleate
Cat.No: T20650
Synonym: Tea-oleate,Trietol
Target:
Monoethanolamine Oleate
Cat.No: T33471
Synonym: FO-611,Ethamolin,brand name: Ethamolin,FO 611,FO611
Target:
Kahweol oleate
Cat.No: T71479
Synonym:
Target:
Oleoylestrone
Cat.No: T28232
Synonym: Estrone 3-oleate,MP 101,MP-101,MP101
Target: Antioxidant
Decaglyceryl monooleate
Cat.No: T31286
Synonym: Hexaglyceryl oleate,Polyglyceryl-10 oleate,Polyglyceryl-3 oleate,Polyglyceryl-6 oleate,Triglyceryl monooleate
Target:
4-Methylumbelliferyl oleate
Cat.No: T78386
Synonym:
Target:
Kahweol linoleate
Cat.No: T71480
Synonym:
Target:
9-Nitrooleate
Cat.No: T36830
Synonym:
Target:
Sorbitan monooleate
Cat.No: T65442
Synonym:
Target:
Decaglyceryl tetraoleate
Cat.No: T31288
Synonym: Polyglyceryl-10 tetraoleate
Target:
Decaglyceryl dioleate
Cat.No: T21085
Synonym: Polyglyceryl-10 dioleate
Target:
Cetyl glycol
Cat.No: T20381
Synonym: NSC-71525,NSC 71525,1,2-十六烷二醇,NSC71525
Target: Others
10-Thiastearic Acid
Cat.No: T35448
Synonym:
Target:
4-Hydroxyphenylglyoxylic Acid
Cat.No: T83767
Synonym: UK 22486
Target:
Cat. No. Product Name Target Signaling Pathways
T19237 Cholesteryl oleate

胆固醇油酸酯,Oleoylcholesterol,Cholesterol Oleate,Cholesteryl cis-9-octadecenoate

Endogenous Metabolite Metabolism
Cholesteryl oleate (Cholesteryl cis-9-octadecenoate) 是胆固醇的酯化形式,可用于合成固体脂质纳米颗粒。
T36390 Sodium oleate

Oleic acid sodium salt,Sodium oleate,cis-9-Octadecenoic acid sodium salt

ATPase Membrane transporter/Ion channel
Sodium oleate (cis-9-Octadecenoic acid sodium salt) (Oleic acid sodium) 是人脂肪细胞和其他组织中最常见的单不饱和脂肪酸钠盐。Sodium oleate 是一种 Na+/K+ ATP 酶激活剂。
T19316 Ethyl oleate

Others Others
Ethyl oleate 是由油酸和乙醇的缩合形成的脂肪酸酯。它是纳米结构脂质载体 (NLC) 中的液体脂质成分。其中 NLC 是一种口服有活性的反式阿魏酸的给药载体。
T2O2667 Methyl Oleate

油酸甲酯,oleic acid methyl ester,Methyl cis-9-Octadecenoate,cis-9-Octadecenoic Acid methyl ester

Others Others
Methyl Oleate (cis-9-Octadecenoic Acid methyl ester) 是脂肪酸甲酯。它能够显著提高抗氧化能力,但也明显削弱二烷基二硫代磷酸锌的抗磨能力。
T2O2668 Oleic acid

Elaidoic acid,9Z-Octadecenoic acid,Oleate,9-Octadecenoic Acid,Glycon Wo,9-cis-Octadecenoic acid,油酸

Apoptosis; ATPase; Others; Endogenous Metabolite Apoptosis; Membrane transporter/Ion channel; Metabolism; Others
Oleic acid (Glycon Wo) 属于天然产物,是一种常见的饱和脂肪酸,在存在于多种动物、植物的脂肪和油脂中。Palmitic acid 是一种 Na+/K+ATP 酶激活剂。
T2P2810 Methyl Linoleate

