Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1567 |
Olanzapine
LY170053,奥氮平 |
Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; AChR | GPCR/G Protein; Neuroscience |
Olanzapine (LY170053) 是一种非典型抗精神病药,目前用于治疗精神分裂症和双相情感障碍。 | |||
T28231 |
Olanzapine N-Oxide
|
Others | Others |
Olanzapine N-Oxide 是 Olanzapine 的代谢产物,Olanzapine 具有抗精神病活性。 | |||
T35716 |
N-desmethyl Olanzapine
4'-Desmethylolanzapine |
P450; Drug Metabolite | Metabolism |
N-desmethyl Olanzapine 是一种非典型抗精神病化合物Olanzapinec 的代谢产物,是通过细胞色素 450(CYP)同工酶 CYP1A2 对奥氮平进行氧化代谢而形成的。 | |||
T68706 |
Olanzapine HCl
|
||
Olanzapine HCl is an atypical antipsychotic. It is approved by the U.S. Food and Drug Administration (FDA) for the treatment of schizophrenia and bipolar disorder. Olanzapine is structurally similar to clozapine and quetiapine. It is a dopamine antagonist and is classified as a thienobenzodiazepine. | |||
T37704 |
Olanzapine Lactam Impurity
|
||
Olanzapine lactam impurity is a potential impurity found in commercial preparations of olanzapine.1It is a degradation product formed by exposure to thermal or oxidative stress. 1.Baertschi, S.W., Brunner, H., Bunnell, C.A., et al.Isolation, identification, and synthesis of two oxidative degradation products of olanzapine (LY170053) in solid oral formulationsJ. Pharm. Sci.97(2)883-892(2008) | |||
T12291 |
Olanzapine D3
LY170053 D3 |
Others | Others |
Olanzapine D3 is the deuterium labeled Olanzapine. | |||
T70964 |
Olanzapine/Samidorphan
|
||
Olanzapine/Samidorphan is a combination of olanzapine and the opioid receptor antagonist samidorphan is under development for the treatment of schizophrenia and bipolar I disorder. The single-tablet combination treatment is intended to provide the efficacy of olanzapine while mitigating olanzapine-associated weight gain. | |||
T67386 | Olanzapine Thiolactam Impurity | ||
(Z)-1-(4-(4-Methylpiperazin-1-yl)-2-thioxo-1H-benzo[b][1,4]diazepin-3(2H)-ylidene)propan-2-one 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67386。 | |||
T19638 |
LY-301664
LY301664,奥氮平相关物质B,LY 301664 |
Others | Others |
LY-301664 是一种具有生物活性的奥氮平(Olanzapine)杂质。 | |||
T1376 |
2-Amino-5-methyl-3-thiophenecarbonitrile
|
COX | Immunology/Inflammation; Neuroscience |
2-Amino-5-methyl-3-thiophenecarbonitrile 常用于合成 Olanzapine。 |