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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T6290 Tanespimycin

坦螺旋霉素,17-AAG,CP 127374,NSC 330507,KOS 953

Apoptosis; Mitophagy; HSP; Antibacterial; Antibiotic; Autophagy Apoptosis; Autophagy; Cytoskeletal Signaling; Metabolism; Microbiology/Virology
Tanespimycin (KOS 953) 是一种 Hsp90 抑制剂,可选择性抑制 BT474 肿瘤细胞 Hsp90,IC50为 5 nM。它消耗细胞内 STK38/NDR1,并降低 STK38 激酶活性,还能下调stk38基因表达。

天然产物

Tanespimycin
Cat.No: T6290
Synonym: 坦螺旋霉素,17-AAG,CP 127374,NSC 330507,KOS 953
Target: Apoptosis, Mitophagy, HSP, Antibacterial, Antibiotic, Autophagy
Cat. No. Product Name Species Expression System
TMPY-03443 NDRG1 Protein, Human, Recombinant (His)

TARG1,PROXY1,RIT42,NDR1,...

Human E. coli
NDRG1 gene is a member of the N-Myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Mutations in the NDRG1 gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. NDRG1 is a stress-responsive pro...

重组蛋白

NDRG1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03443
Species: Human
Expression System: E. coli
TargetMol Loading
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