Linoleic acid methyl ester,亚油酸甲酯,Telfairic Acid methyl ester

Antioxidant oxidation-reduction
Methyl Linoleate (Telfairic Acid methyl ester) 是一种 Sageretia thea 果实的主要活性成分,能够下调小眼畸形相关转录因子和酪氨酸酶相关蛋白,是一种主要的抗黑色素生成化合物。
T8276 Methyl palmitoleate

Others Others
Methyl palmitoleate 是棕榈油酸的类似物,也是一种脂肪酸甲酯,具有细胞保护性和促进生长性。
TN6951 Ethyl linoleate

亚油酸乙酯

Others Others
Ethyl linoleate 对动脉粥样硬化病变的发展和炎症介质的表达有抑制作用。
T5214 Cholesteryl linoleate

CE(18:2(9Z,12Z)),Cholesterol Linoleate,Linoleic Acid cholesteryl ester,胆甾烯基亚油酸酯

Others; Endogenous Metabolite Metabolism; Others
Cholesteryl linoleate (Linoleic Acid cholesteryl ester) 是低密度脂蛋白和动脉粥样硬化病变中主要的胆固醇酯。它存在于 LDL 中的胆固醇酯,利用 LDL 受体相关蛋白转移到表达 15-脂氧合酶的巨噬细胞和 CHO 细胞的质膜,被氧化形成胆固醇亚油酸氢过氧化物。
T25457 Glyceryl monolinoleate

Emalsy MU,Linolein, mono-,Sunsoft 8090,Rikemal MU 100

Glyceryl monolinoleate can inactivate or inhibit African Swine Fever virus.
T81212 Sarmenoside II

Sarmenoside II为一种黄酮醇苷,能够抑制脂质积聚。该化合物在HepG2细胞中抑制油酸白蛋白诱导的脂质积累,其100 μM浓度下的抑制率约为30%。
T81326 Quercetin 3-O-Glc-(1→2)-Rha-7-O-Rha

Quercetin 3-O-Glc-(1→2)-Rha-7-O-Rha,一种黄酮醇苷,未对油酸白蛋白诱导的脂质积累显示显著抑制效应。

天然产物

Cholesteryl oleate
Cat.No: T19237
Synonym: 胆固醇油酸酯,Oleoylcholesterol,Cholesterol Oleate,Cholesteryl cis-9-octadecenoate
Target: Endogenous Metabolite
Sodium oleate
Cat.No: T36390
Synonym: Oleic acid sodium salt,Sodium oleate,cis-9-Octadecenoic acid sodium salt
Target: ATPase
Ethyl oleate
Cat.No: T19316
Synonym:
Target: Others
Methyl Oleate
Cat.No: T2O2667
Synonym: 油酸甲酯,oleic acid methyl ester,Methyl cis-9-Octadecenoate,cis-9-Octadecenoic Acid methyl ester
Target: Others
Oleic acid
Cat.No: T2O2668
Synonym: Elaidoic acid,9Z-Octadecenoic acid,Oleate,9-Octadecenoic Acid,Glycon Wo,9-cis-Octadecenoic acid,油酸
Target: Apoptosis, ATPase, Others, Endogenous Metabolite
Methyl Linoleate
Cat.No: T2P2810
Synonym: Linoleic acid methyl ester,亚油酸甲酯,Telfairic Acid methyl ester
Target: Antioxidant
Methyl palmitoleate
Cat.No: T8276
Synonym:
Target: Others
Ethyl linoleate
Cat.No: TN6951
Synonym: 亚油酸乙酯
Target: Others
Cholesteryl linoleate
Cat.No: T5214
Synonym: CE(18:2(9Z,12Z)),Cholesterol Linoleate,Linoleic Acid cholesteryl ester,胆甾烯基亚油酸酯
Target: Others, Endogenous Metabolite
Glyceryl monolinoleate
Cat.No: T25457
Synonym: Emalsy MU,Linolein, mono-,Sunsoft 8090,Rikemal MU 100
Target:
Sarmenoside II
Cat.No: T81212
Synonym:
Target:
Quercetin 3-O-Glc-(1→2)-Rha-7-O-Rha
Cat.No: T81326
Synonym:
Target:
TargetMol Loading
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